Nicholls State Colonels Odds
| Date | Opp | Close | Result | ATS/OU |
| Aug 23, 2025 | Incarnate Word | -
/ | | Live |
| Aug 30, 2025 | @Troy | -
/ | | Live |
| Sep 6, 2025 | West Georgia | -
/ | | Live |
| Sep 20, 2025 | @Texas State | -
/ | | 8:00 PM ET |
| Sep 27, 2025 | @Eastern Kentucky | -
/ | | 6:00 PM ET |
| Oct 4, 2025 | @Lamar | -
/ | | 4:00 PM ET |
| Oct 18, 2025 | @Stephen F. Austin | -
/ | | 7:00 PM ET |
| Oct 25, 2025 | McNeese | -
/ | | 4:00 PM ET |
| Nov 1, 2025 | Houston Christian | -
/ | | 4:00 PM ET |
| Nov 15, 2025 | Northwestern State | -
/ | | 6:00 PM ET |
| Nov 20, 2025 | @Southeastern Louisiana | -
/ | | 9:00 PM ET |
• 
308903 Incarnate Word 0 - 0 
308904 Nicholls State 0 - 0