Rams vs. Broncos Prediction: Ferguson Has A Big Day

Rams vs. Broncos Prediction: Ferguson Has A Big Day

Updated on 9/25/26

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The Los Angeles Rams will take on the Denver Broncos in this week's NFL action. Kickoff is set for 8:20 p.m. EST at Empower Stadium in Denver, CO. The game will be broadcast live on NBC. Here's everything you need to know about Rams vs. Broncos odds, the latest college football spreads, college football over/unders and more.

LA @ DEN Odds

The Los Angeles Rams opened as a -2.5 point favorite to Denver. The total is set at over/under 45.5 total points scored by both teams combined.

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Updated on 9/25/26

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Rams vs. Broncos Prediction

With Ferguson's role expanding with Puka Nacua possibly out, I am making a bigger bet than usual and betting to win 2 units.

Davante Adams had a huge game last week with Nacua out, and he might do it again this week with Nacua trending towards not playing. Adams' matchup against CB Patrick Surtain, however, is one of the toughest individual matchups in the league. Those two should be locked in together nearly all game, possibly limiting another huge game from Adams, as Surtain is one of the best CBs in the league.

That leaves Ferguson likely to see huge volume as a primary slot WR and inline TE. Parker Washington had a huge game last week against the Broncos as the Jaguars' primary slot WR, and Travis Kelce had 71 yards against them in Week 1.

With Nacua out last week, Ferguson had 9 targets and hauled in 6 of them for 54 yards, and that looks very likely to happen again this week.

bet ferguson over receiving yards now

Rams vs. Broncos Prediction: Terrance Ferguson o41.5 Receiving Yards (-115)

(Pick from Dylan Wilkerson)

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