Houston Texans vs. Tennessee Titans Predictions, Odds, Picks

Nov. 21, 2021
Jonathan Willis
VI Betting Expert

An AFC South meeting sees the Houston Texans travel to a red hot Tennessee Titans team on Sunday afternoon. Opening kick is set for 1:00 p.m. ET and will air on CBS from Nissan Stadium in Nashville, Tennessee.

Score Prediction

Titans 23, Texans 17

Best Bets


Texans +10.5

Houston Texans vs. Tennessee Titans Predictions

Tennessee is on pace to be the No. 1 overall seed in the AFC. Despite the loss of Derrick Henry, the Titans have continued to win games, knocking off the Los Angeles Rams and New Orleans Saints since his potentially season-ending foot injury. They could be in line for a letdown against the Houston Texans this week though, as they must face the New England Patriots next Sunday in Foxboro.

The Titans are double-digit home favorites against the Texans this week. Tennessee has not been as impressive on offense since Henry was injured though, effecting the play of Ryan Tannehill. This defense is severely banged up and may be without as many as six starters on Sunday, so Houston has the potential to pull off the upset.

Houston Texans vs. Tennessee Titans Betting Odds

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Houston Texans vs. Tennessee Titans Betting Resources

  • Matchup: AFC South
  • Date: Sunday, November 21, 2021
  • Venue: Nissan Stadium
  • Location: Nashville, Tennessee
  • TV-Time: CBS - 1:00 p.m. ET

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Houston Texans Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 1-8
  • ATS: 4-5
  • O/U: 4-5
  • ATS - Home: 3-1
  • ATS - Away: 1-4

Tyrod Taylor did not play well against the Miami Dolphins in his return last week. He threw three interceptions, leading to a loss in what was a very winnable game for the Texans. Taylor looked rusty, but he should play much better this week against the Titans.

The Texans don’t have many weapons on offense. Brandin Cooks is easily the top receiver with 57 receptions for 641 yards and two touchdowns, as no other player has more than 200 receiving yards. Danny Amendola could be in line for a nice stat line this week though, as he has been targeted at least five times in each of his last three games.

Houston has been dreadful at running the ball this season. The Texans are averaging just 3.3 YPC, ranking dead last in the league. That has been a part of why they rank dead last in scoring offense (14.2 PPG) and total offense (280.1 YPG), but they could have some success running the ball against a banged-up Tennessee front seven.

This defense hasn’t been good, but the Texans are at least relatively healthy. Christian Kirksey is the only starter that will miss the game, while defensive end Jonathan Greenard is questionable. If they can bottle up the run, Houston’s front seven might be able to make this game very interesting.

Tennessee Titans Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 8-2
  • ATS: 7-3
  • O/U: 6-4
  • ATS - Home: 3-2
  • ATS - Away: 4-1

D’Onta Foreman and Adrian Peterson have done their best to replace Henry since the NFL’s leading rusher was sidelined due to injury. Neither player has been able to run the ball particularly well though with Foreman averaging 3.7 YPC and Peterson averaging just 2.3 YPC over the last two games.

That has really impacted the effectiveness of Tannehill. He is not able to have the same success on play action that he does with a healthy Henry. Tannehill has thrown for just 356 yards with two touchdowns and an interception over the last two games, averaging 6.6 YPA in wins over the Rams and Saints.

Tennessee does have dangerous receivers in A.J. Brown and Julio Jones. Brown has been the top target, while Jones has been the big play threat (16.0 YPR). Unfortunately, Jones has been injured often this season, and he is currently on injured reserve with a hamstring injury. With Jones and Jeremy McNichols out, the Titans don’t have another receiver with over 200 receiving yards available.

The Titans will be without starting linebackers Bud Dupree, Rashaan Evans, and David Long Jr. this week. Starters Jeffery Simmons, Harold Landry III, and Janoris Jenkins are all questionable, so this defense could be very short-handed.

Tennessee has covered the spread in four of its last five home games when facing Houston. (AP)

Inside the Stats - Houston Texans

  • Record: 1-8
  • Division Standing: 4th - AFC South
  • Points Scored: 128
  • Points Allowed: 258
  • PS/G: 14.2 (32nd)
  • PA/G: 28.7 (29th)

Inside the Stats - Tennessee Titans

  • Record: 8-2
  • Division Standing: 1st - AFC South
  • Points Scored: 278
  • Points Allowed: 232
  • PS/G: 27.8 (5th)
  • PA/G: 23.2 (15th)

Key Players to Watch

  • HOU: Tyrod Taylor - QB (55/87, 656 yards, 3 TD, 3 INT)
  • HOU: Brandin Cooks - WR (57 catches, 641 yards, 2 TD)
  • TEN: Ryan Tannehill - QB (210/316, 2,358 yards, 12 TD, 8 INT)
  • TEN: A.J. Brown - WR (41 catches, 567 yards, 3 TD)

Houston Texans vs. Tennessee Titans Betting Conclusion

Tennessee is in a bad spot here. Houston is one of the worst teams in the NFL, but the Titans are missing a lot of their best players and might be looking ahead to next week’s clash with New England. The Texans should keep this close throughout the full 60 minutes.

Houston Texans vs. Tennessee Titans Betting Trends

  • Tennessee has won six straight games.
  • Tennessee has covered the spread in four of its last five home games when facing Houston.
  • Houston has gone UNDER the point total in six of its last seven road games.
  • The point total has gone OVER in four of the last five meetings.

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