NFL Odds Week 7: Cardinals vs Seahawks Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Seahawks vs
Cardinals
-8.5 (-110)
+8.5 (-110)
o43.5 (-110)
u43.5 (-110)
-405
+320

A couple NFC West teams look to get on track in Week 7 of the NFL season as the Seahawks host the Cardinals. The odds show Seattle as a 7.5-point home favorite against Arizona. Catch all the action live from Lumen Field on Sunday, October 22 at 4:05 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for Week 7 Cardinals vs Seahawks: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

Arizona Cardinals vs Seattle Seahawks Odds

The Seahawks are sizable home favorites against the Cardinals. (Getty)
  • Opening point spread: Seahawks -8
  • Opening moneyline: Seahawks -400/Cardinals +300
  • Opening total: Over/Under 46 points scored
  • Time: 4:05 p.m. ET Sunday (FOX)

UPDATE 2 P.M. ET FRIDAY: The Seahawks slipped from -8 to -7.5 Monday at BetMGM, and the line hasn't budged since. Spread tickets are running 3/1 and spread money almost 5/1 on Seattle as the weekend approaches.

BetMGM's total went straight from 46.5 to 44.5 Monday and has also been stagnant since then. The Under is seeing 61% of bets, while 52% of cash is on the Over.

UPDATE 11 P.M. ET SUNDAY: Seattle saw its three-game SU and ATS upswing end in Cincinnati. The Seahawks lost 17-13 as 3-point road 'dogs.

Arizona got bettors' attention by proving competitive and covering in its first three games. But the Cards (1-5 SU/3-3 ATS) are now in a three-game SU and ATS rut. Arizona led the L.A. Rams 9-6 in a first-half field-goal fest, but didn't score again in a 26-9 loss as a 7-point road underdog.

The SuperBook pegged Seattle -8 to open tonight and within an hour moved to Seahawks -8.5.

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 7 Report containing spreads, lines, and trends for every NFL matchup.

Cardinals vs Seahawks Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

This looks like a high line in a division battle, but it's not high enough. The market hasn't caught up to Arizona's regression after that frisky start, nor to how well Seattle has been playing.

The Seahawks offense ranks top 10 both running and passing by many metrics and should have its way against Arizona, and now Seattle's defense is catching up too, right as the Cards' offense has gone in the tank without James Conner.

Seattle is good! The Seahawks probably should've beaten the Bengals, and they rank bottom five in red zone offense and third down defense, two metrics key to winning but typically more random over time. Seattle should look even better as those numbers even out, and it might start here against Arizona.

Seattle already has comfortable double-digit wins against the Panthers and Giants, and that's what I think this line ought to be. Instead, this line is still identical to its preseason open and hasn't adjusted enough to what we've seen from either of these teams.

Pick: Seahawks -7.5 (-110)

For more NFL picks, check out Action Network's NFL Week 7: How to Bet Every Game & Every Team.

The One Stat to Know About Cardinals vs Seahawks

Action Network NFL researcher Evan Abrams offers his top betting stat:

The Cardinals have struggled vs. NFC West recently. They are 1-10 ATS in their last 11 games in the division. The Cardinals only have one road win in the last calendar year (1-8 SU).

For more NFL betting stats, check out Action Network's NFL Week 7 Betting Trends, Stats, Notes.

Where to place a bet this NFL Season?

  • Use our exclusive BetMGM Bonus Code VIBONUS1500 to unlock BetMGM’s welcome offer for new sportsbook users!
  • Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
  • Check out the North Carolina Sportsbooks just before they launch legal online sports betting.