2026 College Football Odds Week 11: Lines, Spreads, Betting Trends on Biggest Games

2026 College Football Odds Week 11: Lines, Spreads, Betting Trends on Biggest Games

College Football Week 11 Odds include key matchups involving multiple teams in the College Football Playoff chase.

Missouri vs. Georgia and USC vs. Indiana loom large in Week 11 college football odds, as does Texas vs. LSU. But don't overlook Illinois vs. UCLA and Utah vs. Arizona, with the Bruins and Utes the last of the unbeatens.

Here’s everything you need to know about 2026 college football odds Week 11: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on college football Week 11 odds and action.

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Updated on 11/8/26

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2026 College Football Odds for Week 11

Illinois vs. UCLA Odds

ILL @ UCLA Odds

  • Opening point spread: UCLA -8.5
  • Opening moneyline: UCLA TBA/Illinois TBA
  • Opening total: Over/Under 45.5 points scored
  • Time: 9 p.m. ET Friday (FOX)

OPENING ODDS UPDATE: UCLA is spotless on the field and at the betting window, at 9-0 SU and ATS, the best spread-covering mark in the nation. In Week 10, the Bruins pulled away in the fourth quarter for a 34-20 win laying 3.5 points at Minnesota.

UCLA was No. 8 in the first CFP rankings of the year, released last week. The next rankings come out Tuesday.

Illinois (6-3 SU/4-4-1 ATS) is on a four-game winning streak, including a 21-10 Week 8 upset of Oregon as a 10.5-point home underdog. In Week 10, the Fighting Illini were 4.5-point home pups vs. Nebraska and won 24-13, cashing for the third straight game.

Circa Sports' college football openers are well-respected and often get early action. On Sunday afternoon, Circa opened UCLA -8.5 in college football Week 11 odds. Less than 30 minutes later, the Bruins went straight to -10.

Circa's total saw some early activity, as well, going from 45.5 straight to 47.5 after about 25 minutes, then settling at 46.5 a few minutes later.

Duke vs. Miami Odds

  • Opening point spread: Miami -13.5
  • Opening moneyline: Miami TBA/Duke TBA
  • Opening total: Over/Under 54.5 points scored
  • Time: Noon ET Saturday (ABC)

OPENING ODDS UPDATE: Miami (8-1 SU/6-3 ATS) was minus star wideout Malachi Toney vs. Notre Dame and fell into a 24-3 hole by early in the third quarter. The Hurricanes made a huge comeback and nearly forced overtime, but fell short 31-24 catching 7.5 points on the road.

Duke (7-2 SU and ATS) rebounded from back-to-back losses by winning and cashing in its last three games. In Week 10 at North Carolina State, the Blue Devils rumbled to a 41-3 victory as 4.5-point favorites.

That was on the heels of a 47-2 rout of Boston College as a 6.5-point home favorite. So that's two wins by a combined 88-5.

Still, Miami opened -13.5 in Circa Sports' college football odds Week 11. There was no movement in the first hour Sunday.

USC vs. Indiana Odds

  • Opening point spread: Indiana -7
  • Opening moneyline: Indiana TBA/USC TBA
  • Opening total: Over/Under 49.5 points scored
  • Time: 3:30 p.m. ET Saturday (CBS)

OPENING ODDS UPDATE: Indiana is 8-1 SU, right in the CFP mix at No. 4 in the first rankings of the year. But the Hoosiers are tied for the worst spread-covering mark in the nation at 1-8 ATS.

Indiana is coming off a bye, after barely escaping Week 9 with a 23-16 overtime victory vs. Minnesota. That was miles short of covering the number, with the Hoosiers 20.5-point home favorites.

USC (7-2 SU/3-6 ATS) is also coming off a bye, after saving its CFP hopes with a big upset in Week 9. The Trojans were 6.5-point home underdogs vs. Ohio State and never trailed in a 30-18 victory.

Circa opened USC-Indiana at Hoosiers -7 in Week 11 college football odds. Within 10 minutes, Indiana moved off the key number to -7.5.

Missouri vs. Georgia Odds

Missouri @ Georgia Betting Odds

  • Opening point spread: Georgia -14.5
  • Opening moneyline: Georgia TBA/Missouri TBA
  • Opening total: Over/Under 47 points scored
  • Time: 3:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: Georgia (8-1 SU/7-2 ATS) is likely to ascend to No. 1 when the next CFP rankings are released on Tuesday. The Bulldogs entered Week 10 at No. 2, then smoked Ole Miss 42-7 as 3.5-point road favorites.

Meanwhile, Missouri's CFP hopes are likely finished after a second loss in three weeks and a third setback of the season. The Tigers (6-3 SU/4-5 ATS) closed as 2.5-point home 'dogs vs. Texas and led 20-13 with 4:52 left in the third quarter.

But Mizzou gave up the final 21 points in a 34-20 loss.

Circa Sports opened Georgia -14.5 vs. Mizzou in college football Week 11 odds, with no movement in the first hour Sunday afternoon.

Texas vs. LSU Odds

  • Opening point spread: LSU -4.5
  • Opening moneyline: LSU TBA/Texas TBA
  • Opening total: Over/Under 46 points scored
  • Time: 7:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: Texas (7-2 SU/4-5 ATS) kept its CFP hopes afloat with a must-have road win in Week 10. The Longhorns trailed Missouri 20-13 with 4:52 left in the third quarter, but scored the final 21 points in a 34-20 victory as 2.5-point road favorites.

On the flip side, LSU (6-3 SU/4-5 ATS saw its CFP hopes almost assuredly evaporate. The Tigers were 6-point home favorites vs. Alabama and got smacked 31-13, giving up the final 21 points after taking a 13-10 lead late in the third quarter.

Despite that home loss, LSU opened -4.5 vs. Texas in Circa's college football odds Week 11. There was no movement in the first hour Sunday afternoon.

Utah vs. Arizona Odds

Utah @ Arizona Betting Odds

  • Opening point spread: Utah -3
  • Opening moneyline: Utah TBA/Arizona TBA
  • Opening total: Over/Under 53 points scored
  • Time: 7:30 p.m. ET Saturday (TV TBA)

OPENING ODDS UPDATE: Utah (9-0 SU/8-1 ATS) is nearly as impressive against the number as UCLA. In Week 10, the Utes found themselves in a back-and-forth battle vs. archrival BYU, but came out with a 28-20 victory as 4.5-point home favorites.

Arizona (7-2 SU/3-6 ATS) got a skin-of-its-teeth victory to stay in the Big 12 hunt. The Wildcats trailed TCU 28-20, but scored nine points in the final two minutes to post a 29-28 victory giving 6 points at home.

Arizona got a TD with 1:45 remaining, but the 2-point conversion attempt failed. However, the Wildcats recovered a pooch kick on the ensuing kickoff, leading to a game-winning field goal with 38 seconds remaining.

Utah opened as 3-point road chalk in Circa's Week 11 college football odds. Within a few minutes Sunday afternoon, the Utes dipped to -2.5. Eighty minutes later, Utah fell to -1.5/-1.

The total bumped from 53 to 54 after about 30 minutes.

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