Atlanta Falcons vs. Carolina Panthers Picks, Predictions, Odds

Michael Crosson Sports Betting Expert

3 minute read

Week 10 of the NFL season will begin on Thursday night with a meaningful NFC South clash between the Atlanta Falcons and Carolina Panthers. Coverage begins from Bank of America Stadium in Charlotte at 8:15 p.m. ET on Amazon Prime.

Updated on 03/17/2026

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ATLANTA FALCONS vs. CAROLINA PANTHERS BETTING PREDICTION

The Falcons strung together a surprisingly solid first half of the season, as Atlanta opened with a modest 4-5 stretch consisting of wins over the Seahawks, Browns, Niners, Panthers, with four of their five losses coming by narrow margins of six points or less.

However, the key to Atlanta’s success has been offense thus far, as Marcus Mariota and co. currently rank 10^th in the league in scoring at 24.1 PPG, while defensively, they rank 26^th in points allowed at 25 PPG.

The Panthers, on the other hand, posted a very frustrating start with Baker Mayfield under center, as Carolina followed up last year’s 5-12 campaign with a similarly poor 2-7 skid to open this season, while ranking 23^rd in scoring and 30^th total offense during that span (19.9 PPG, 286 YPG).

I’ll take the over here, though, as the Panthers’ offense has cranked out a modest average of 25.3 PPG across their last three games with PJ Walker at the helm, while on the defensive side of the script, also surrendering 37+ PTS in two of those three affairs. Ultimately, setting the stage for a high-scoring battle against a Falcons squad that’s scored 26+ PTS in five-of-nine matchups this year, which already includes a 37-point outing against Carolina (W, 37-34).

Score Prediction: Falcons 27, Panthers 23
Best Bet: Over 43.5 (-110)

ATLANTA FALCONS vs. CAROLINA PANTHERS BETTING ODDS

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ATLANTA FALCONS vs. CAROLINA PANTHERS BETTING RESOURCES

Date: Thursday, November 10, 2022
Matchup: NFC South
Venue: Bank of America Stadium
Location: Charlotte, North Carolina
Time-TV: Amazon Prime, 8:15 p.m. ET

ATLANTA FALCONS BETTING ANALYSIS

The Panthers stumbled out to an incredibly disappointing start following the offseason acquisition of Mayfield, as Carolina averaged just 17.2 PPG and turned the ball over eight times across a miserable 1-5 skid to open, while scoring less than 17 PTS and allowing 24+ PTS in four affairs during that timeframe.

The Panthers haven’t exactly played well the last three weeks, especially on the defensive side of the ball, however, their offense has played surprisingly decent with PJ Walker at the helm since Week 7, highlighted by Carolina scoring 21+ PTS in three straight games heading into Thursday night’s tilt.

CAROLINA PANTHERS BETTING ANALYSIS

Nobody gave Atlanta much of a chance after posting a 7-10 record in Matt Ryan’s final campaign with the squad last year, as the Falcons entered this season with a win total OU of 4.5, which projected them for a last place finish in the division behind the Panthers with a line of OU 5.5 wins.

However, Atlanta enters Week 10 just one win away from clearing that number, as the Falcons currently find themselves tied for the division lead alongside the Bucs with a record of 4-5, with the lone differentiating factor between them being Tampa Bay’s 21-16 victory over Atlanta back in Week 5.

Atlanta’s highest scoring output of the season came in a 37-34 victory over Carolina back in Week 6, and while I’d love to use that as an excuse to back the Falcons in this contest, I simply can’t bring myself to do it after seeing them surrender 34 PTS to the Panthers with Walker under center just a few weeks ago.

ATLANTA FALCONS vs. CAROLINA PANTHERS BETTING TRENDS

• The Falcons are 6-3 ATS in their last nine games.
• The total has gone UNDER in four of Atlanta's last six games.
• The Panthers are 3-13 ATS in their last 16 games.
• The Panthers are 2-14 SU in their last 16 games.
• The total has gone UNDER in 13 of Carolina's last 19 games against Atlanta.
• The Panthers are 2-9 ATS in their last 11 home games.
• The Falcons are 10-4 ATS in their last 14 games against Carolina.
• The Falcons are 8-2 SU in their last 10 games against Carolina.
• The Falcons are 1-5 SU in their last six road games.
• The Falcons are 5-1 ATS in their last six games when playing on the road against Carolina.

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Michael Crosson

Michael Crosson began his time at VegasInsider as a freelance NBA writer back in 2019 while he continued to study Psychology and Biology at James Madison University. Following his graduation in 2021, Michael joined the team full-time, and he's been with VI ever since. Michael still writes NBA, NFL, and MLB for VI, as well as gambling industry news. He's also become a crucial part of our editorial production team. More from Michael Crosson