Alabama vs. Missouri: Prediction, Odds, Best Bet

Alabama vs. Missouri: Prediction, Odds, Best Bet

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BAMA @ MIZ Odds

The Alabama Crimson Tide will take on the Missouri Tigers in this week's NCAAF action. Kickoff is set for 12:00 p.m. EDT at Memorial Stadium/Faurot Field in Columbia, Mo. The game will be broadcast live on ABC. Here's everything you need to know about Alabama vs. Missouri odds, the latest NCAAF spreads, NCAAF over/unders and more.

The Alabama Crimson Tide opened as a -3 point favorite over Missouri. The total is set at over/under 51.5 total points scored by both teams combined.

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Updated on 10/10/25

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Alabama vs. Missouri Best Bet

This Alabama defense remains vulnerable against the run and doesn't have the same elite talent along the defensive line that we became so accustomed to seeing under Nick Saban. On the season, the Tide rank outside the top 100 in sacks per game.

On the other side of the ball, Alabama has really struggled to get any consistent run game going (although it's better with Jam Miller back), which will allow Missouri's tremendous pass rush to get after Simpson, who hasn't seen a pass rush at this level yet.

Ty Simpson has played clean football with 13 touchdowns to just one interception, but he does have four turnover-worthy plays.

Ultimately, I just don't have a ton separating the top of the SEC from the next tier. Throw in the situation and some matchup advantages for the Tigers, and I like anything at a field goal or better against a Tide team that has certainly had its fair share of road woes in recent seasons.

Alabama vs. Missouri Best Bet: Missouri +3.5 (-110)

(Pick from Stuckey)

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What Time is the Alabama vs. Missouri Game?

The Alabama Crimson Tide will take on the Missouri Tigers at 12:00 ET on Saturday, October 11th.

Where is the Alabama Crimson Tide vs. Missouri Tigers Game Being Played?

This game is going to be played at Memorial Stadium in Columbia, MO.

How Can I Watch Alabama vs. Missouri?

You can watch Alabama vs. Missouri on ABC.

Can Missouri Beat Alabama?

Yes, considering the short spread, the Vegas oddsmakers are expecting a tight one in Columbia.