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Cardinals @ 49ers

Arizona Cardinals
Arizona Cardinals
o43.5
o43.5 / -1.5
NFL -
San Francisco 49ers
San Francisco 49ers
-1.5

Cardinals injuries

Pos Player Status
OL Will Hernandez (Knee) Out
DE Dante Stills (Heel) Questionable
LB Owen Pappoe (Quad) Questionable

49ers injuries

Pos Player Status
QB Brock Purdy (Toe) Out
QB Brock Purdy (Toe) Doubtful
WR Jauan Jennings (Shoulder) Questionable
TE George Kittle (Hamstring) Out
QB Brock Purdy (Toe) Questionable
RB Christian McCaffrey (Calf) Questionable
RB Jordan James (Finger) Doubtful
WR Jordan Watkins (Ankle) Doubtful
WR Jacob Cowing (Hamstring) Out
WR Demarcus Robinson (Suspension) Out
WR Brandon Aiyuk (Knee) Out
WR Jauan Jennings (Calf) Questionable

ARI @ SF Line Movements

Spread

Open: SF -3.5
-1.5 -1.9 -2.3 -2.7 -3.1 -3.5
  • 5/15 02:41am
  • SF -3.5
  • 9/09 07:30pm
  • SF -2.5
  • 9/11 03:44pm
  • SF -1.5
Best Home Odds
-1.5 even
+
Best Away Odds
+1.5 -110
+

Total

Open: o47.5
42.5 43.5 44.5 45.5 46.5 47.5
  • 5/15 02:41am
  • o47.5
  • 9/09 07:30pm
  • o44.5
  • 9/11 03:44pm
  • o43.5
  • 9/11 03:45pm
  • o42.5
  • 9/14 10:38pm
  • o43.5
Best Over
o43.5 -110
+
Best Under
u43.5 -105
+

Moneyline

Open: ARI +150 SF -180
-198 -125.6 -53.2 +19.2 +91.6 +164
  • 5/15 02:41am
  • SF -180
  • 5/28 08:52pm
  • SF -175
  • 5/29 10:02pm
  • SF -180
  • 5/30 08:18pm
  • SF -175
  • 7/01 10:07pm
  • SF -185
  • 7/11 08:11am
  • SF -192
  • 7/18 08:41pm
  • SF -198
  • 7/18 08:47pm
  • SF -192
  • 7/18 10:38pm
  • SF -198
  • 7/19 09:02pm
  • SF -192
  • 5/15 02:41am
  • ARI +150
  • 5/28 08:52pm
  • ARI +145
  • 5/29 10:02pm
  • ARI +150
  • 5/30 08:18pm
  • ARI +145
  • 7/01 10:07pm
  • ARI +154
  • 7/11 08:11am
  • ARI +160
  • 7/18 08:41pm
  • ARI +164
  • 7/18 08:47pm
  • ARI +160
  • 7/18 10:38pm
  • ARI +164
  • 7/19 09:02pm
  • ARI +160
Best Home Odds
-118
+
Best Away Odds
+105
+

Saints vs. 49ers Head-to-Head

Date Team Opp Close Result ATS/OU
Sep 14, 2025 49ers @Saints -3 / 40.5 Won 26-21 Won / Over
Aug 18, 2024 49ers Saints +1 / 37.5 Won 16-10 Won / Under
Nov 27, 2022 49ers Saints -8.5 / 43.5 Won 13-0 Won / Under
Nov 15, 2020 49ers @Saints +9.5 / 49.5 Lost 13-27 Lost / Under
Dec 8, 2019 49ers @Saints +1 / 45 Won 48-46 Won / Over
Nov 6, 2016 49ers @Saints -5 / 53 Lost 0-0 Lost / Under
Nov 9, 2014 49ers Saints -6 / 49.5 Lost 0-0 Lost / Under
Nov 17, 2013 49ers Saints -3.5 / 50 Lost 0-0 Lost / Under
Nov 25, 2012 49ers Saints +1 / 50 Lost 0-0 Won / Under
Jan 14, 2012 49ers @Saints -3.5 / 46.5 Lost 0-0 Lost / Under

Cardinals vs 49ers Odds

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