Philadelphia Phillies vs. Houston Astros Game 6 Picks, Predictions, Odds

The Philadelphia Phillies and Houston Astros will meet for Game 6 of the World Series on Saturday night. First pitch is scheduled for 8:03 PM ET at Minute Maid Park in Houston, Texas and can be viewed on FOX.


The Phillies have dug themselves into a hole after losing at home in Game 5. They will now have to do the unthinkable and beat the Astros in back-to-back games on the road, but hey if any team is capable, it’s this Phillies team. The offense finished Game 5 with six hits, one home run, two total runs, and went 1-7 with runners in scoring position. They had their fair share of opportunities but failed to capitalize. Starting pitcher Noah Syndergaard gave up three hits and two runs in 3.0 innings of work. The other five pitchers gave up a combined six hits and one run in 6.0 innings of work. Right-handed pitcher Zack Wheeler (Postseason: 1-2, 2.67 ERA) is expected to start Game 6.  

After winning back-to-back road games the Astros now have two chances at home to become World Series champions. Houston has bounced back nicely after going scoreless in Game 3, putting up eight runs and holding the Phillies to just two runs since then. The offense finished Game 5 with nine hits, one home run, three total runs, and went 1-11 with runners in scoring position. The bullpen was solid for the most part. Starting pitcher Justin Verlander gave up four hits and one run in 5.0 innings of work. He put himself in sticky situations multiple times but managed to pitch out of them. The other four pitchers held the Phillies to two hits and one run in 4.0 innings. Southpaw pitcher Framber Valdez (Postseason: 2-0, 1.42 ERA) is scheduled to start Saturday.  

While I think there is value in backing the Phillies here, I like the Astros to close this thing out in Game 6. Valdez has been fantastic in these playoffs, allowing just three runs across 19.0 innings of work. Wheeler has been great as well but looked a bit gassed in Game 2. This will be Wheeler’s sixth start of the postseason while Valdez will be taking the mound for the fourth time. The Phillies have had a phenomenal run but unfortunately, I think their season comes to an end on Saturday. Backing the Astros Moneyline here. 

Score Prediction: Astros 4, Phillies 2
Best Bet: Astros ML (-145)


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  • Date: Saturday, November 5, 2022
  • Matchup: NL East vs. AL West
  • Venue: Minute Maid Park
  • Location: Houston, Texas
  • Time-TV: 8:03 p.m. ET – FOX
  • Expert Picks


The Phillies are 11-5 SU and 12-4 ATS this postseason. The total has gone under in seven of their last 10 games when playing an opponent from the AL West. Going against this trend, the total has gone over in five of their last seven games played on a Saturday. Philadelphia is 4-10 in their past 14 games against American League opponents and 2-5 in their past seven when playing on the road against Houston.  

Philadelphia’s offense has come to a halt over the past two games. After averaging seven runs per game at home throughout the postseason, they managed to score a combined two runs in their past two games. Give credit to the Astros bullpen but you have to wonder if fatigue isn’t starting to become a factor. At this point Philadelphia has played four more games than the Astros. Houston has also started to walk Harper more often which seems to be making a difference. During these playoffs, the Phillies have had a batting average of .217, on base percentage of .296, slugging percentage of .410 and have scored 74 runs.  

The Phillies bullpen did a respectable job in Game 5. The only difference maker ended up being a solo shot by Jeremy Pena in the top of the fourth. Wheeler will look to force this series to a Game 7 as he takes the mound Saturday. Wheeler has made five starts this postseason and has been dominant. However, he did struggle in his most recent outing against Houston in Game 2, allowing six hits and five runs in 5.0 innings. Philadelphia needs a strong start from Wheeler or they stand no chance in this one. 



Houston is 10-2 SU and 7-5 ATS in these playoffs. The total has gone under in eight of their last 11 games. Following this trend, the total has gone under in four of their last six games against Philadelphia. The Astros are 7-1 in their last eight games at home and 5-2 in their last seven games when playing at home against the Phillies.  

The Astros offense has been consistent throughout these entire playoffs. As a team they have a postseason batting average of .232, on base percentage of .301, slugging percentage of .392 and have scored 49 runs. This team is particularly good at stringing together hits and creating little bits of momentum here and there. Jeremy Pena has been a monster in these playoffs with a batting average of .333 (18-54), four home runs, and eight RBIs. Alex Bregman has been key as well with a batting average of .292 (14-48), three home runs, and 11 RBIs.  

Verlander managed to redeem himself in Game 5 after a poor performance in Game 1. The relievers and closers were solid as well, which comes as no surprise if you’ve paid attention to this postseason. Expect a lot of ground balls in Game 6 with Valdez taking the mound. He has been great in these playoffs with an ERA of 1.42 through three starts. In his most recent start against the Phillies in Game 2, Valdez gave up four hits and one run in 6.1 innings of work. Expect a similar outing in Game 6. 


  • PHI: Bryce Harper - DH (Last Game: 1-2, 2 BB)
  • PHI: Kyle Schwarber - OF (Last Game: 1-4, HR, BB)
  • HOU: Jose Altuve - IF (Last Game: 2-4, BB, 2 R)
  • HOU: Jeremy Pena - IF (Last Game: 3-4, HR, 2 RBI)


  • PHI: Zack Wheeler - RHP
  • HOU: Framber Valdez - LHP