Saints vs. Giants Predictions: Surprisingly High-Scoring NFC Affair
Updated on 10/15/26
The New Orleans Saints will take on the New York Giants in this week's NFL action. Kickoff is set for 1:00 PM EST at MetLife Stadium in East Rutherford, NJ. The game will be broadcast live on FOX. Here's everything you need to know about Saints vs. Giants odds, the latest NFL spreads, NFL over/unders and more.
Saints @ Giants Betting Odds
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open |  › |  › |  › |  › |  › |  › |  › |  › |  | ||
 275 Saints | +2.5 -105 | -1.5 +102 | -1 -105 | -1.5 even | -1.5 +101 | -1.5 -100 | -1 -105 | +0.5 -115 | PK -109 | -1.5 even | |
 276 Giants | -2.5 -115 | +1.5 -122 | +1 -112 | +1.5 -120 | +1.5 -121 | +1.5 -122 | +1 -115 | -0.5 -105 | PK -110 | +1.5 -120 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 275 Saints | o45.5 -110 | o45.5 -111 | o46 -108 | o45.5 -112 | o46 -110 | o45.5 -110 | o45.5 -110 | o46 -110 | o45.5 -109 | o45.5 -112 | |
| 276 Giants | u45.5 -110 | u45.5 -109 | u46 -110 | u45.5 -108 | u46 -110 | u45.5 -110 | u45.5 -110 | u46 -110 | u45.5 -112 | u45.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 275 Saints | +124 | -115 | -112 | -112 | -113 | -112 | -115 | -115 | -110 | -112 | |
| 276 Giants | -148 | -105 | -105 | -108 | -105 | -104 | -105 | -105 | -108 | -108 | |
The New Orleans Saints opened as a -1.5 point favorite to New York. The total is set at over/under 45.5 total points scored by both teams combined.
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Saints vs. Giants Prediction
Both of these teams rank in the top 6 of plays per game, with the Giants running over 65 plays per game and the Saints averaging nearly 67 offensive plays per game.
The Giants are surprisingly efficient in the passing game, ranking 12th in dropback EPA.
Both of these offenses have left a lot to be desired this season. The Saints rank 27th in EPA allowed and the Giants rank 22nd in EPA allowed. This could be a surprisingly high-scoring NFC affair.
Saints vs Giants Prediction: New Orleans Saints @ New York Giants o46 (-108)
(Pick from Dylan Wilkerson)
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