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Featured Last Updated Nov 26 2025, 10:04 AM

NFL: Packers vs. Lions, Prediction, Odds

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
NFL: Packers vs. Lions, Prediction, Odds

Featured Image Credit: Junfu Han via Imagn Images

GB @ DET Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Green Bay Packers 305 Packers
+2.5 -105 +1.5 -110 + +2.5 -110 + +1.5 -115 + +1.5 -107 + +1.5 -115 + +1.5 -110 + +1.5 -105 + +1.5 -122 + +2.5 even  
Detroit Lions 306 Lions
-2.5 -115 -1.5 -110 + -2.5 -110 + -1.5 -105 + -1.5 -113 + -1.5 -105 + -1.5 -110 + -1.5 -115 + -1.5 -103 + -2.5 -120  
Green Bay Packers 305 Packers
o48.5 -110 o24 -110 + o24.5 -102 + o24.5 -102 + o24 -107 + o24.5 +115 + o24.5 +105 + o24.5 +105 + o24.5 +104 + o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u24 -110 + u24.5 -118 + u24.5 -118 + u24 -113 + u24.5 -135 + u24.5 -125 + u24.5 -125 + u24.5 -132 + u48.5 -110  
Green Bay Packers 305 Packers
+120 +120 + +125 + +114 + +120 + +120 + N/A +125 + +110 + +124  
Detroit Lions 306 Lions
-142 -140 + -150 + -135 + -143 + -146 + N/A -150 + -137 + -148  
Green Bay Packers 305 Packers
+2.5 -105 +0.5 -140 + +0.5 -145 + +0.5 -142 + N/A +1.5 -160 + +0.5 -145 + +1.5 -150 + +1.5 -165 + +2.5 even  
Detroit Lions 306 Lions
-2.5 -115 -0.5 +120 + -0.5 +110 + -0.5 +120 + N/A -1.5 +128 + -0.5 +120 + -1.5 +125 + -1.5 +130 + -2.5 -120  
Green Bay Packers 305 Packers
o48.5 -110 o9.5 -115 + o9.5 -135 + o9.5 -115 + N/A o9.5 -118 + o9.5 -115 + o8.5 -140 + o9.5 -121 + o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u9.5 -105 + u9.5 +105 + u9.5 -105 + N/A u9.5 -102 + u9.5 -105 + u8.5 +105 + u9.5 -103 + u48.5 -110  
Green Bay Packers 305 Packers
+120 +115 + +115 + +114 + N/A +112 + N/A +110 + +105 + +124  
Detroit Lions 306 Lions
-142 -135 + -145 + -135 + N/A -138 + N/A -145 + -130 + -148  
Green Bay Packers 305 Packers
+2.5 -105 +0.5 -110 + N/A +1.5 -135 + N/A +1.5 -125 + N/A N/A +1.5 -129 + +2.5 even  
Detroit Lions 306 Lions
-2.5 -115 -0.5 -110 + N/A -1.5 +105 + N/A -1.5 +110 + N/A N/A -1.5 +104 + -2.5 -120  
Green Bay Packers 305 Packers
o48.5 -110 o23.5 -110 + N/A o23.5 -108 + N/A o23.5 -100 + o23.5 -115 + N/A o23.5 -106 + o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u23.5 -110 + N/A u23.5 -112 + N/A u23.5 -120 + u23.5 -115 + N/A u23.5 -118 + u48.5 -110  
Green Bay Packers 305 Packers
+120 even + N/A even + N/A +108 + N/A N/A +107 + +124  
Detroit Lions 306 Lions
-142 -120 + N/A -130 + N/A -126 + N/A N/A -134 + -148  
Green Bay Packers 305 Packers
+2.5 -105 N/A N/A +0.5 -130 + N/A +1.5 -136 + +0.5 -125 + N/A N/A +2.5 even  
Detroit Lions 306 Lions
-2.5 -115 N/A N/A -0.5 even + N/A -1.5 +108 + -0.5 -105 + N/A N/A -2.5 -120  
Green Bay Packers 305 Packers
o48.5 -110 o14 -110 + N/A o14.5 -115 + N/A o14.5 -104 + o14.5 -110 + N/A N/A o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u14 -110 + N/A u14.5 -115 + N/A u14.5 -116 + u14.5 -120 + N/A N/A u48.5 -110  
Green Bay Packers 305 Packers
+120 +110 + N/A even + N/A +114 + N/A N/A N/A +124  
Detroit Lions 306 Lions
-142 -130 + N/A -130 + N/A -140 + N/A N/A N/A -148  
Green Bay Packers 305 Packers
+2.5 -105 N/A N/A +0.5 -154 + N/A +1.5 -170 + +0.5 -150 + N/A N/A +2.5 even  
Detroit Lions 306 Lions
-2.5 -115 N/A N/A -0.5 +120 + N/A -1.5 +140 + -0.5 +115 + N/A N/A -2.5 -120  
Green Bay Packers 305 Packers
o48.5 -110 o10 -105 + N/A o9.5 -130 + N/A o9.5 -110 + o9.5 -125 + N/A N/A o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u10 -115 + N/A u9.5 even + N/A u9.5 -108 + u9.5 -105 + N/A N/A u48.5 -110  
Green Bay Packers 305 Packers
+120 +105 + N/A -105 + N/A +102 + N/A N/A N/A +124  
Detroit Lions 306 Lions
-142 -125 + N/A -125 + N/A -122 + N/A N/A N/A -148  
Green Bay Packers 305 Packers
+2.5 -105 +0.5 -140 + N/A +0.5 -135 + N/A +1.5 -154 + +0.5 -115 + N/A N/A +2.5 even  
Detroit Lions 306 Lions
-2.5 -115 -0.5 +120 + N/A -0.5 +105 + N/A -1.5 +126 + -0.5 -115 + N/A N/A -2.5 -120  
Green Bay Packers 305 Packers
o48.5 -110 o13.5 -110 + N/A o13.5 -115 + N/A o13.5 -104 + o13.5 -110 + N/A N/A o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u13.5 -110 + N/A u13.5 -115 + N/A u13.5 -116 + u13.5 -120 + N/A N/A u48.5 -110  
Green Bay Packers 305 Packers
+120 -105 + N/A -105 + N/A +102 + N/A N/A N/A +124  
Detroit Lions 306 Lions
-142 -115 + N/A -125 + N/A -124 + N/A N/A N/A -148  

The Packers will take on the Lions in this week's NFL action. Kickoff is set for 1:00 p.m. EST at Ford Field in Detroit, Mich. The game will be broadcast live on FOX. Here's everything you need to know about Packers vs. Lions odds, the latest NFL spreads, NFL over/unders and more.

The Lions opened as a -2.5 point favorite over Packers. The total is set at over/under 48.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 11/26/25

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Green Bay Packers vs. Detroit Lions Best Bet

Revenge game from week 1 when the Packers pantsed them makes me want to be on Detroit. Trying to get ahead of the line move here. Love the even 3 sitting out there, worth a purchase before the Lions love rolls in.

Packers vs. Lions Best Bet: Lions -3

(Pick from Brandon Kravitz)

Looking for more best bets? Check out our free NFL picks and our premium subscription for the best picks!

What Time is the Green Bay Packers vs. Detroit Lions Game?

The Green Bay Packers vs. Detroit Lions game is at 1:00 PM ET on Thursday, November 27th.

Where is the Green Bay Packers vs. Detroit Lions Game Being Played?

This game will be played at Ford Field in Detroit, Michigan.

How Can I Watch Green Bay Packers vs. Detroit Lions?

You can watch Packers vs. Lions on FOX.

Can the Packers Beat the Lions?

Yes, the Packers will look to repeat their week 1 defeat of Detroit on Thanksgiving day.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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