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Featured Last Updated Oct 1 2026, 1:15 PM

Colts vs. Commanders Predictions: High-Scoring Affair in London

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
14 minute read
Colts vs. Commanders Predictions: High-Scoring Affair in London

The Indianapolis Colts will take on the Washington Commanders in this week's NFL action. Kickoff is set for 9:30 AM EST at Tottenham Hotspur Stadium in London, England. The game will be broadcast live on NFL Network. Here's everything you need to know about Colts vs. Commanders odds, the latest college football spreads, college football over/unders and more.

IND @ WAS Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Indianapolis Colts 251 Colts
+1.5 -122 -2.5 -120 + -2.5 -120 + -2.5 -122 + -2.5 -118 + -2.5 -125 + -2.5 -125 + -2.5 -120 + -2.5 -121 + -3.5 -112  
Washington Commanders 252 Commanders
-1.5 +102 +2.5 even + +2.5 even + +2.5 +102 + +2.5 -103 + +2.5 +105 + +2.5 -105 + +2.5 even + +2.5 -104 + +3.5 -108  
Indianapolis Colts 251 Colts
o48.5 -110 o23.5 -115 + o23.5 -120 + o23.5 -115 + o23.5 -115 + o24.5 +105 + o23.5 -125 + o24.5 +110 + o23.5 -118 + o48.5 -108  
Washington Commanders 252 Commanders
u48.5 -110 u23.5 -105 + u23.5 even + u23.5 -105 + u23.5 -105 + u24.5 -125 + u23.5 -105 + u24.5 -150 + u23.5 -106 + u48.5 -112  
Indianapolis Colts 251 Colts
-110 -170 + -175 + -175 + -164 + -182 + N/A -170 + -186 + -192  
Washington Commanders 252 Commanders
-110 +145 + +140 + +145 + +137 + +148 + N/A +140 + +148 + +160  
Indianapolis Colts 251 Colts
+1.5 -122 -0.5 +110 + -0.5 even + -0.5 +102 + N/A -1.5 +110 + -0.5 even + -0.5 +105 + -1.5 +108 + -3.5 -112  
Washington Commanders 252 Commanders
-1.5 +102 +0.5 -130 + +0.5 -130 + +0.5 -122 + N/A +1.5 -136 + +0.5 -130 + +0.5 -125 + +1.5 -134 + +3.5 -108  
Indianapolis Colts 251 Colts
o48.5 -110 o9.5 -115 + o9.5 -120 + o9.5 -118 + N/A o9.5 -118 + o9.5 -120 + o9.5 -120 + o9.5 -118 + o48.5 -108  
Washington Commanders 252 Commanders
u48.5 -110 u9.5 -105 + u9.5 -105 + u9.5 -102 + N/A u9.5 -104 + u9.5 -110 + u9.5 -110 + u9.5 -106 + u48.5 -112  
Indianapolis Colts 251 Colts
-110 -155 + -165 + -175 + N/A -168 + N/A -170 + -165 + -192  
Washington Commanders 252 Commanders
-110 +130 + +130 + +145 + N/A +136 + N/A +130 + +133 + +160  
Indianapolis Colts 251 Colts
+1.5 -122 -1.5 -105 + N/A -2.5 -110 + N/A -1.5 -105 + -1.5 -115 + N/A -1.5 -106 + -3.5 -112  
Washington Commanders 252 Commanders
-1.5 +102 +1.5 -115 + N/A +2.5 -120 + N/A +1.5 -115 + +1.5 -115 + N/A +1.5 -117 + +3.5 -108  
Indianapolis Colts 251 Colts
o48.5 -110 o23.5 -120 + N/A o23.5 -118 + N/A o23.5 -110 + o23.5 -110 + N/A o23.5 -121 + o48.5 -108  
Washington Commanders 252 Commanders
u48.5 -110 u23.5 even + N/A u23.5 -102 + N/A u23.5 -110 + u23.5 -120 + N/A u23.5 -103 + u48.5 -112  
Indianapolis Colts 251 Colts
-110 -150 + N/A -160 + N/A -144 + N/A N/A -152 + -192  
Washington Commanders 252 Commanders
-110 +125 + N/A +124 + N/A +122 + N/A N/A +123 + +160  
Indianapolis Colts 251 Colts
+1.5 -122 N/A N/A -1.5 -110 + N/A -1.5 -106 + -1.5 -110 + N/A N/A -3.5 -112  
Washington Commanders 252 Commanders
-1.5 +102 N/A N/A +1.5 -120 + N/A +1.5 -116 + +1.5 -120 + N/A N/A +3.5 -108  
Indianapolis Colts 251 Colts
o48.5 -110 o13.5 -130 + N/A o13.5 -125 + N/A o14.5 -102 + o14.5 -105 + N/A N/A o48.5 -108  
Washington Commanders 252 Commanders
u48.5 -110 u13.5 even + N/A u13.5 -105 + N/A u14.5 -120 + u14.5 -125 + N/A N/A u48.5 -112  
Indianapolis Colts 251 Colts
-110 -160 + N/A -160 + N/A -160 + N/A N/A N/A -192  
Washington Commanders 252 Commanders
-110 +125 + N/A +124 + N/A +130 + N/A N/A N/A +160  
Indianapolis Colts 251 Colts
+1.5 -122 N/A N/A -0.5 +105 + N/A -1.5 +132 + -0.5 +110 + N/A N/A -3.5 -112  
Washington Commanders 252 Commanders
-1.5 +102 N/A N/A +0.5 -135 + N/A +1.5 -162 + +0.5 -145 + N/A N/A +3.5 -108  
Indianapolis Colts 251 Colts
o48.5 -110 o9.5 -120 + N/A o9.5 -140 + N/A o9.5 -114 + o9.5 -125 + N/A N/A o48.5 -108  
Washington Commanders 252 Commanders
u48.5 -110 u9.5 -110 + N/A u9.5 +110 + N/A u9.5 -108 + u9.5 -105 + N/A N/A u48.5 -112  
Indianapolis Colts 251 Colts
-110 -135 + N/A -140 + N/A -132 + N/A N/A N/A -192  
Washington Commanders 252 Commanders
-110 +105 + N/A +110 + N/A +108 + N/A N/A N/A +160  
Indianapolis Colts 251 Colts
+1.5 -122 -0.5 -110 + N/A -0.5 -115 + N/A -1.5 +112 + -0.5 -110 + N/A N/A -3.5 -112  
Washington Commanders 252 Commanders
-1.5 +102 +0.5 -120 + N/A +0.5 -115 + N/A +1.5 -136 + +0.5 -120 + N/A N/A +3.5 -108  
Indianapolis Colts 251 Colts
o48.5 -110 o13.5 -105 + N/A o13.5 -125 + N/A o13.5 -110 + o13.5 -110 + N/A N/A o48.5 -108  
Washington Commanders 252 Commanders
u48.5 -110 u13.5 -125 + N/A u13.5 -105 + N/A u13.5 -110 + u13.5 -120 + N/A N/A u48.5 -112  
Indianapolis Colts 251 Colts
-110 -140 + N/A -145 + N/A -142 + N/A N/A N/A -192  
Washington Commanders 252 Commanders
-110 +110 + N/A +114 + N/A +116 + N/A N/A N/A +160  

The Indianapolis Colts opened as a -3.5 point favorite to Washington. The total is set at over/under 48.5 total points scored by both teams combined.

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Updated on 10/1/26

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Colts vs. Commanders Prediction

These defenses are two of the worst in the league. PFF ranks the Colts as the 31st defense and the Commanders as the 24th. In addition to this, these two teams play relatively quick on offense. The Commanders average nearly 72 offensive snaps per game and have nearly a 7% big time throw rate.

This will be a game with a lot of plays and a high chance of big-chunk offensive plays. This should be a high scoring game.

Updated on 10/1/26

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Colts vs. Commanders Prediction: Colts vs. Commanders Over 48

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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