New Orleans Saints vs. Seattle Seahawks Predictions, Odds, Picks

Oct. 25, 2021
Michael Crosson
VI Betting Expert
VegasInsider.com

The seventh week of regular season NFL action will conclude with prime-time NFC showdown, as the New Orleans Saints will take on the Seattle Seahawks at Lumen Field on Monday night. Coverage begins at 8:15 p.m. ET on ESPN.

Score Prediction

Saints 27, Seahawks 20

Best Bets

New Orleans -4

Jameis Winston (NOR/QB) – Over 200 Passing Yards (-115)

New Orleans Saints vs. Seattle Seahawks Predictions

Following the retirement of Drew Brees, nobody really knew what to expect from the new-look Saints’ offense heading into this season – considering New Orleans swapped out a future hall-of-fame QB in Brees to a notoriously inconsistent signal-caller in Winston.

Through Winston’s first six weeks with New Orleans though, “inconsistent” is the perfect word to describe their offensive attack, considering the Saints racked up 33 PPG across victories over the Packers, Patriots, and Washington in Weeks 1, 3, and 5 – and scored just 14 PPG across losses to the Panthers and Giants in Weeks 2 and 4.

On the other hand, the Seahawks are currently having a bit of a down-season, considering Pete Carroll’s squad stumbled out to a relatively underwhelming 2-2 start with losses to Minnesota and Tennessee – and then in Week 5, Russell Wilson injured his throwing hand, which may keep Seattle’s seven-time Pro- Bowl QB sidelined through Week 10.

Since the midway point of Week 5, former Jets’ QB Geno Smith has stepped in for Wilson, and while Seattle is still yet to entirely fall apart, it’s tough to vouch for either of Geno’s latest efforts – considering the Seahawks averaged just 18.5 PPG on 213.5 PYPG across the last two weeks.

I’ll lay the points with the Saints here, as New Orleans has racked up 28 points or more in three out of five games so far this season – and I highly doubt the Seahawks’ offense will match a similar level of offensive production with a backup QB at the helm.

New Orleans Saints vs. Seattle Seahawks Betting Odds

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The Saints will travel to Seattle on Monday night as four-to-five-point favorites over the Seahawks a Lumen Field – marking the fourth straight game Seattle has been an underdog.


The total for Monday’s event opened around OU 44 at most shops – but since then, that number has stooped down to roughly OU 42, which marks the lowest bar set for a matchup containing either of these teams this year.


New Orleans Saints vs. Seattle Seahawks Betting Resources

  • Matchup: NFC South vs. NFC West
  • Date: Monday, October 25, 2021
  • Venue: Lumen Field
  • Location: Seattle, Washington
  • TV-Time: ESPN - 8:15 p.m. ET

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New Orleans Saints Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 3-2
  • ATS: 3-2
  • O/U: 2-3
  • ATS - Home: 1-1
  • ATS - Away: 2-1

Heading into the new season, the Saints stood as somewhat of a wildcard amongst the playoff contenders in NFC, considering New Orleans retired an incredibly consistent, veteran quarterback during the offseason – and replaced him with the ultimate wildcard in Jameis.

This season though, Winston’s style of play still appears incredibly chaotic, but he’s seemingly turned it into a form of slightly controlled chaos, considering Jameis has completed just 60.3% of his passes this year – yet he also boasts a career-best a 12-3 TD-INT ratio and the second-highest QBR of his career (61.2 QBR).

Downgrading from Brees to Winston under-center makes the Saints considerably less threatening in terms of championship contention – but Jameis still appears to be settling into his new system, which should only lead to steadier offensive production from New Orleans as the season progresses.

Seattle Seahawks Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 2-4
  • ATS: 3-3
  • O/U: 1-4-1
  • ATS - Home: 0-2
  • ATS - Away: 3-1

Seattle’s opening stretch of performances wasn’t exactly encouraging, considering the Seahawks entered Week 5 boasting a pedestrian 2-2 record – with both of those losses coming in matchups they were originally favored in (TEN +6.5, MIN +2).

Following Wilson’s hand injury in Week 5 though, that pedestrian 2-2 record quickly plummeted to a disappointing 2-4 mark, as Seattle posted a pair of discouraging losses against the Rams and Steelers in their latest two affairs – highlighted by the Seahawks’ offense generating just 18.5 PPG across that window.


The point total has gone UNDER in three of the last four games played between both teams. (AP)

Inside the Stats - New Orleans Saints

  • Record: 3-2
  • Division Standing: 2nd - NFC South
  • Points Scored: 127
  • Points Allowed: 91
  • PS/G: 25.4 (9th)
  • PA/G: 18.2 (4th)

Inside the Stats - Seattle Seahawks

  • Record: 2-4
  • Division Standing: 4th - NFC West
  • Points Scored: 140
  • Points Allowed: 149
  • PS/G: 23.3 (18th)
  • PA/G: 24.8 (21st)

Key Players to Watch

  • NOR: Jameis Winston - QB (70/116, 892 yards, 12 TD)
  • NOR: Alvin Kamara - RB (94 carries, 368 yards, TD)
  • SEA: Geno Smith - QB (33/49, 340 yards, 2 TD, INT)
  • SEA: D.K. Metcalf - WR (31 catches, 44 yards, 5 TD)

New Orleans Saints vs. Seattle Seahawks Betting Conclusion

After racking up 33 points on 369 total yards against Washington in Week 5, the Saints will return from their bye-week as generous road-favorites over the Seahawks at Lumen Field in Week 7 – marking the fourth straight game Seattle has been an underdog in.

I’ll lay the points with New Orleans here, as the Seahawks generated just 18.5 PPG on 213.5 PYPG across their latest two performances – and that dismal level of offensive production shouldn’t be nearly enough to keep up with the Saints on Monday night, which is why I’m also backing Winston to make it a third straight game with 200+ passing yards in this affair.

New Orleans Saints vs. Seattle Seahawks Betting Trends

  • New Orleans has won 16 of its last 17 games when playing in October.
  • Seattle has failed to cover the spread in four of its last five games when facing the NFC.
  • New Orleans has covered the spread in three straight games.
  • The point total has gone UNDER in three of the last four meetings.

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