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Featured Last Updated Dec 2 2025, 11:18 AM

ACC Championship Prediction, Odds: Virginia vs. Duke

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
ACC Championship Prediction, Odds: Virginia vs. Duke

Image Credit: Zachary Taft-Imagn Images

DUKE @ UVA Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Duke Blue Devils 117 Duke
+2.5 -110 +1.5 -105 + +2.5 -110 + +2.5 -108 + +2.5 -110 + +2.5 -106 + +2.5 -115 + +2.5 -115 + +2.5 -110 + +3.5 -112  
Virginia Cavaliers 118 Virginia
-2.5 -110 -1.5 -115 + -2.5 -110 + -2.5 -112 + -2.5 -110 + -2.5 -114 + -2.5 -115 + -2.5 -115 + -2.5 -114 + -3.5 -108  
Duke Blue Devils 117 Duke
o57.5 -110 o27.5 -115 + o27.5 -115 + o27.5 -118 + o27.5 -118 + o29.5 -105 + o27.5 -120 + o27.5 -120 + o27.5 -114 + o57.5 -110  
Virginia Cavaliers 118 Virginia
u57.5 -110 u27.5 -105 + u27.5 -105 + u27.5 -102 + u27.5 -108 + u29.5 -115 + u27.5 -110 + u27.5 -110 + u27.5 -114 + u57.5 -110  
Duke Blue Devils 117 Duke
+110 +125 + +120 + +120 + +122 + +126 + N/A N/A +114 + +140  
Virginia Cavaliers 118 Virginia
-130 -150 + -145 + -142 + -150 + -150 + N/A N/A -150 + -166  
Duke Blue Devils 117 Duke
+2.5 -110 +0.5 -125 + +0.5 -130 + +0.5 -125 + N/A +1.5 -145 + +0.5 -130 + -0.5 +165 + +1.5 -148 + +3.5 -112  
Virginia Cavaliers 118 Virginia
-2.5 -110 -0.5 -105 + -0.5 even + -0.5 -105 + N/A -1.5 +116 + -0.5 +105 + +0.5 -225 + -1.5 +114 + -3.5 -108  
Duke Blue Devils 117 Duke
o57.5 -110 o13 -110 + o13.5 -105 + o12.5 -120 + N/A o13.5 -118 + o10.5 -125 + o13.5 even + o13.5 -108 + o57.5 -110  
Virginia Cavaliers 118 Virginia
u57.5 -110 u13 -120 + u13.5 -120 + u12.5 -110 + N/A u13.5 -106 + u10.5 -105 + u13.5 -130 + u13.5 -121 + u57.5 -110  
Duke Blue Devils 117 Duke
+110 +115 + +115 + +110 + N/A +114 + N/A N/A +110 + +140  
Virginia Cavaliers 118 Virginia
-130 -145 + -150 + -140 + N/A -146 + N/A N/A -143 + -166  
Duke Blue Devils 117 Duke
+2.5 -110 N/A N/A +1.5 -105 + N/A N/A N/A N/A N/A +3.5 -112  
Virginia Cavaliers 118 Virginia
-2.5 -110 N/A N/A -1.5 -115 + N/A N/A N/A N/A N/A -3.5 -108  
Duke Blue Devils 117 Duke
o57.5 -110 N/A N/A o28.5 -108 + N/A N/A o28.5 -105 + N/A N/A o57.5 -110  
Virginia Cavaliers 118 Virginia
u57.5 -110 N/A N/A u28.5 -112 + N/A N/A u28.5 -125 + N/A N/A u57.5 -110  
Duke Blue Devils 117 Duke
+110 N/A N/A +124 + N/A N/A N/A N/A N/A +140  
Virginia Cavaliers 118 Virginia
-130 N/A N/A -148 + N/A N/A N/A N/A N/A -166  
Duke Blue Devils 117 Duke
+2.5 -110 N/A N/A +0.5 -130 + N/A +1.5 -136 + N/A N/A N/A +3.5 -112  
Virginia Cavaliers 118 Virginia
-2.5 -110 N/A N/A -0.5 even + N/A -1.5 +102 + N/A N/A N/A -3.5 -108  
Duke Blue Devils 117 Duke
o57.5 -110 o16.5 -115 + N/A o16.5 -115 + N/A o16.5 -114 + N/A N/A N/A o57.5 -110  
Virginia Cavaliers 118 Virginia
u57.5 -110 u16.5 -115 + N/A u16.5 -115 + N/A u16.5 -110 + N/A N/A N/A u57.5 -110  
Duke Blue Devils 117 Duke
+110 +110 + N/A +105 + N/A +112 + N/A N/A N/A +140  
Virginia Cavaliers 118 Virginia
-130 -140 + N/A -135 + N/A -142 + N/A N/A N/A -166  
Duke Blue Devils 117 Duke
+2.5 -110 N/A N/A +0.5 -135 + N/A +1.5 -158 + N/A N/A N/A +3.5 -112  
Virginia Cavaliers 118 Virginia
-2.5 -110 N/A N/A -0.5 +105 + N/A -1.5 +120 + N/A N/A N/A -3.5 -108  
Duke Blue Devils 117 Duke
o57.5 -110 o13.5 -120 + N/A o13.5 -110 + N/A o12.5 -122 + N/A N/A N/A o57.5 -110  
Virginia Cavaliers 118 Virginia
u57.5 -110 u13.5 -110 + N/A u13.5 -120 + N/A u12.5 -102 + N/A N/A N/A u57.5 -110  
Duke Blue Devils 117 Duke
+110 +105 + N/A +110 + N/A +108 + N/A N/A N/A +140  
Virginia Cavaliers 118 Virginia
-130 -135 + N/A -140 + N/A -140 + N/A N/A N/A -166  
Duke Blue Devils 117 Duke
+2.5 -110 +0.5 -145 + N/A +0.5 -125 + N/A +1.5 -158 + N/A N/A N/A +3.5 -112  
Virginia Cavaliers 118 Virginia
-2.5 -110 -0.5 +115 + N/A -0.5 -105 + N/A -1.5 +118 + N/A N/A N/A -3.5 -108  
Duke Blue Devils 117 Duke
o57.5 -110 o14.5 -115 + N/A o15.5 -115 + N/A o14.5 +114 + N/A N/A N/A o57.5 -110  
Virginia Cavaliers 118 Virginia
u57.5 -110 u14.5 -115 + N/A u15.5 -115 + N/A u14.5 -145 + N/A N/A N/A u57.5 -110  
Duke Blue Devils 117 Duke
+110 even + N/A +110 + N/A +104 + N/A N/A N/A +140  
Virginia Cavaliers 118 Virginia
-130 -130 + N/A -140 + N/A -132 + N/A N/A N/A -166  

The Duke Blue Devils will take on the Virginia Cavaliers in this week's college football action. Kickoff is set for 8:00 p.m. EST at Bank of America Stadium in Charlotte, N.C. The game will be broadcast live on ABC. Here's everything you need to know about Duke vs. Virginia odds, the latest college football spreads, college football over/unders and more.

The Virginia Cavaliers opened as a -3.5 point favorite over Duke. The total is set at over/under 57.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 12/2/25

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ACC Championship Prediction

Somehow, the 7-5 Duke Blue Devils have found themselves in the ACC Championship game. When these teams met earlier in the season, the Cavaliers beat Duke 34-17. Coming into this matchup, Duke ranks 19th in EPA/pass attempt and 23rd in overall offensive success rate.

Virginia is average at best on offense, ranking 88th in passing offense and 66th in rushing offense. Duke has the offensive advantage, and Virginia has the defensive advantage. In this even of a matchup, I am going to take the team that is getting the points.

Duke vs. Virginia Prediction: Duke Blue Devils +3.5 (-110)

(Pick from Dylan Wilkerson)

Looking for more college football predictions? Check out our free college football picks and our premium subscription for the best picks!

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What Time is the ACC Championship Game?

The Blue Devils will take on the Cavaliers at 8:00 PM ET on Saturday, December 6th.

Where is the ACC Championship Game Being Played?

This game is going to be played at Bank of America Stadium in Charlotte, NC.

How Can I Watch The ACC Championship Game?

You can watch The ACC Championship on ABC.

Can Duke Beat Virginia?

Absolutely! Duke is an underdog in this game, but anything can happen in college football!

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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