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Featured Last Updated Nov 27 2025, 10:28 AM

NFL Week 13 Predictions: Thanksgiving Best Bets

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
NFL Week 13 Predictions: Thanksgiving Best Bets

Image Credit: Junfu Han / USA TODAY NETWORK via Imagn Images

Here are my NFL Week 13 predictions, including two picks for Thanksgiving day. I will be updating this throughout the holiday, so be sure to click the image below to add VegasInsider to your preferred sources.

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The best way to take advantage of NFL Week 13 lines is to ensure you are getting the best NFL odds. Our odds screen compiles odds from major books for every NFL game. You also need to be sure to claim relevant sportsbook promos to get the most bonus bets. Whether it is the bet365 bonus code, a Fanatics Sportsbook promo, or our FanDuel promo code, be sure to get in on the action with the best new user promos!

LIONS VS. PACKERS PREDICTION

GB @ DET Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Green Bay Packers 305 Packers
+2.5 -105 +2 -110 +2.5 -105 +0.5 -105 +1.5 -136 +1.5 -115 +1.5 -110 +1.5 -105 +1.5 -118 +2.5 +105  
Detroit Lions 306 Lions
-2.5 -115 -2 -110 -2.5 -115 -0.5 -115 -1.5 +106 -1.5 -105 -1.5 -120 -1.5 -115 -1.5 -106 -2.5 -125  
Green Bay Packers 305 Packers
o48.5 -110 o24 -105 o23.5 -118 o24.5 -105 o24.5 even o24.5 +110 o23.5 -125 o24.5 +105 o23.5 -114 o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u24 -115 u23.5 even u24.5 -115 u24.5 -127 u24.5 -130 u23.5 -105 u24.5 -125 u23.5 -109 u48.5 -110  
Green Bay Packers 305 Packers
+120 +125 +125 +114 +108 +126 N/A +125 +116 +130  
Detroit Lions 306 Lions
-142 -150 -150 -135 -137 -154 N/A -150 -143 -155  
Green Bay Packers 305 Packers
+2.5 -105 +0.5 -130 +0.5 -135 +0.5 -125 N/A +1.5 -152 +0.5 -140 +1.5 -140 +1.5 -157 +2.5 +105  
Detroit Lions 306 Lions
-2.5 -115 -0.5 +110 -0.5 +105 -0.5 +105 N/A -1.5 +124 -0.5 +110 -1.5 +115 -1.5 +125 -2.5 -125  
Green Bay Packers 305 Packers
o48.5 -110 o9.5 -120 o9.5 -125 o9.5 -112 N/A o9.5 -118 o9.5 -125 o8.5 -140 o9.5 -132 o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u9.5 even u9.5 -102 u9.5 -108 N/A u9.5 -104 u9.5 -105 u8.5 +105 u9.5 +106 u48.5 -110  
Green Bay Packers 305 Packers
+120 +120 +115 +124 N/A +116 N/A +120 +110 +130  
Detroit Lions 306 Lions
-142 -140 -145 -148 N/A -140 N/A -160 -136 -155  
Green Bay Packers 305 Packers
+2.5 -105 +0.5 -110 N/A +1.5 -125 N/A +1.5 -120 N/A N/A +1.5 -125 +2.5 +105  
Detroit Lions 306 Lions
-2.5 -115 -0.5 -110 N/A -1.5 -105 N/A -1.5 -100 N/A N/A -1.5 +102 -2.5 -125  
Green Bay Packers 305 Packers
o48.5 -110 o23.5 -110 N/A o23.5 -112 N/A o23.5 -105 o23.5 -125 N/A o23.5 -117 o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u23.5 -110 N/A u23.5 -108 N/A u23.5 -115 u23.5 -105 N/A u23.5 -107 u48.5 -110  
Green Bay Packers 305 Packers
+120 +105 N/A +114 N/A +112 N/A N/A +108 +130  
Detroit Lions 306 Lions
-142 -125 N/A -145 N/A -130 N/A N/A -136 -155  
Green Bay Packers 305 Packers
+2.5 -105 N/A N/A +0.5 -140 N/A +1.5 -128 +0.5 -120 N/A N/A +2.5 +105  
Detroit Lions 306 Lions
-2.5 -115 N/A N/A -0.5 +110 N/A -1.5 +104 -0.5 -110 N/A N/A -2.5 -125  
Green Bay Packers 305 Packers
o48.5 -110 o14 -110 N/A o15.5 -115 N/A o14.5 -104 o14.5 even N/A N/A o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u14 -110 N/A u15.5 -115 N/A u14.5 -118 u14.5 -130 N/A N/A u48.5 -110  
Green Bay Packers 305 Packers
+120 +120 N/A -115 N/A +118 N/A N/A N/A +130  
Detroit Lions 306 Lions
-142 -140 N/A -115 N/A -140 N/A N/A N/A -155  
Green Bay Packers 305 Packers
+2.5 -105 N/A N/A +0.5 -145 N/A +1.5 -166 +0.5 -150 N/A N/A +2.5 +105  
Detroit Lions 306 Lions
-2.5 -115 N/A N/A -0.5 +114 N/A -1.5 +134 -0.5 +115 N/A N/A -2.5 -125  
Green Bay Packers 305 Packers
o48.5 -110 o10 -105 N/A o9.5 -130 N/A o9.5 -120 o9.5 -130 N/A N/A o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u10 -115 N/A u9.5 even N/A u9.5 -110 u9.5 even N/A N/A u48.5 -110  
Green Bay Packers 305 Packers
+120 +105 N/A +105 N/A +104 N/A N/A N/A +130  
Detroit Lions 306 Lions
-142 -125 N/A -135 N/A -128 N/A N/A N/A -155  
Green Bay Packers 305 Packers
+2.5 -105 +0.5 -135 N/A -0.5 +114 N/A +1.5 -156 +0.5 -120 N/A N/A +2.5 +105  
Detroit Lions 306 Lions
-2.5 -115 -0.5 +115 N/A +0.5 -145 N/A -1.5 +126 -0.5 -110 N/A N/A -2.5 -125  
Green Bay Packers 305 Packers
o48.5 -110 o13.5 -110 N/A o13.5 -110 N/A o13.5 -102 o13.5 -125 N/A N/A o48.5 -110  
Detroit Lions 306 Lions
u48.5 -110 u13.5 -110 N/A u13.5 -120 N/A u13.5 -118 u13.5 -105 N/A N/A u48.5 -110  
Green Bay Packers 305 Packers
+120 even N/A -120 N/A +102 N/A N/A N/A +130  
Detroit Lions 306 Lions
-142 -120 N/A -110 N/A -122 N/A N/A N/A -155  

Jared Goff has a reputation as a dome merchant, but did you know he is also a Thanksgiving merchant? Jared Goff has thrown for 8 touchdowns and 0 interceptions in his career on turkey day. This is the 23rd time the Packers and the Lions have met on Thanksgiving, and the Lions are 12-9-1 in the first 22 matchups.

The Lions defense is extremely efficient when it comes to tackling. Detroit's defense has recorded a missed tackle rate of 8.7% and has allowed 305 yards due to missed tackles this season. Both of these marks are the lowest in the NFL.

Lions come out victorious on Thanksgiving.

Prediction: Detroit Lions -2.5 (-115)

RAVENS VS. BENGALS PREDICTION

CIN @ BAL Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Cincinnati Bengals 309 Bengals
+5.5 -110 +4 -110 + +3.5 -102 + +3.5 even + +4 -104 + +5.5 -110 + +4.5 -115 + +3.5 -105 + +4.5 -113 + +7 even  
Baltimore Ravens 310 Ravens
-5.5 -110 -4 -110 + -3.5 -118 + -3.5 -120 + -4 -117 + -5.5 -110 + -4.5 -105 + -3.5 -135 + -4.5 -110 + -7 -120  
Cincinnati Bengals 309 Bengals
o49.5 -110 o26 -115 + o26.5 -105 + o26.5 -102 + o26.5 -104 + o26.5 -110 + o26.5 -105 + o26.5 -105 + o26.5 -114 + o51.5 -115  
Baltimore Ravens 310 Ravens
u49.5 -110 u26 -105 + u26.5 -115 + u26.5 -118 + u26.5 -117 + u26.5 -110 + u26.5 -115 + u26.5 -115 + u26.5 -109 + u51.5 -105  
Cincinnati Bengals 309 Bengals
+185 +200 + +195 + +190 + +205 + +235 + N/A +200 + +225 + +300  
Baltimore Ravens 310 Ravens
-225 -245 + -235 + -225 + -260 + -300 + N/A -250 + -286 + -375  
Cincinnati Bengals 309 Bengals
+5.5 -110 +3 -120 + +1.5 -110 + +2.5 -108 + N/A +2.5 -110 + +2.5 -105 + +1.5 -105 + +2.5 -108 + +7 even  
Baltimore Ravens 310 Ravens
-5.5 -110 -3 even + -1.5 -118 + -2.5 -112 + N/A -2.5 -110 + -2.5 -115 + -1.5 -115 + -2.5 -114 + -7 -120  
Cincinnati Bengals 309 Bengals
o49.5 -110 o10 -105 + o9.5 -165 + o9.5 -148 + N/A o10.5 +124 + o9.5 -155 + o10.5 +125 + o10.5 +130 + o51.5 -115  
Baltimore Ravens 310 Ravens
u49.5 -110 u10 -115 + u9.5 +130 + u9.5 +124 + N/A u10.5 -150 + u9.5 +130 + u10.5 -170 + u10.5 -165 + u51.5 -105  
Cincinnati Bengals 309 Bengals
+185 +175 + +160 + +170 + N/A +164 + N/A +165 + +170 + +300  
Baltimore Ravens 310 Ravens
-225 -210 + -210 + -198 + N/A -215 + N/A -225 + -215 + -375  
Cincinnati Bengals 309 Bengals
+5.5 -110 +4 -110 + N/A +4.5 -120 + N/A +3.5 -110 + N/A N/A +3.5 -110 + +7 even  
Baltimore Ravens 310 Ravens
-5.5 -110 -4 -110 + N/A -4.5 -110 + N/A -3.5 -110 + N/A N/A -3.5 -114 + -7 -120  
Cincinnati Bengals 309 Bengals
o49.5 -110 o24 -110 + N/A o25.5 -115 + N/A o24.5 -115 + o25.5 -115 + N/A o25.5 -107 + o51.5 -115  
Baltimore Ravens 310 Ravens
u49.5 -110 u24 -110 + N/A u25.5 -105 + N/A u24.5 -105 + u25.5 -115 + N/A u25.5 -117 + u51.5 -105  
Cincinnati Bengals 309 Bengals
+185 +170 + N/A +210 + N/A +180 + N/A N/A +180 + +300  
Baltimore Ravens 310 Ravens
-225 -205 + N/A -270 + N/A -225 + N/A N/A -230 + -375  
Cincinnati Bengals 309 Bengals
+5.5 -110 N/A N/A +2.5 -115 + N/A +3.5 -118 + +2.5 even + N/A N/A +7 even  
Baltimore Ravens 310 Ravens
-5.5 -110 N/A N/A -2.5 -115 + N/A -3.5 -104 + -2.5 -130 + N/A N/A -7 -120  
Cincinnati Bengals 309 Bengals
o49.5 -110 o15.5 -110 + N/A o15.5 -115 + N/A o16.5 -112 + o15.5 -120 + N/A N/A o51.5 -115  
Baltimore Ravens 310 Ravens
u49.5 -110 u15.5 -110 + N/A u15.5 -115 + N/A u16.5 -108 + u15.5 -110 + N/A N/A u51.5 -105  
Cincinnati Bengals 309 Bengals
+185 +165 + N/A +140 + N/A +180 + N/A N/A N/A +300  
Baltimore Ravens 310 Ravens
-225 -205 + N/A -180 + N/A -230 + N/A N/A N/A -375  
Cincinnati Bengals 309 Bengals
+5.5 -110 N/A N/A +2.5 -115 + N/A +1.5 -116 + +1.5 -120 + N/A N/A +7 even  
Baltimore Ravens 310 Ravens
-5.5 -110 N/A N/A -2.5 -115 + N/A -1.5 -104 + -1.5 -110 + N/A N/A -7 -120  
Cincinnati Bengals 309 Bengals
o49.5 -110 o10 -110 + N/A o10.5 even + N/A o10.5 +118 + o10.5 +110 + N/A N/A o51.5 -115  
Baltimore Ravens 310 Ravens
u49.5 -110 u10 -110 + N/A u10.5 -130 + N/A u10.5 -144 + u10.5 -140 + N/A N/A u51.5 -105  
Cincinnati Bengals 309 Bengals
+185 +160 + N/A +160 + N/A +148 + N/A N/A N/A +300  
Baltimore Ravens 310 Ravens
-225 -190 + N/A -210 + N/A -184 + N/A N/A N/A -375  
Cincinnati Bengals 309 Bengals
+5.5 -110 +2.5 -110 + N/A +2.5 -105 + N/A +1.5 -116 + +2.5 -105 + N/A N/A +7 even  
Baltimore Ravens 310 Ravens
-5.5 -110 -2.5 -110 + N/A -2.5 -125 + N/A -1.5 -106 + -2.5 -125 + N/A N/A -7 -120  
Cincinnati Bengals 309 Bengals
o49.5 -110 o14 -110 + N/A o14.5 even + N/A o13.5 -124 + o14.5 +105 + N/A N/A o51.5 -115  
Baltimore Ravens 310 Ravens
u49.5 -110 u14 -110 + N/A u14.5 -130 + N/A u13.5 +104 + u14.5 -135 + N/A N/A u51.5 -105  
Cincinnati Bengals 309 Bengals
+185 +150 + N/A +165 + N/A +142 + N/A N/A N/A +300  
Baltimore Ravens 310 Ravens
-225 -180 + N/A -210 + N/A -176 + N/A N/A N/A -375  

Lamar Jackson has had tons of success against the Bengals in his carer. As a starting quarterback, he is 10-1 against the Bengals. He has had this Bengals' defense's number and I expect that trend to continue on Thanksgiving.

Joe Burrow may be back, but the defense is the real story for this Cincinnati team. The Bengals have the 5th worst red zone conversion rate allowed, and they are the third worst defense on third down. Ravens roll on Thanksgiving night.

Prediction: Baltimore Ravens -7 (-105)

COMMANDERS VS. BRONCOS PREDICTION

DEN @ WAS Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Denver Broncos 481 Broncos
+2.5 -110 -3.5 even + -2.5 -130 + -3.5 +102 + -3 -112 + -3.5 -100 + -3.5 even + -2.5 -125 + -2.5 -130 + -5.5 -118  
Washington Commanders 482 Commanders
-2.5 -110 +3.5 -120 + +2.5 even + +3.5 -122 + +3 -108 + +3.5 -120 + +3.5 -120 + +2.5 +105 + +2.5 +105 + +5.5 -102  
Denver Broncos 481 Broncos
o46.5 -110 o21.5 -110 + o20.5 -115 + o21.5 -112 + o21.5 -115 + o22.5 -110 + o21.5 -110 + o22.5 -105 + o21.5 -115 + o43.5 -105  
Washington Commanders 482 Commanders
u46.5 -110 u21.5 -110 + u20.5 -105 + u21.5 -108 + u21.5 -105 + u22.5 -110 + u21.5 -110 + u22.5 -115 + u21.5 -108 + u43.5 -115  
Denver Broncos 481 Broncos
+110 -185 + -190 + -185 + -193 + -205 + N/A -190 + -195 + -285  
Washington Commanders 482 Commanders
-130 +155 + +154 + +154 + +158 + +166 + N/A +160 + +155 + +220  
Denver Broncos 481 Broncos
+2.5 -110 -0.5 +110 + -0.5 +105 + -0.5 +114 + N/A -1.5 +108 + -0.5 +110 + -0.5 +105 + -1.5 +106 + -5.5 -118  
Washington Commanders 482 Commanders
-2.5 -110 +0.5 -130 + +0.5 -135 + +0.5 -135 + N/A +1.5 -130 + +0.5 -130 + +0.5 -125 + +1.5 -130 + +5.5 -102  
Denver Broncos 481 Broncos
o46.5 -110 o7.5 +105 + o7.5 -105 + o7.5 +105 + N/A o7.5 -110 + o7.5 -105 + o8.5 -105 + o7.5 -110 + o43.5 -105  
Washington Commanders 482 Commanders
u46.5 -110 u7.5 -125 + u7.5 -120 + u7.5 -125 + N/A u7.5 -112 + u7.5 -115 + u8.5 -125 + u7.5 -113 + u43.5 -115  
Denver Broncos 481 Broncos
+110 -155 + -160 + -155 + N/A -170 + N/A -170 + -167 + -285  
Washington Commanders 482 Commanders
-130 +130 + +130 + +130 + N/A +138 + N/A +130 + +135 + +220  
Denver Broncos 481 Broncos
+2.5 -110 -2.5 -115 + N/A -3.5 even + N/A -2.5 -125 + N/A N/A -2.5 -122 + -5.5 -118  
Washington Commanders 482 Commanders
-2.5 -110 +2.5 -105 + N/A +3.5 -130 + N/A +2.5 +105 + N/A N/A +2.5 even + +5.5 -102  
Denver Broncos 481 Broncos
o46.5 -110 o21.5 -110 + N/A o20.5 -118 + N/A o20.5 -110 + N/A N/A o20.5 -113 + o43.5 -105  
Washington Commanders 482 Commanders
u46.5 -110 u21.5 -110 + N/A u20.5 -102 + N/A u20.5 -110 + N/A N/A u20.5 -110 + u43.5 -115  
Denver Broncos 481 Broncos
+110 -160 + N/A -210 + N/A -194 + N/A N/A -186 + -285  
Washington Commanders 482 Commanders
-130 +135 + N/A +160 + N/A +162 + N/A N/A +148 + +220  
Denver Broncos 481 Broncos
+2.5 -110 N/A N/A -1.5 -115 + N/A -2.5 -110 + N/A N/A N/A -5.5 -118  
Washington Commanders 482 Commanders
-2.5 -110 N/A N/A +1.5 -115 + N/A +2.5 -110 + N/A N/A N/A +5.5 -102  
Denver Broncos 481 Broncos
o46.5 -110 o13 -105 + N/A o13.5 even + N/A o13.5 -104 + N/A N/A N/A o43.5 -105  
Washington Commanders 482 Commanders
u46.5 -110 u13 -115 + N/A u13.5 -130 + N/A u13.5 -116 + N/A N/A N/A u43.5 -115  
Denver Broncos 481 Broncos
+110 -190 + N/A -180 + N/A -178 + N/A N/A N/A -285  
Washington Commanders 482 Commanders
-130 +160 + N/A +135 + N/A +144 + N/A N/A N/A +220  
Denver Broncos 481 Broncos
+2.5 -110 N/A N/A -0.5 -110 + N/A -1.5 -102 + N/A N/A N/A -5.5 -118  
Washington Commanders 482 Commanders
-2.5 -110 N/A N/A +0.5 -120 + N/A +1.5 -118 + N/A N/A N/A +5.5 -102  
Denver Broncos 481 Broncos
o46.5 -110 o9.5 -110 + N/A o8.5 -120 + N/A o7.5 -110 + N/A N/A N/A o43.5 -105  
Washington Commanders 482 Commanders
u46.5 -110 u9.5 -110 + N/A u8.5 -110 + N/A u7.5 -110 + N/A N/A N/A u43.5 -115  
Denver Broncos 481 Broncos
+110 -165 + N/A -175 + N/A -184 + N/A N/A N/A -285  
Washington Commanders 482 Commanders
-130 +140 + N/A +135 + N/A +148 + N/A N/A N/A +220  
Denver Broncos 481 Broncos
+2.5 -110 -0.5 even + N/A -0.5 -120 + N/A -1.5 +104 + N/A N/A N/A -5.5 -118  
Washington Commanders 482 Commanders
-2.5 -110 +0.5 -120 + N/A +0.5 -110 + N/A +1.5 -126 + N/A N/A N/A +5.5 -102  
Denver Broncos 481 Broncos
o46.5 -110 o12.5 -115 + N/A o12.5 -115 + N/A o11.5 -114 + N/A N/A N/A o43.5 -105  
Washington Commanders 482 Commanders
u46.5 -110 u12.5 -105 + N/A u12.5 -115 + N/A u11.5 -108 + N/A N/A N/A u43.5 -115  
Denver Broncos 481 Broncos
+110 -140 + N/A -166 + N/A -158 + N/A N/A N/A -285  
Washington Commanders 482 Commanders
-130 +120 + N/A +130 + N/A +128 + N/A N/A N/A +220  

According to the Action Network's luck rankings, the Broncos have been one of the luckiest teams this season, whereas the Commanders have been one of the unluckiest. This alone implies that some regression is due both ways.

The Commanders are one of the best offenses in the red zone, converting touchdowns on 71.4% of trips. That is 2nd only to the Philadelphia Eagles. Even with Marcus Mariota, the Commanders are poised to keep this game closer than the point spread indicates.

Check out my complete Commanders vs. Broncos prediction.

Prediction: Washington Commanders +6.5 (-102)

TEXANS VS. COLTS PREDICTION

HOU @ IND Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Houston Texans 461 Texans
-1.5 -110 +2.5 even + +2.5 even + +2.5 -105 + +2.5 -104 + +3.5 -125 + +2.5 even + +1.5 +105 + +2.5 -107 + +3.5 -108  
Indianapolis Colts 462 Colts
+1.5 -110 -2.5 -120 + -2.5 -120 + -2.5 -115 + -2.5 -114 + -3.5 +105 + -2.5 -120 + -1.5 -125 + -2.5 -117 + -3.5 -112  
Houston Texans 461 Texans
o44.5 -110 o21.5 -115 + o22.5 -110 + o22.5 -105 + o22.5 -107 + o23.5 +105 + o22.5 -115 + o22.5 -110 + o22.5 -124 + o44.5 -115  
Indianapolis Colts 462 Colts
u44.5 -110 u21.5 -105 + u22.5 -110 + u22.5 -115 + u22.5 -113 + u23.5 -125 + u22.5 -105 + u22.5 -110 + u22.5 even + u44.5 -105  
Houston Texans 461 Texans
-122 +145 + +145 + +140 + +148 + +154 + N/A +145 + +135 + +160  
Indianapolis Colts 462 Colts
+102 -170 + -180 + -170 + -179 + -194 + N/A -175 + -175 + -192  
Houston Texans 461 Texans
-1.5 -110 +0.5 -130 + +0.5 -130 + +0.5 -135 + N/A +1.5 -122 + +0.5 -120 + +1.5 -130 + +1.5 -130 + +3.5 -108  
Indianapolis Colts 462 Colts
+1.5 -110 -0.5 +110 + -0.5 even + -0.5 +114 + N/A -1.5 +102 + -0.5 even + -1.5 +110 + -1.5 +106 + -3.5 -112  
Houston Texans 461 Texans
o44.5 -110 o7.5 +105 + o7.5 even + o7.5 even + N/A o9.5 -108 + o7.5 -110 + o8.5 -105 + o9.5 -107 + o44.5 -115  
Indianapolis Colts 462 Colts
u44.5 -110 u7.5 -125 + u7.5 -130 + u7.5 -120 + N/A u9.5 -114 + u7.5 -110 + u8.5 -125 + u9.5 -115 + u44.5 -105  
Houston Texans 461 Texans
-122 +125 + +130 + +120 + N/A +144 + N/A +135 + +135 + +160  
Indianapolis Colts 462 Colts
+102 -150 + -165 + -142 + N/A -180 + N/A -175 + -167 + -192  
Houston Texans 461 Texans
-1.5 -110 +2 -110 + N/A +1.5 -115 + N/A +1.5 -125 + N/A N/A +1.5 -129 + +3.5 -108  
Indianapolis Colts 462 Colts
+1.5 -110 -2 -110 + N/A -1.5 -115 + N/A -1.5 +105 + N/A N/A -1.5 +102 + -3.5 -112  
Houston Texans 461 Texans
o44.5 -110 o21 -110 + N/A o22.5 -115 + N/A o21.5 -110 + o22.5 -115 + N/A o21.5 -107 + o44.5 -115  
Indianapolis Colts 462 Colts
u44.5 -110 u21 -110 + N/A u22.5 -105 + N/A u21.5 -110 + u22.5 -115 + N/A u21.5 -117 + u44.5 -105  
Houston Texans 461 Texans
-122 +120 + N/A +120 + N/A +112 + N/A N/A +107 + +160  
Indianapolis Colts 462 Colts
+102 -140 + N/A -154 + N/A -130 + N/A N/A -132 + -192  
Houston Texans 461 Texans
-1.5 -110 N/A N/A +0.5 -110 + N/A +1.5 -120 + +0.5 -110 + N/A N/A +3.5 -108  
Indianapolis Colts 462 Colts
+1.5 -110 N/A N/A -0.5 -120 + N/A -1.5 -104 + -0.5 -120 + N/A N/A -3.5 -112  
Houston Texans 461 Texans
o44.5 -110 o13 -110 + N/A o13.5 even + N/A o13.5 -118 + o13.5 even + N/A N/A o44.5 -115  
Indianapolis Colts 462 Colts
u44.5 -110 u13 -110 + N/A u13.5 -130 + N/A u13.5 -104 + u13.5 -130 + N/A N/A u44.5 -105  
Houston Texans 461 Texans
-122 +140 + N/A +130 + N/A +128 + N/A N/A N/A +160  
Indianapolis Colts 462 Colts
+102 -170 + N/A -166 + N/A -162 + N/A N/A N/A -192  
Houston Texans 461 Texans
-1.5 -110 N/A N/A +0.5 -145 + N/A +1.5 -174 + +0.5 -150 + N/A N/A +3.5 -108  
Indianapolis Colts 462 Colts
+1.5 -110 N/A N/A -0.5 +114 + N/A -1.5 +142 + -0.5 +115 + N/A N/A -3.5 -112  
Houston Texans 461 Texans
o44.5 -110 o9.5 -110 + N/A o9.5 -120 + N/A o8.5 -116 + o9.5 -115 + N/A N/A o44.5 -115  
Indianapolis Colts 462 Colts
u44.5 -110 u9.5 -110 + N/A u9.5 -110 + N/A u8.5 -106 + u9.5 -115 + N/A N/A u44.5 -105  
Houston Texans 461 Texans
-122 +115 + N/A +105 + N/A -104 + N/A N/A N/A +160  
Indianapolis Colts 462 Colts
+102 -135 + N/A -135 + N/A -118 + N/A N/A N/A -192  
Houston Texans 461 Texans
-1.5 -110 +0.5 -125 + N/A +0.5 -120 + N/A +1.5 -140 + N/A N/A N/A +3.5 -108  
Indianapolis Colts 462 Colts
+1.5 -110 -0.5 +105 + N/A -0.5 -110 + N/A -1.5 +116 + N/A N/A N/A -3.5 -112  
Houston Texans 461 Texans
o44.5 -110 o12.5 -110 + N/A o13.5 even + N/A o12.5 -108 + o12.5 -130 + N/A N/A o44.5 -115  
Indianapolis Colts 462 Colts
u44.5 -110 u12.5 -110 + N/A u13.5 -130 + N/A u12.5 -112 + u12.5 even + N/A N/A u44.5 -105  
Houston Texans 461 Texans
-122 +110 + N/A +114 + N/A +112 + N/A N/A N/A +160  
Indianapolis Colts 462 Colts
+102 -130 + N/A -145 + N/A -138 + N/A N/A N/A -192  

C.J. Stroud is expected to be back to complement this top-tier Texans defense. The Texans are amongst the Rams, Bengals, and Seahawks when it comes to the best defenses in the NFL, and they have arguably the best pass defense. The Texans have allowed the 2nd-lowest EPA/play and are 1st in dropback EPA allowed (-0.127).

There is a difference in the schedules these two teams have faced as well. PFF has the Colts schedule ranked 27th, whereas the Texans strength of schedule is ranked 13th. The Texans should keep this one close in Stroud's return.

Be sure to check out my complete Texans vs. Colts prediction.

Prediction: Houston Texans +4.5 (-105)

I would love to hear from you all. You can interact with me on Threads and best of luck this week.

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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