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Michigan State vs UNC Prediction | NCAA Tourney Second Round Picks & Odds

Kevin Rogers
Kevin Rogers Sports Betting Expert
2 minute read

The Second Round of NCAA Tourney begins on Saturday afternoon -- and the third matchup of the day we'll be breaking down is Michigan State vs UNC, which is scheduled for 5:30 p.m. ET on CBS.

The Tar Heels are 4-point favorites on the spread in Saturday's contest; with the game total stationed at over/under 140.5 at most sportsbooks.

Here's everything you need to know about Michigan State vs UNC -- our expert prediction and betting picks for this Second Round NCAA Tournament matchup on Saturday, March 23.

Michigan State vs UNC Odds

MSU @ UNC Odds

  • Full Game
  • 1H
  • Spread
  • Total
  • Moneyline
Final
Michigan State Spartans 789 Michigan State
+3.5 -115 +2.5 -115 N/A +2.5 -120 +2.5 -112 +2.5 -120 +2.5 -118 +3.5 -104  
North Carolina Tar Heels 790 North Carolina
-3.5 -105 -2.5 -105 N/A -2.5 -110 -2.5 -108 -2.5 -110 -2.5 -108 -3.5 -118  
Final
Michigan State Spartans 789 Michigan State
o144.5 -115 o67.5 -110 o66.5 -120 N/A o67.5 -110 o67.5 -115 o66.5 -114 o143.5 -104  
North Carolina Tar Heels 790 North Carolina
u144.5 -105 u67.5 -110 u66.5 -104 N/A u67.5 -110 u67.5 -115 u66.5 -112 u143.5 -118  
Final
Michigan State Spartans 789 Michigan State
+132 N/A N/A +135 +142 N/A +145 +150  
North Carolina Tar Heels 790 North Carolina
-160 N/A N/A -175 -170 N/A -177 -182  
Final
Michigan State Spartans 789 Michigan State
+3.5 -115 -0.5 -115 +1.5 -112 N/A N/A N/A +2 -114 +3.5 -104  
North Carolina Tar Heels 790 North Carolina
-3.5 -105 +0.5 -105 -1.5 -114 N/A N/A N/A -2 -112 -3.5 -118  
Final
Michigan State Spartans 789 Michigan State
o144.5 -115 o76.5 -110 o75.5 -116 N/A N/A N/A N/A o143.5 -104  
North Carolina Tar Heels 790 North Carolina
u144.5 -105 u76.5 -110 u75.5 -108 N/A N/A N/A N/A u143.5 -118  
Final
Michigan State Spartans 789 Michigan State
+132 N/A N/A N/A N/A N/A N/A +150  
North Carolina Tar Heels 790 North Carolina
-160 N/A N/A N/A N/A N/A N/A -182  

Michigan State vs UNC Picks & Prediction

The Spartans and Tar Heels last met in the NCAA Tournament back in 2009 in the title game.

North Carolina took care of Michigan State, 89-72 to capture the championship as the two legendary programs meet in the second round on Saturday.

UNC took care of 16th-seeded Wagner in the first round, marking the program's first tournament win since beating rival Duke in the 2022 Final Four.

Michigan State never trailed in Thursday's 69-51 blowout of Mississippi State as the Spartans limited the Bulldogs to 6-of-27 shooting from downtown.

The Tar Heels owned the best defensive efficiency numbers in ACC play, along with the top 2-point and 3-point percentage defense.

This line seems extremely short considering North Carolina is a top seed and Michigan State has lost five of its last eight games.

Pick: Michigan State +4 (-110)

Click this link for betting picks and predictions for all 16 Second Round matchups of the NCAA Tourney!

Michigan State vs UNC Game Time & TV Channel

Date: Saturday, March 23
Matchup: Big Ten vs ACC
Venue: Spectrum Center
Location: Charlotte, NC
Time-TV: CBS, 5:30 p.m. ET

Michigan State vs UNC Betting Stats

1) North Carolina Tar Heels
(ACC, At-Large)

  • Futures: +2000
  • Region: +260
  • SU: 27-7
  • ATS: 18-15-1
  • O/U: 16-18
  • PPG: 81.6
  • OPPG: 70.1

9) Michigan State Spartans
(Big Ten, At-Large)

  • Futures: +10000
  • Region: +1100
  • SU: 19-14
  • ATS: 18-14-1
  • O/U: 14-19
  • PPG: 73.4
  • OPPG: 65.9

March Madness Betting Resources

March Madness Second Round Odds

The NCAA Men's Tournament Second Round will take place on Saturday, March 23 and Sunday, March 24.

Check out the teams, odds, betting stats and much more on each of the four regions below:

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Kevin Rogers

Kevin Rogers

Kevin has been handicapping professionally since 2007 at VegasInsider before shifting to ScoresAndOdds. He focuses on MLB, NFL, college football, NBA, college basketball, and NHL and mainly uses trends, systems, and situations as his top handicapping angles. More from Kevin Rogers
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