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Featured Last Updated Nov 15 2026, 5:06 PM

2026 College Football Odds Week 12: Lines, Spreads, Betting Trends on Biggest Games

Patrick Everson
Patrick Everson Sports Betting Expert
11 minute read
2026 College Football Odds Week 12: Lines, Spreads, Betting Trends on Biggest Games

College Football Week 12 Odds are short on marquee matchups. But there are still games that could impact College Football Playoff rankings.

LSU vs. Tennessee may well be the most notable game in Week 12 college football odds. Other key contests: UCLA vs. Michigan, Georgia vs. South Carolina and surprising Wake Forest vs. Georgia Tech.

Here’s everything you need to know about 2026 college football odds Week 12: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on college football Week 12odds and action.

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Updated on 11/15/26

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2026 College Football Odds for Week 12

Wake Forest vs. Georgia Tech Odds

  • Opening point spread: Wake Forest -21.5
  • Opening moneyline: Wake Forest TBA/Georgia Tech TBA
  • Opening total: Over/Under 57 points scored
  • Time: Noon ET Saturday (ESPN)

OPENING ODDS UPDATE: Wake Forest (9-1 SU/8-2 ATS is among the bigger surprises of the season and posted a statement win in Week 11. The Demon Deacons closed as 2.5-point road underdogs vs. SMU, then stormed to a 42-0 halftime lead en route to a 49-7 blowout.

Wake is on runs of 7-0 SU and 8-0 ATS. The Demon Deacons are very much in the ACC title/CFP conversation, currently ranked 13th. That's sure to change Tuesday night, when the latest rankings come out.

On the flip side, Georgia Tech (3-7 SU/2-8 ATS) is having a dismal season. However, the Yellow Jackets went to Clemson as 15.5-point road underdogs and departed with a 20-6 upset victory. That halted an 0-4 SU and ATS skid.

Circa Sports is well-regarded for its college football opening numbers, which often draw early sharp action. Circa opened Wake Forest -21.5 and nudged to -21 within a minute Sunday afternoon in college football Week 12 odds.

UCLA vs. Michigan Odds

UCLA @ Michigan Betting Odds

  • Spread
  • Total
  • Moneyline
  • Opening point spread: UCLA -6.5
  • Opening moneyline: UCLA TBA/Michigan TBA
  • Opening total: Over/Under 39 points scored
  • Time: 3:30 p.m. ET Saturday (CBS)

OPENING ODDS UPDATE: UCLA (10-0 SU/9-1 ATS) remained unblemished on the field in Week 11, while taking its first point-spread setback of the season. The Bruins got a stern challenge from Illinois, but held on for a 22-14 win laying 10.5 points at home.

UCLA QB Ty Dieffennbach suffered an elbow injury late in the first half and missed most of the third quarter. Dieffenbach then led a 75-yard touchdown drive to give the Bruins a little breathing room with a 19-7 lead.

UCLA is tied for the best spread-covering record in the country.

Michigan (5-5 SU/3-7 ATS) is having a very un-Michigan-like season, which continued in Week 11. The Wolverines were 10-point road pups vs. Oregon and got thumped 31-7.

Michigan has lost three of its last four SU and is 1-6 ATS in its last seven games.

Circa Sports opened UCLA-Michigan at Bruins -6.5 in Week 12 college football odds. It took 35 minutes Sunday afternoon, but the first move was straight to UCLA -5

LSU vs. Tennessee Odds

  • Opening point spread: Pick
  • Opening moneyline: Tennessee TBA/LSU TBA
  • Opening total: Over/Under 46 points scored
  • Time: 3:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: Tennessee (8-2 SU/6-4 ATS) kept itself firmly in the CFP chase with a big Week 11 road win. The Vols were 1.5-point favorites vs. Texas A&M and pulled away in the fourth quarter for a 22-7 victory.

Tennessee is 5-1 SU/4-2 ATS in its last six games.

LSU (6-4 SU/4-6 ATS) saw its CFP hopes vaporized in the waning seconds vs. Texas. Leading 21-16, the Tigers gave up a touchdown with just 3 seconds remaining to lose 22-21 as 5-point home favorites.

It was LSU's second straight loss, both at home and both as chalk. The Tigers were 6-point home favorites vs. Alabama and tumbled 31-13 in Week 10.

LSU-Tennessee opened at pick 'em in Circa Sports' college football odds Week 12. Within a minute Sunday afternoon, the number inched to LSU -1.

Georgia vs. South Carolina Odds

  • Opening point spread: Georgia -17
  • Opening moneyline: Georgia TBA/South Carolina TBA
  • Opening total: Over/Under 50.5 points scored
  • Time: 7:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: No. 1 Georgia (9-1 SU/8-2 ATS) is coming off its third straight blowout win and cover. The Bulldogs raced to a 31-0 second-quarter lead and pounded Missouri 48-21 laying 16.5 points at home.

South Carolina (6-4 SU/5-5 ATS) found itself on the wrong side of a blowout, and as the favorite, no less. The Gamecocks got trucked by Arkansas 34-6 as 6.5-point road faves. That ended a four-game SU and ATS upswing, while also killing South Carolina's CFP chances.

Georgia opened as hefty 17-point road chalk in Circa Sports' college football Week 12 odds, with no early movement.

SMU vs. Notre Dame

  • Opening point spread: Notre Dame -20.5
  • Opening moneyline: Notre Dame TBA/SMU TBA
  • Opening total: Over/Under 58 points scored
  • Time: 7:30 p.m. ET Saturday (NBC)

OPENING ODDS UPDATE: Notre Dame (9-1 SU/5-5 ATS) suffered zero letdown from its emotional Week 10 win over Miami. In Week 11, the Fighting Irish built a 31-0 halftime lead en route to a 41-7 blasting of Boston College as 29.5-point road favorites.

SMU (7-3 SU/4-5-1 ATS) actually closed as a 2.5-point home favorite vs. Wake Forest in Week 11. Then the Mustangs got blistered 42-0 in the first half en route to a 49-7 loss.

Notre Dame opened as nearly a three-touchdown favorite in Circa's Week 12 college football odds, at -20.5. There was no early movement. However, the total went straight from 58 to 56.5 within a few minutes.

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Patrick Everson

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson
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