Lions vs. Panthers Predictions: Sunday Night Football Brings Points
Dylan Wilkerson Sports Betting Expert
The Detroit Lions will take on the Carolina Panthers in this week's NFL action. Kickoff is set for 8:20 PM EST at Bank of America Stadium in Charlotte, NC. The game will be broadcast live on NBC. Here's everything you need to know about Lions vs. Panthers odds, the latest college football spreads, college football over/unders and more.
DET @ CAR Odds
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open |  › |  › |  › |  › |  › |  › |  › |  › |  | ||
 277 Lions | -3 -110 | -3.5 -115 | -3.5 -110 | -3.5 -112 | -3.5 -112 | -3.5 -118 | -4 -110 | -3.5 -110 | -4 -107 | -3.5 -112 | |
 278 Panthers | +3 -110 | +3.5 -105 | +3.5 -108 | +3.5 -108 | +3.5 -108 | +3.5 -104 | +4 -110 | +3.5 -110 | +4 -114 | +3.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | o47.5 -110 | o50.5 -115 | o51 -108 | o50.5 -122 | o50.5 -117 | o50.5 -115 | o51 -110 | o51 -110 | o51 -110 | o50.5 -122 | |
| 278 Panthers | u47.5 -110 | u50.5 -105 | u51 -110 | u50.5 +102 | u50.5 -104 | u50.5 -105 | u51 -110 | u51 -110 | u51 -108 | u50.5 +102 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -155 | -200 | -200 | -185 | -197 | -200 | -200 | -195 | -190 | -185 | |
| 278 Panthers | +130 | +165 | +165 | +154 | +164 | +168 | +165 | +160 | +155 | +154 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -3 -110 | -2.5 -120 | -2.5 -120 | -2.5 -120 | -2.5 -118 | -2.5 -120 | -2.5 -125 | -2.5 -120 | -2.5 -120 | -3.5 -112 | |
| 278 Panthers | +3 -110 | +2.5 even | +2.5 even | +2.5 even | +2.5 -102 | +2.5 -100 | +2.5 -105 | +2.5 even | +2.5 -106 | +3.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | o47.5 -110 | o24.5 -115 | o24.5 -110 | o25.5 -108 | o24.5 -124 | o25.5 -110 | o25.5 -115 | o24.5 -115 | o25.5 -112 | o50.5 -122 | |
| 278 Panthers | u47.5 -110 | u24.5 -105 | u24.5 -108 | u25.5 -112 | u24.5 +103 | u25.5 -110 | u25.5 -115 | u24.5 -115 | u25.5 -112 | u50.5 +102 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -155 | -170 | -175 | -175 | -170 | -178 | N/A | -175 | -159 | -185 | |
| 278 Panthers | +130 | +145 | +145 | +145 | +138 | +146 | N/A | +145 | +130 | +154 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -3 -110 | -0.5 +105 | -0.5 +105 | -0.5 +110 | N/A | -1.5 +112 | -0.5 +105 | -0.5 +110 | -1.5 +112 | -3.5 -112 | |
| 278 Panthers | +3 -110 | +0.5 -125 | +0.5 -135 | +0.5 -130 | N/A | +1.5 -136 | +0.5 -130 | +0.5 -135 | +1.5 -139 | +3.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | o47.5 -110 | o9.5 -135 | o9.5 -145 | o9.5 -135 | N/A | o9.5 -140 | o9.5 -140 | o9.5 -150 | o9.5 -148 | o50.5 -122 | |
| 278 Panthers | u47.5 -110 | u9.5 +115 | u9.5 +115 | u9.5 +114 | N/A | u9.5 +116 | u9.5 +110 | u9.5 +110 | u9.5 +117 | u50.5 +102 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -155 | -150 | -150 | -148 | N/A | -160 | N/A | -160 | -139 | -185 | |
| 278 Panthers | +130 | +125 | +120 | +124 | N/A | +130 | N/A | +120 | +114 | +154 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -3 -110 | -1.5 -110 | N/A | -1.5 -115 | N/A | -1.5 -110 | -1.5 -115 | N/A | -1.5 -115 | -3.5 -112 | |
| 278 Panthers | +3 -110 | +1.5 -110 | N/A | +1.5 -115 | N/A | +1.5 -110 | +1.5 -115 | N/A | +1.5 -108 | +3.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | o47.5 -110 | o24.5 -110 | N/A | o25.5 -115 | N/A | o24.5 -110 | o24.5 -115 | N/A | o24.5 -106 | o50.5 -122 | |
| 278 Panthers | u47.5 -110 | u24.5 -110 | N/A | u25.5 -105 | N/A | u24.5 -110 | u24.5 -115 | N/A | u24.5 -115 | u50.5 +102 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -155 | -150 | N/A | -154 | N/A | -148 | N/A | N/A | -152 | -185 | |
| 278 Panthers | +130 | +125 | N/A | +120 | N/A | +126 | N/A | N/A | +123 | +154 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -3 -110 | N/A | N/A | -1.5 -115 | N/A | -1.5 -108 | -1.5 -115 | N/A | N/A | -3.5 -112 | |
| 278 Panthers | +3 -110 | N/A | N/A | +1.5 -115 | N/A | +1.5 -114 | +1.5 -120 | N/A | N/A | +3.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | o47.5 -110 | o14.5 -115 | N/A | o14.5 -115 | N/A | o15.5 -110 | o15.5 -120 | N/A | N/A | o50.5 -122 | |
| 278 Panthers | u47.5 -110 | u14.5 -115 | N/A | u14.5 -115 | N/A | u15.5 -110 | u15.5 -110 | N/A | N/A | u50.5 +102 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -155 | -155 | N/A | -166 | N/A | -162 | N/A | N/A | N/A | -185 | |
| 278 Panthers | +130 | +122 | N/A | +130 | N/A | +132 | N/A | N/A | N/A | +154 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -3 -110 | N/A | N/A | -0.5 +105 | N/A | -1.5 +122 | -0.5 +105 | N/A | N/A | -3.5 -112 | |
| 278 Panthers | +3 -110 | N/A | N/A | +0.5 -135 | N/A | +1.5 -148 | +0.5 -135 | N/A | N/A | +3.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | o47.5 -110 | o9.5 -140 | N/A | o10.5 +110 | N/A | o9.5 -144 | o9.5 -155 | N/A | N/A | o50.5 -122 | |
| 278 Panthers | u47.5 -110 | u9.5 +110 | N/A | u10.5 -140 | N/A | u9.5 +118 | u9.5 +120 | N/A | N/A | u50.5 +102 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -155 | -145 | N/A | -140 | N/A | -142 | N/A | N/A | N/A | -185 | |
| 278 Panthers | +130 | +115 | N/A | +110 | N/A | +116 | N/A | N/A | N/A | +154 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -3 -110 | -0.5 -105 | N/A | -0.5 -115 | N/A | -1.5 +114 | -0.5 -110 | N/A | N/A | -3.5 -112 | |
| 278 Panthers | +3 -110 | +0.5 -125 | N/A | +0.5 -115 | N/A | +1.5 -138 | +0.5 -120 | N/A | N/A | +3.5 -108 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | o47.5 -110 | o13.5 -130 | N/A | o14.5 -110 | N/A | o13.5 -128 | o14.5 even | N/A | N/A | o50.5 -122 | |
| 278 Panthers | u47.5 -110 | u13.5 even | N/A | u14.5 -120 | N/A | u13.5 +104 | u14.5 -140 | N/A | N/A | u50.5 +102 | |
| Open | › | › | › | › | › | › | › | › | | ||
| 277 Lions | -155 | -135 | N/A | -140 | N/A | -140 | N/A | N/A | N/A | -185 | |
| 278 Panthers | +130 | +105 | N/A | +110 | N/A | +112 | N/A | N/A | N/A | +154 | |
The Detroit Lions opened as a -3.5 point favorite to Carolina. The total is set at over/under 50.5 total points scored by both teams combined.
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Updated on 10/1/26
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Lions vs. Panthers Prediction
Detroit's offense needs no introduction. They've scored exactly 31 points in all 3 games to begin the season. Detroit will face a Carolina defense likely missing both starting corners.
Carolina's offense has been a pleasant surprise. The new coaching staff has revamped the passing game. Bryce Young leads the league in yards through 3 games. Carolina ranks 2nd in neutral pass rate and 2nd in pace. Detroit's scuffling defense ranks 31st in EPA/play.
Updated on 10/1/26
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Lions vs. Panthers Prediction: Detroit Lions @ Carolina Panthers o50.5 (-115)
(Pick from Charlie Wright)
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