College Football Odds Week 1: Mercer vs Ole Miss Lines, Spreads, Betting Trends
| Matchup | Spread | Total | Moneyline |
|---|
College football odds for Week 1 are on the board and receiving plenty of attention as we tackle all the major storylines of the weekend. The Mercer Bears and Ole Miss Rebels meet at Vaught-Hemingway Stadium in Oxford on Saturday, September 2 at 2:00 p.m. ET on ESPN+.
Here's everything you need to know about the college football odds for the Week 1 game between Mercer and Ole Miss: the opening lines, spreads, betting trends and more. Check back regularly for updates.
Mercer vs No. 22 Mississippi Odds
- Opening point spread: TBA
- Opening moneyline: TBA
- Opening total: TBA
- Time: 2 p.m. ET Saturday (ESPN+/SECN+)
UPDATE 4 P.M. ET MONDAY: Ole Miss went 8-5 SU/4-8-1 ATS last season, ending on a 1-5 SU purge (1-4-1 ATS), including 0-4 SU in its last four games. The Rebels finished with a 42-25 loss as 4.5-point favorites vs. Texas Tech in the Texas Bowl.
Mercer, from the FCS Southern Conference, opened its season with a 17-7 home win over North Alabama.
There are no odds yet on Mercer-Ole Miss.
College Football News
-
COLLEGE-FOOTBALL MAR 2, 20262026-27 CFP Futures Odds: Ohio State Opens as Favorite
- COLLEGE-FOOTBALL DEC 27, 2025
Who Will Be Michigan’s Next Head Coach?: Michigan Next Head Coach Odds
- COLLEGE-FOOTBALL OCT 23, 2025
NCAA Division I Executives Vote To Remove Ban on College Athletes Betting on Professional Sports
- COLLEGE-FOOTBALL OCT 8, 2025
Penn State and Texas Go Down: How This Affects Their Championship Odds/AP Polling
- COLLEGE-FOOTBALL JAN 19, 2026
College Football Playoff Championship Game Odds: Lines, Spreads, Betting Trends for Miami vs. Indiana
- COLLEGE-FOOTBALL JAN 16, 2026
National Championship Prediction, Odds: Stats Back First-Half Under
