Oregon vs. Iowa: Prediction, Odds, Best Bet

Oregon vs. Iowa: Prediction, Odds, Best Bet

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ORE @ IOWA Odds

The Oregon Ducks will take on the Iowa Hawkeyes in this week's NCAAF action. Kickoff is set for 3:30 p.m. EST at Kinnick Stadium in Iowa City, Iowa. The game will be broadcast live on CBS. Here's everything you need to know about Oregon vs. Iowa odds, the latest NCAAF spreads, NCAAF over/unders and more.

The Oregon Ducks opened as a -6.5 point favorite over Iowa. The total is set at over/under 40.5 total points scored by both teams combined.

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Updated on 11/7/25

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Oregon vs. Iowa Best Bet

This boils down to whether or not you believe Oregon is super elite (top-five). If you do hold that sentiment, you may like the Ducks here at under a touchdown, as I'm sure some do. However, I'm not in that camp and project this closer to 4.

I still maintain that the Ducks are a year away and still need to see Dante Moore prove he can get the job done on a down-to-down basis against an elite defense.

Whenever this Oregon offense has faced a defense with a pulse, it's looked rather pedestrian. Keep in mind that both of these teams hosted Indiana. Oregon was not in a position to pull off the upset, while Iowa was.

We all thought Moore had arrived in Happy Valley earlier this season, but that turned out to be more about Penn State than anything else. In fact, scoring only 17 points in regulation was kind of disappointing, looking back at it.

Now, he'll go up against a top-five defense that won't allow any explosives and sits top-two in that department almost every season. That will force Moore to stay patient and methodically work the ball down the field without making any key mistakes against Iowa's zone-heavy defense.

There are some other factors working in Iowa's favor, including the weather. It's going to be cold and windy with some serious potential precipitation. That certainly favors the Hawkeyes' style of play.

Under transfer quarterback Mark Gronowski, Iowa continues to improve on a weekly basis offensively, but it remains very limited through the air.

However, the Hawkeyes can certainly run the ball behind an outstanding offensive line, which is the exact route you want to take against an Oregon defense that just isn't creating many negative plays.

Lastly, Iowa will also have a major special teams edge. To nobody's surprise, Kirk Ferentz once again has the best special teams in the nation. Never sleep on the third phase in an Iowa game. It could ultimately decide this Big Ten showdown.

Oregon vs. Iowa Best Bet: Iowa +6

(Pick from Stuckey)

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What Time is the Oregon vs. Iowa Game?

The Oregon Ducks will take on the Iowa Hawkeyes at 3:30 PM EDT.

Where is the Oregon vs. Iowa Game Being Played?

This game is going to be played at Kinnick Stadium in Iowa City, IA.

How Can I Watch Oregon vs. Iowa?

You can watch Oregon vs. Iowa on CBS.

Can Iowa Beat Oregon?

Iowa was close to pulling off an upset in Iowa City a few weeks back against the Indiana Hoosiers - they will look to finish off the job versus Oregon this Saturday.