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Featured Last Updated Oct 24 2025, 9:19 AM

Ole Miss vs. Oklahoma: Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
Ole Miss vs. Oklahoma: Prediction, Odds, Best Bet

Image Credit: Sarah Phipps via Imagn Images

MISS @ OU Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Ole Miss Rebels 149 Ole Miss
+2.5 -110 +3 -110 + +3 -110 + +3.5 -122 + +3 -110 + +2.5 even + +2.5 -100 + +3.5 -125 + +2.5 +105 +3.5 -130 + +5.5 -112  
Oklahoma Sooners 150 Oklahoma
-2.5 -110 -3 -110 + -3 -110 + -3.5 +102 + -3 -110 + -2.5 -130 + -2.5 -122 + -3.5 even + -2.5 -125 -3.5 -103 + -5.5 -108  
Ole Miss Rebels 149 Ole Miss
o50.5 -110 o25.5 -110 + N/A o25.5 -112 + o25.5 -110 + N/A o26.5 -115 + o25.5 -115 + o26.5 -110 o25.5 -108 + o52.5 -110  
Oklahoma Sooners 150 Oklahoma
u50.5 -110 u25.5 -110 + N/A u25.5 -108 + u25.5 -110 + N/A u26.5 -105 + u25.5 -110 + u26.5 -110 u25.5 -118 + u52.5 -110  
Ole Miss Rebels 149 Ole Miss
+150 +150 + +135 + +150 + +150 + +130 + +148 + N/A N/A +150 + +170  
Oklahoma Sooners 150 Oklahoma
-180 -180 + -160 + -180 + -178 + -170 + -184 + N/A N/A -195 + -205  
Ole Miss Rebels 149 Ole Miss
+2.5 -110 +1.5 -120 + +0.5 -110 + +1.5 -115 + +1.5 -115 + +0.5 -125 + +1.5 -128 + +0.5 -120 + +0.5 -120 +1.5 -118 + +5.5 -112  
Oklahoma Sooners 150 Oklahoma
-2.5 -110 -1.5 -110 + -0.5 -118 + -1.5 -115 + -1.5 -115 + -0.5 -105 + -1.5 +102 + -0.5 -105 + -0.5 -110 -1.5 -107 + -5.5 -108  
Ole Miss Rebels 149 Ole Miss
o50.5 -110 o10.5 -110 + N/A o10.5 -115 + o10.5 -115 + o10.5 even + o10.5 +106 + o10.5 even + o11.5 -115 o10.5 -109 + o52.5 -110  
Oklahoma Sooners 150 Oklahoma
u50.5 -110 u10.5 -120 + N/A u10.5 -115 + u10.5 -115 + u10.5 -130 + u10.5 -132 + u10.5 -125 + u11.5 -115 u10.5 -120 + u52.5 -110  
Ole Miss Rebels 149 Ole Miss
+150 +135 + +125 + +135 + +130 + +125 + +128 + N/A N/A +135 + +170  
Oklahoma Sooners 150 Oklahoma
-180 -165 + -165 + -175 + -160 + -160 + -164 + N/A N/A -175 + -205  
Ole Miss Rebels 149 Ole Miss
+2.5 -110 N/A N/A +2.5 -115 + +2.5 -110 + N/A N/A N/A N/A N/A +5.5 -112  
Oklahoma Sooners 150 Oklahoma
-2.5 -110 N/A N/A -2.5 -105 + -2.5 -110 + N/A N/A N/A N/A N/A -5.5 -108  
Ole Miss Rebels 149 Ole Miss
o50.5 -110 N/A N/A o26.5 -112 + o26.5 -115 + N/A N/A o26.5 -120 + N/A N/A o52.5 -110  
Oklahoma Sooners 150 Oklahoma
u50.5 -110 N/A N/A u26.5 -108 + u26.5 -105 + N/A N/A u26.5 -105 + N/A N/A u52.5 -110  
Ole Miss Rebels 149 Ole Miss
+150 N/A N/A +130 + N/A N/A N/A N/A N/A N/A +170  
Oklahoma Sooners 150 Oklahoma
-180 N/A N/A -155 + N/A N/A N/A N/A N/A N/A -205  
Ole Miss Rebels 149 Ole Miss
+2.5 -110 N/A N/A +0.5 -125 + N/A N/A +1.5 -120 + N/A N/A N/A +5.5 -112  
Oklahoma Sooners 150 Oklahoma
-2.5 -110 N/A N/A -0.5 -105 + N/A N/A -1.5 -110 + N/A N/A N/A -5.5 -108  
Ole Miss Rebels 149 Ole Miss
o50.5 -110 o14 -110 + N/A o13.5 -130 + N/A N/A o15.5 -108 + N/A N/A N/A o52.5 -110  
Oklahoma Sooners 150 Oklahoma
u50.5 -110 u14 -110 + N/A u13.5 even + N/A N/A u15.5 -116 + N/A N/A N/A u52.5 -110  
Ole Miss Rebels 149 Ole Miss
+150 +135 + N/A +110 + N/A N/A +118 + N/A N/A N/A +170  
Oklahoma Sooners 150 Oklahoma
-180 -160 + N/A -140 + N/A N/A -150 + N/A N/A N/A -205  
Ole Miss Rebels 149 Ole Miss
+2.5 -110 N/A N/A +0.5 -130 + N/A N/A +1.5 -130 + N/A N/A N/A +5.5 -112  
Oklahoma Sooners 150 Oklahoma
-2.5 -110 N/A N/A -0.5 even + N/A N/A -1.5 -102 + N/A N/A N/A -5.5 -108  
Ole Miss Rebels 149 Ole Miss
o50.5 -110 o13.5 -110 + N/A o10.5 -115 + N/A N/A o10.5 -110 + N/A N/A N/A o52.5 -110  
Oklahoma Sooners 150 Oklahoma
u50.5 -110 u13.5 -110 + N/A u10.5 -115 + N/A N/A u10.5 -114 + N/A N/A N/A u52.5 -110  
Ole Miss Rebels 149 Ole Miss
+150 +120 + N/A +120 + N/A N/A +132 + N/A N/A N/A +170  
Oklahoma Sooners 150 Oklahoma
-180 -140 + N/A -154 + N/A N/A -170 + N/A N/A N/A -205  
Ole Miss Rebels 149 Ole Miss
+2.5 -110 +0.5 -135 + N/A +0.5 -125 + N/A N/A +1.5 -138 + N/A N/A N/A +5.5 -112  
Oklahoma Sooners 150 Oklahoma
-2.5 -110 -0.5 +115 + N/A -0.5 -105 + N/A N/A -1.5 +104 + N/A N/A N/A -5.5 -108  
Ole Miss Rebels 149 Ole Miss
o50.5 -110 o14.5 -110 + N/A o14.5 +105 + N/A N/A o13.5 -124 + N/A N/A N/A o52.5 -110  
Oklahoma Sooners 150 Oklahoma
u50.5 -110 u14.5 -110 + N/A u14.5 -135 + N/A N/A u13.5 -100 + N/A N/A N/A u52.5 -110  
Ole Miss Rebels 149 Ole Miss
+150 +110 + N/A +110 + N/A N/A +118 + N/A N/A N/A +170  
Oklahoma Sooners 150 Oklahoma
-180 -130 + N/A -140 + N/A N/A -150 + N/A N/A N/A -205  

The Ole Miss Rebels will take on the Oklahoma Sooners in this week's NCAAF action. Kickoff is set for 12:00 p.m. EDT at Gaylord Family Oklahoma Memorial Stadium in Norman, Okla. The game will be broadcast live on ABC. Here's everything you need to know about Ole Miss vs. Oklahoma odds, the latest NFL spreads, NCAAF over/unders and more.

The Oklahoma Sooners opened as a -5.5 point favorite over Ole Miss. The total is set at over/under 54.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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Ole Miss vs. Oklahoma Best Bet

Two factors pushed me to the points: Is this the same John Mateer pre injury? He’s not using his legs nearly as much and he’s checking it down a ton.

And the second piece, how much of OU’s defense profile is based on the teams/QBs they’ve faced? Michigan? Auburn? Texas? Those are their best opponents, and all three have failed to live up to preseason hype. Gimme the points with Chambliss and the Lane Train.

Ole Miss vs. Oklahoma Best Bet: Ole Miss +5.5

(Pick from Mike Calabrese)

Looking for more best bets? Check out our free college football picks and our premium subscription for the best picks!

What Time is the Ole Miss vs. Oklahoma Game?

The Ole Miss Rebels will take on the Oklahoma Sooners at 12:00 PM EDT.

Where is the Ole Miss vs. Oklahoma Game Being Played?

This game will be played at Gaylord Family Oklahoma Memorial Stadium in Norman, OK.

How Can I Watch Ole Miss vs. Oklahoma?

You can watch Ole Miss vs. Oklahoma on ABC.

Can Ole Miss Beat Oklahoma?

Yes, with both teams coming off tough losses, you can expect each team to bring their "A" game in this big-time matchup.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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