NFL Preseason Week 3 Odds: Lines, Spreads, Betting Trends on Biggest Games

Patrick Everson Sports Betting Expert

6 minute read

2025 NFL Preseason Odds Week 3

NFL preseason odds for Week 3 are on the board and getting some attention. As the final week for exhibition games arrives, interest is ramping up in hopes that some big-name starters take some snaps.

Will Aaron Rodgers take the field in the Pittsburgh Steelers vs. Carolina Panthers tilt? And will we get Lamar Jackson vs. Jayden Daniels in the Baltimore Ravens vs. Washington Commanders contest?

Here’s everything you need to know about the NFL odds Preseason Week 3 market: opening lines, spreads and betting trends for noteworthy games, as multiple oddsmakers provide insights on NFL Preseason Week 3 odds and action. Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

(Feature image: D. Ross Cameron/Imagn Images)

NFL Odds for Preseason Week 3's Biggest Games

Pittsburgh Steelers vs. Carolina Panthers Odds

• Opening point spread: Steelers -3
• Opening moneyline: Steelers TBA/Panthers TBA
• Opening total: Over/Under 35.5 points scored
• Time: 7 p.m. ET Thursday (NFL Network)

UPDATE 8 P.M. ET MONDAY: Aaron Rodgers has yet to make his debut for Pittsburgh, which is 1-1 SU and ATS in preseason play. In Week 2 Saturday, the Steelers lost to Tampa Bay 17-14 on a final-seconds field goal, failing to cover as 1.5-point road underdogs.

Carolina (0-2 SU and ATS) has gotten blown out in both its preseason games, with starting QB Bryce Young seeing limited action in both games. In Week 2 at Houston on Saturday, the Panthers mustered only a second-quarter field goal in a 20-3 loss catching 3 points.

This afternoon, The SuperBook opened the Steelers at -3 in the NFL odds preseason Week 3 market. Within an hour, the line jumped straight to Steelers -4.5, showing the volatility often found in exhibition games.

"We took a respected bet, which brought us up to 4.5," SuperBook risk manager Casey Degnon said.

The total opened and remains a tidy 35.5.

New England Patriots vs. New York Giants Odds

• Opening point spread: Giants -4
• Opening moneyline: Giants TBA/Patriots TBA
• Opening total: Over/Under 37.5 points scored
• Time: 8 p.m. ET Thursday (Prime)

UPDATE 8 P.M. ET MONDAY: It's likely not a battle of future playoff teams. But the quarterback situation, particularly with New York, makes this matchup intriguing.

Rookie Jaxson Dart has helped the Giants go 2-0 SU and ATS in preseason play. On Saturday night in Week 2, the Giants were 3-point "home" favorites against their stadium roommate New York Jets, and the G-Men rolled 31-12.

Dart completed 14 of 16 passes for 137 yards and a touchdown. Longtime NFL veteran Russell Wilson, an offseason acquisition, is still atop the Giants' depth chart. But the buzz is all around Dart.

New England is also 2-0 SU and ATS, with no QB controversy. Drake Maye, in his second season, is the no-doubt starter and has seen few preseason snaps thus far. In Week 2, the Patriots beat Minnesota 20-12 as 1.5-point road underdogs.

The spread and total are stable on The SuperBook's NFL preseason Week 3 odds board, still sitting at this afternoon's openers of Giants -4/37.5.

Minnesota Vikings vs. Tennessee Titans Odds

• Opening point spread: Titans -3
• Opening moneyline: Titans TBA/Vikings TBA
• Opening total: Over/Under 37 points scored
• Time: 8 p.m. ET Friday (CBS)

UPDATE 8 P.M. ET MONDAY: No. 1 overall draft pick Cam Ward saw time for Tennessee in both preseason games, starting in Week 1. It's likely he'll get a longer look this week. In Week 2 at Atlanta, the Titans won and covered 23-20 as 2.5-point favorites.

Minnesota (1-1 SU and ATS) has a new QB, as well, though J.J. McCarthy is actually in his second season. McCarthy missed all of last year with a knee injury and hasn't played yet in the preseason. In Week 2, the Vikings lost to New England 20-12 giving 1.5 points at home.

Vikings-Titans opened this afternoon at Tennessee -3 in preseason Week 3 NFL odds. There's been no movement so far. Ditto for the total of 37.

Chicago Bears vs. Kansas City Chiefs Odds

• Opening point spread: Chiefs -4.5
• Opening moneyline: Chiefs TBA/Bears TBA
• Opening total: Over/Under 39 points scored
• Time: 8:20 p.m. ET Friday

UPDATE 8 P.M. ET MONDAY: Kansas City (0-2 SU and ATS) hasn't played Patrick Mahomes so far, but perhaps he'll see a little time to close out the preseason. In Week 2, the Chiefs were 5.5-point 'pups at Seattle and lost 33-16.

Chicago (1-0-1 SU/2-0 ATS) is coming off what looks like an impressive win. But keep in mind, this is preseason, as evidenced by the Bears being 2.5-point favorites at Buffalo. Chicago ended up posting a 38-0 blowout victory.

Caleb Williams started and played two series, leading a touchdown drive on the first. Williams went 6 of 10 for 107 yards, throwing a short pass to Olamide Zaccheaus that turned into a 36-yard TD.

Kansas City opened -4.5 in NFL preseason Week 3 odds at The SuperBook, with a total of 39. There's been no movement on the spread or total in the first few hours, a recurring theme so far in Week 3.

"These other games have nothing to them yet. It's too early in the week for the recreational bettors, and there's not enough information out there for the sharp action," SuperBook risk manager Casey Degnon said.

Baltimore Ravens vs. Washington Commanders Odds

• Opening point spread: Ravens -2.5
• Opening moneyline: Ravens TBA/Commanders TBA
• Opening total: Over/Under 35.5 points scored
• Time: Noon ET Saturday

UPDATE 4:30 P.M. ET TUESDAY: Jayden Daniels, coming off a sensational Rookie of the Year campaign for Washington, saw his first preseason action in Week 2. Daniels played one possession vs. Cincinnati, throwing no passes but running for a 14-yard touchdown to tie the game at 7.

The Commanders (0-2 SU and ATS) took a 14-7 lead on their second possession, but ultimately lost 31-17 catching 3.5 points at home Monday night.

For the most part, Baltimore has been a preseason spread-covering machine under John Harbaugh. But the Ravens went 0-6 ATS across the last two exhibition campaigns. However, Baltimore is 2-0 SU and ATS this year, including Saturday's 31-13 win at Dallas in a pick 'em game.

Ravens QB Lamar Jackson hasn't played a down so far in the preseason, and that seems unlikely to change this week.

The SuperBook pegged Baltimore as 2.5-point chalk in the NFL odds preseason Week 3 market, with no movement so far. The total is also stable at 35.5.

Los Angeles Chargers vs. San Francisco 49ers Odds

• Opening point spread: 49ers -2.5
• Opening moneyline: 49ers TBA/Chargers TBA
• Opening total: Over/Under 37 points scored
• Time: 8:30 p.m. ET Saturday

UPDATE 8 P.M. ET MONDAY: Jim Harbaugh's Los Angeles outfit gets the benefit – or perhaps the misfortune – of four preseason games, having played in the July 31 Hall of Fame Game.

The Chargers (2-1 SU and ATS) are coming off 23-22 loss laying 8.5 points vs. the Los Angeles Rams on Saturday. Starting QB Justin Herbert played only the first possession, going 2 of 5 for 46 yards while leading the Bolts to a field goal.

Also on Saturday, Brock Purdy saw his first preseason action for San Francisco (1-1 SU and ATS). Purdy played one possession, going 5 of 7 for 66 yards in leading the 49ers to a field goal at Las Vegas. The Niners went on to win 22-19 as 4.5-point underdogs.

The Chargers-49ers line was a big mover in the first hour after it went up. San Fran opened -2.5, went straight to -4.5 40 minutes later, then a few minutes later advanced to -5. Much like the Steelers-Panthers matchup, professional money showed up early for this game.

"We took sharp action on the 49ers, driving us all the way up to -5," SuperBook risk manager Casey Degnon said.

The total hasn't moved off 37 in The SuperBook's NFL preseason Week 3 odds.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson