College Football Odds Week 4: Iowa vs Penn State Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Penn State vs
-14.5 (-104)
+14.5 (-118)
o38.5 (-105)
u38.5 (-115)

College football bettors are abuzz with anticipation as the odds for Week 4 hit the masses, yet again, immersing us in all of the weekend's crucial storylines. Penn State faces off against Iowa at Beaver Stadium in University Park on September 23 at 7:30 p.m. ET, and you can tune in to this one on CBS.

Here's everything you need to know about the college football odds for Week 4 Iowa vs. Penn State: the opening lines, spreads, betting trends and more. Check back regularly for updates.

No. 24 Iowa vs No. 7 Penn State Odds

  • Opening point spread: Penn State -14
  • Opening moneyline: Penn State -720/Iowa +450
  • Opening total: Over/Under 41.5 points scored
  • Time: 7:30 p.m. ET Saturday (CBS)

UPDATE 12:30 P.M. ET FRIDAY: Fanatics Sportsbook opened Penn State -14, peaked at -15 Wednesday and is now -14.5. It's two-way spread play with a lean toward Iowa, at 56% of tickets and money.

The total is down to 39.5 from a 41.5 opener and 42 high points. Ticket count is 2/1-plus on the Over, but money is just shy of 2/1 on the Under.

UPDATE 3:30 P.M. ET MONDAY: Penn State is out of the gate 3-0 SU and ATS. In Week 3, the Nittany Lions had little trouble in a 30-13 win laying 14.5 points at Illinois.

Iowa (3-0 SU/2-1 ATS) notched a 41-10 victory as 28.5-point home chalk vs. Western Michigan.

TwinSpires nudged Penn State from -14 to -14.5 in the college football odds Week 4 market. Iowa is actually getting 64% of early bets, while 61% of early money is on Penn State.

"Another Pros vs. Joes battle. Pros on Penn State -14," Lucas said.

The total hasn't moved off 41.5, with 59% of bets on the Over/56% of money on the Under.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 4 Report containing spreads, lines, and trends for every Top 25 matchup.