LSU vs. Vanderbilt: Prediction, Odds, Best Bet

Dylan Wilkerson Sports Betting Expert

8 minute read

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LSU @ Vanderbilt Betting Odds

• Spread
• Total
• Moneyline

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
Final	Open	›	›	›	›	›	›	›	›
365 LSU	-3.5 -110	+1.5 -110	+1.5 -110	+1.5 -112	+1.5 -110	+1.5 -108	+1.5 -110	+1.5 -110	+1.5 -113	+1.5 -112
366 Vanderbilt	+3.5 -110	-1.5 -110	-1.5 -110	-1.5 -108	-1.5 -110	-1.5 -112	-1.5 -110	-1.5 -110	-1.5 -110	-1.5 -108
Matchup
Final	Open	›	›	›	›	›	›	›	›
365 LSU	o49.5 -105	o48.5 -110	o48.5 -105	o48.5 -105	o48.5 -110	o48.5 -105	o48.5 -105	o48.5 -110	o47.5 -113	o48.5 -105
366 Vanderbilt	u49.5 -115	u48.5 -110	u48.5 -115	u48.5 -115	u48.5 -110	u48.5 -115	u48.5 -120	u48.5 -110	u47.5 -110	u48.5 -115
Matchup
Final	Open	›	›	›	›	›	›	›	›
365 LSU	-102	even	even	+102	even	-100	-105	even	-103	+102
366 Vanderbilt	-118	-120	-120	-122	-120	-120	-125	-120	-122	-122
Matchup

The LSU Tigers will take on the Vanderbilt Commodores in this week's college football action. Kickoff is set for 12:00 p.m. EDT at FirstBank Stadium in Nashville, Tenn. The game will be broadcast live on ABC. Here's everything you need to know about LSU vs. Vanderbilt odds, the latest college football spreads, college football over/unders and more.

The Vanderbilt Commodores opened as a -2.5 point favorite over LSU. The total is set at over/under 48.5 total points scored by both teams combined.

This game is featured in our college football week 8 best bets article. Check out the rest of my bets for saturday.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 3/4/26

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LSU vs. Vanderbilt Best Bet

While LSU's offense is having its offensive struggles, their defense has been extremely strong. This combination has led LSU to a 5-1 record to the under. Neither team is in a rush to get plays off, and even Vanderbilt's defense has flashed some promise. I am going to bet on LSU to continue their defensive dominance and offensive ineptitude.

LSU vs. Vanderbilt Best Bet: LSU Tigers @ Vanderbilt Commodores u49.5 (-112)

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(Pick from Dylan Wilkerson)

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What Time is the Vanderbilt vs. LSU Game?

The Commodores will take on the Tigers at 12:00 PM ET on Saturday, October 18th.

Where is the Vanderbilt vs. LSU Game Being Played?

This game is going to be played at FirstBank Stadium in Nashville, Tenn.

How Can I Watch The Vanderbilt vs. LSU Game?

You can watch Vanderbilt vs. LSU on ABC.

Can LSU Beat The Vanderbilt Commodores?

Absolutely! LSU is a slight underdog in this game. Anything can happen in college football!

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson