Last Updated Mar 02, 2022, 7:34 PM

New York Knicks vs. Philadelphia 76ers Predictions, Picks, Odds

Nationally televised NBA coverage will resume with James Harden set to make his home debut with Philadelphia, as the New York Knicks will visit the Philadelphia 76ers on Wednesday night. Coverage begins from Wells Fargo Center at 7:30 p.m. ET on ESPN.

Score Prediction

Sixers 121, Knicks 107

Best Bets

Sixers -10.5 (-110) at BetMGM

Knicks vs. Sixers Predictions

After finishing fourth in the East with a record of 41-31 SU last year, New York briefly kept that same ball rolling with another strong start to this season, as the Knicks opened with a sturdy 11-9 SU and 9-11 ATS run– which included tough victories over the Sixers (2), Bucks, Hawks, Bulls, and Lakers.

The Knicks have looked like a shell of that squad since mid-November though, considering New York enters Sunday’s matchup riding a rocky 14-27 SU skid – despite getting tagged as favorites in 18 of those contests.

On the other hand, Philadelphia posted a surprisingly mediocre start to the season, as the Sixers kicked things off with a lackluster 16-16 SU and 13-18-1 ATS stretch – while scoring just 105.4 OPPG across that timeframe.

The Sixers have dominated since the back-half of December though, considering Philadelphia enters Wednesday riding an impressive 21-7 SU and 17-11 ATS stretch – while scoring 111.7 OPPG and allowing just 105.2 DPPG across that span.

I’ll back Philadelphia here, as the Knicks enter Wednesday riding a miserable 3-15 SU skid, while scoring just 106.1 OPPG across that window, which includes an ugly loss to the Sixers on Sunday afternoon (125-109) – setting the stage for a highly unfavorable road matchup against a Sixers squad that’s 2-0 ATS and averaging 129 OPPG since the addition of Harden.

Knicks vs. Sixers Betting Odds

More Odds | Futures Odds

Knicks vs. Sixers Betting Resources

  • Matchup: Atlantic
  • Date: Wednesday, March 2, 2022
  • Venue: Wells Fargo Center
  • Location: Philadelphia, PA
  • TV-Time: ESPN - 7:30 p.m. ET
  • Injury Report

New York Knicks Betting Analysis

  • SU: 25-36
  • ATS: 26-35
  • O/U: 30-31

New York seemingly caught the entire conference by surprise last season, as the Knicks finished fourth in the East with a sturdy record of 41-31 SU – before inevitably getting bounced by the Hawks in a quick five-game set to open the playoffs.

The Knicks haven’t caught anybody off guard this season though, considering New York ranks 12th in the East straight-up with a record of 25-36 SU, and 13th against the spread with a record of 26-35 ATS – despite getting tagged as favorites in 32 matchups so far this season.

Philadelphia 76ers Betting Analysis

  • SU: 37-23
  • ATS: 30-29-1
  • O/U: 26-32-2

After earning the top spot in the East with a record of 49-23 SU last year, the Sixers stumbled out to a surprisingly slow start to this season, as Philadelphia went just 16-16 SU across their opening 32-game stretch – while averaging less than 106 OPPG during that timeframe (105.4 OPPG).

Joel Embiid has single-handedly carried the Sixers through most of the new year, considering Philadelphia enters Wednesday riding a sturdy 21-7 SU run, propelled by Embiid averaging 33.6 PPG, 11.3 REB, 4.5 AST, and 1.4 BLK across that window.

Fortunately, help has arrived in the form of Harden, as Philadelphia acquired the ten-time All-Star at the trade deadline, and he’s made an immediate impact, highlighted by the Beard averaging 28 PPG and 14 AST across his first two performances with the Sixers.

The Sixers are 16-2 SU in their last 18 matchups against New York. (AP)

Knicks vs. Sixers Head-to-Head

The Sixers swept a three-game regular-season set against New York last year, with all three matchups staying under the total at an average of 198 PPG. The Knicks flipped it around and went 2-0 SU against Philadelphia to start this season though, with both contests also staying under the number at an average of 205 PPG. But the most recent matchup between these teams took place just a few days ago, which resulted in a relatively high-scoring victory for the Sixers (125-109).

Key Players to Watch

  • NYK: Julius Randle - PF (19.6 PPG, 10.2 REB, 5.3 AST)
  • NYK: RJ Barrett - SG (18.7 PPG, 5.7 REB, 2.7 AST)
  • PHI: Joel Embiid - C (29.8 PPG, 11.1 REB, 4.4 AST)
  • PHI: James Harden - PG (22.7 PPG, 8 REB, 10.3 AST)

Knicks vs. Sixers Betting Conclusion

After stomping New York at MSG on Sunday afternoon (W, 125-109), the Sixers return home for Wednesday’s contest as ten-point favorites over the Knicks at Wells Fargo Center – marking the 11th time New York has been an underdog across their last 15 games.

I’ll back Philadelphia here, as the Sixers sit 2-0 SU and ATS since Harden’s debut, with both victories coming by 16+ PTS – likely presenting a steep uphill battle for a Knicks squad that’s averaging just 106.1 OPPG across their latest 3-15 SU skid.

Knicks vs. Sixers Betting Trends

  • The Knicks are 0-5 ATS in their last five games.
  • The Sixers are 16-2 SU in their last 18 matchups against New York.
  • The total has gone OVER in six of the last seven Knicks' games.
  • Thre total has gone UNDER in five of the last six matchups between the Sixers and Knicks.
  • The total has gone OVER in four of the last five Sixers' games.
  • The Sixers are 4-1 ATS in their last five games.
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