2026 March Madness Odds: Lines, Spreads, Betting Trends for Final Four

Patrick Everson Sports Betting Expert

2 minute read

The March Madness Odds Final Four market is taking shape, with the first two contestants securing trips to Indianapolis.

No. 3 seed Illinois will have a spot on the 2026 Final Four odds board, opposite either No. 2 UConn or No. 1 Duke. Also advancing on Saturday was No. 1 Arizona, which awaits either No. 1 Michigan or No. 6 Tennessee.

Here's everything you need to know about college basketball odds for 2026 March Madness Final Four games: opening lines, spreads and betting trends. Check back for updates throughout the week, and use our BetMGM bonus code to get the most out of your action.

(Feature image: Maria Lysaker/Imagn Images)

March Madness Final Four Odds

Illinois vs. UConn-Duke Odds

• Opening point spread: TBA
• Opening moneyline: Illinois TBA/UConn-Duke TBA
• Opening total: Over/Under TBA points scored
• Time: TBA Saturday, April 4

OPENING ODDS UPDATE: After a slow start Saturday night, No. 3 Illinois (28-8 SU/20-16 ATS) ultimately got into a back-and-forth battle with upstart No. 9 seed Iowa. But the Fighting Illini pulled away late vs. their Big Ten rival, claiming a 71-59 victory as 6.5-point favorites.

With 7:27 remaining, the game was tied at 50. But the Illini finished with a 21-9 run in the South Region final. Illinois is 4-0 SU and ATS in the NCAA Tourney.

Up next for the Illini: The winner of Sunday's East Region final between No. 1 seed Duke (35-2 SU/21-16 ATS) and No. 2 UConn (32-5 SU/15-22 ATS). Check back Sunday for updates on March Madness Final Four odds, once this matchup is set.

Arizona vs. Tennessee/Michigan Odds

• Opening point spread: Arizona TBA
• Opening moneyline: Arizona TBA/Tennessee-Michigan TBA
• Opening total: Over/Under TBA points scored
• Time: TBA Saturday, April 4

OPENING ODDS UPDATE: No. 1 Arizona (36-2 SU/24-14 ATS) trailed No. 2 Purdue 38-31 at halftime Saturday night. But the Wildcats owned the second half and rolled to a 79-64 victory laying 5.5 points in the West Region final.

Arizona is on a 13-0 SU tear, going 9-4 ATS in that stretch.

The Wildcats face the winner of Sunday's Midwest Region final between No. 1 Michigan (34-3 SU/17-20 ATS) and No. 6 Tennessee (25-11 SU/17-19 ATS). Check back Sunday for updates on 2026 Final Four odds, once Arizona has an opponent.

NCAA Tournament Kalshi Odds

Prediction markets such as Kalshi are also involved with college basketball conference tournaments. Check out the Kalshi promo code before trading on NCAA Tournament futures odds:

• Michigan +317
• Duke +400
• Arizona +426
• Illinois +488
• Purdue +1150
• UConn +2400
• Tennessee +3233

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson