Eagles Odds
| Pos | Player | Status |
| WR | A.J. Brown (Hamstring) | Questionable |
| WR | A.J. Brown (Hamstring) | Out |
| WR | A.J. Brown (Hamstring) | Questionable |
| Date | Opp | Close | Result | ATS/OU |
| Sep 4, 2025 | Cowboys | -8.5
/ 47.5 | Won 24-20 | Lost /
Under |
| Sep 14, 2025 | @Chiefs | -1.5
/ 46.5 | Won 20-17 | Won /
Under |
| Sep 21, 2025 | Rams | -3.5
/ 45.5 | Won 33-26 | Won /
Over |
| Sep 28, 2025 | @Buccaneers | -3.5
/ 44.5 | Won 31-25 | Won /
Over |
| Oct 5, 2025 | Broncos | -4
/ 44.5 | Lost 17-21 | Lost /
Under |
| Oct 9, 2025 | @Giants | -7.5
/ 40.5 | Lost 17-34 | Lost /
Over |
| Oct 19, 2025 | @Vikings | -2.5
/ 44 | Won 28-22 | Won /
Over |
| Oct 26, 2025 | Giants | -7.5
/ 43.5 | Won 38-20 | Won /
Over |
| Nov 10, 2025 | @Packers | +1
/ 45 | Won 10-7 | Won /
Under |
| Nov 16, 2025 | Lions | -
/ | | 8:20 PM ET |
| Nov 23, 2025 | @Cowboys | -
/ | | 4:25 PM ET |
| Nov 28, 2025 | Bears | -
/ | | 3:00 PM ET |
| Dec 8, 2025 | @Chargers | -
/ | | 8:15 PM ET |
| Dec 14, 2025 | Raiders | -
/ | | 1:00 PM ET |
| Dec 20, 2025 | @Commanders | -
/ | | 11:00 AM ET |
| Dec 28, 2025 | @Bills | -
/ | | 4:25 PM ET |
| Jan 4, 2026 | Commanders | -
/ | | 1:00 PM ET |
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