NFL Odds Week 7: Browns vs Colts Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

5 minute read

Week 7 of the NFL season continues with the Browns looking to capitalize off their home upset of the 49ers as Cleveland heads to Indianapolis. The odds favor the Browns by 2.5 points as they seek consecutive wins for the first time this season. Catch all the action live from Lucas Oil Stadium on Sunday, October 22 at 1:00 p.m. ET on CBS.

Here's everything you need to know about the NFL odds for Week 7 Browns vs Colts: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

Cleveland Browns vs Indianapolis Colts Odds

• Opening point spread: Browns -1
• Opening moneyline: Browns -130/Colts +110
• Opening total: Over/Under 39.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

UPDATE 10 A.M. ET SUNDAY: BetMGM is up a half-point since Friday (see below update), with the Browns now at -3.5. Ticket count is just shy of 3/1 and money 2.5/1 on Cleveland.

The total is at 40.5, as it was Friday, after spending much of the past 24 hours at 41. Ticket count is 5/1-plus and money 9/1 on the Under at BetMGM.

UPDATE 1:30 P.M. ET FRIDAY: Cleveland has been a short chalk all week at BetMGM, but the number has bounced around a bunch. The Browns opened -1.5 (Over -115), peaked at -3 Wednesday and again Thursday, then backed up to -1.5 briefly late this morning.

Cleveland has since rebounded to -3 (-115), with Deshaun Watson (shoulder) looking likely to be back under center this week. Spread ticket count is almost 5/1 and spread money beyond 6/1 on the Browns. Cleveland has the third-most spread tickets and third-most spread money at BetMGM this week.

There's been back-and-forth with the total, as well. BetMGM opened at 39.5 and got to 41.5 Wednesday before quickly falling back to 40. The number touched 41.5 again Thursday and is now at 40.5.

Tickets and money are in the 8/1 range on the Under. In fact, by ticket count at BetMGM, Browns-Colts is the most-bet Under in the NFL Week 7 odds market.

Further, every single Week 7 total has a majority of tickets on the Under, and only two games have a majority of money on the Over: Steelers-Rams (58%) and Cardinals-Seahawks (52%). The public seems to be riding last week's 12-2-1 Under run in the NFL.

UPDATE 11 P.M. ET SUNDAY: With unheralded PJ Walker at quarterback, Cleveland pulled the upset against previously unbeaten – and Super Bowl favorite – San Francisco. The Browns (3-2 SU and ATS) got two late fields goal to take the lead, and the Niners missed a final-seconds field goal, giving Cleveland a 19-17 victory catching 9.5 points at home.

Indianapolis (3-3 SU and ATS) saw sharp play in Week 6, but had no answer for Jacksonville. The Colts closed as 4-point 'dogs and fell behind 31-6 en route to a 37-20 loss.

Michaelson said the risk room struggled a bit with the Browns-Colts matchup in the NFL odds Week 7 market. The Browns might again have Walker at QB, while Gardner Minshew will remain in for the Colts, with rookie Anthony Richardson (rotator cuff) on IR.

"Making this line was like a jigsaw puzzle. Both teams will [likely] be using backup quarterbacks, and they're coming off very different results," Michaelson said. "Indianapolis looked outclassed by Jacksonville, while Cleveland had a huge win against San Fran. I expect this line to jump around a lot, as different groups will have different valuations of factors such as Walker, Minshew and if this is a classic letdown spot for Cleveland.

"There was certainly disagreement in the risk room in making this line in the first place."

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 7 Report containing spreads, lines, and trends for every NFL matchup.

Browns vs Colts Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

Both defenses have the advantage here. Indianapolis isn't about to hang a huge number on this Browns defense the way it's dominating, but the Colts defense can hang too. Gus Bradley's unit has been stout, and don't let last week's 37 points allowed to the Jaguars throw you off. The defense was actually pretty good, just killed by constant Minshew turnovers.

Browns games are averaging 34.4 PPG, and that number would be lower if not for the one Cleveland over when there were two defensive TDs. Kevin Stefanski games with a total below 44 are 13-6 to the under (68%), and games featuring home underdogs have gone under 61% of the time the last two years.

This was my Hot Read, and though the line initially dipped from 42.5 to 39.5, it's rebounded back a bit and I still see value. This was an under all the way for me. Just grab the best number you can find.

Pick: Under 40.5 (-110)

For more NFL picks, check out Action Network's NFL Week 7: How to Bet Every Game & Every Team.

The One Stat to Know About Browns vs Colts

Action Network NFL researcher Evan Abrams offers his top betting stat:

Anthony Richardson is most likely done for the season. Which means in Indy it's Minshew Time. Minshew is 2-6 SU in “toss up” games. Spread of 3 or less and 3-9 SU in games with spread of 4 or less.

For more NFL betting stats, check out Action Network's NFL Week 7 Betting Trends, Stats, Notes. Plus, you can use our ESPN Bet promo code for up to $1000 in bonus offers!

Where to place a bet this NFL Season?

• Use our exclusive BetMGM Bonus Code VIBONUS1500 to unlock BetMGM’s welcome offer for new sportsbook users!
• Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
• Check out the North Carolina Sportsbooks just before they launch legal online sports betting.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson