College Football Odds Week 10: Florida State vs Pittsburgh Lines, Spreads, Betting Trends
Matchup | Spread | Total | Moneyline |
---|
Florida State looks to stay undefeated as the Seminoles head to Pittsburgh for an ACC contest in Week 10 of college football. Betting odds see the Seminoles as 21.5-point road favorites against the Panthers. Coverage begins from Acrisure Stadium on Saturday, November 4 at 3:30 p.m. ET on ESPN.
Here's everything you need to know about the college football odds for Week 10 Florida State vs Pittsburgh: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.
No. 4 Florida State vs Pittsburgh Odds

- Opening point spread: Florida State -23
- Opening moneyline: Florida State -1700/Pittsburgh +950
- Opening total: Over/Under 51 points scored
- Time: 3:30 p.m. ET Saturday (ESPN)
UPDATE 1:30 P.M. ET FRIDAY: The Seminoles are pinned to -21.5 at BetMGM, with no line movement all week. Spread tickets are almost 3/1 and spread money 2.5/1 on Florida State.
The total opened at 51.5 and on Wednesday afternoon went to 51/50.5. The Over is taking 68% of tickets, while 57% of money is on the Under.
UPDATE 3 P.M. ET MONDAY: Florida State (8-0 SU/6-2 ATS) has covered three in a row and four of its last five. In Week 9, the Seminoles plowed past Wake Forest 41-16 laying 21 points on the highway.
Pittsburgh (2-6 SU/1-7 ATS) got steamrolled at Notre Dame 58-7 as a 21-point pup.
The Florida State-Pitt line has seen a few moves already at Caesars. The Seminoles opened -23 Sunday afternoon, dropped to -21.5 within a couple hours and to -21 (-115) by Sunday night. Florida State is now -21.5.
Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 10 Report containing spreads, lines, and trends for every Top 25 matchup.
College Football News
- COLLEGE-FOOTBALL OCT 12, 2025
2025 College Football Odds Week 8: Lines, Spreads, Betting Trends on Biggest Games
- COLLEGE-FOOTBALL OCT 9, 2025
NCAA Division I Executives Vote To Remove Ban on College Athletes Betting on Professional Sports
- COLLEGE-FOOTBALL OCT 8, 2025
Penn State and Texas Go Down: How This Affects Their Championship Odds/AP Polling
- COLLEGE-FOOTBALL SEP 2, 2025
College Football’s Most Handsome Coaches
- COLLEGE-FOOTBALL OCT 9, 2025
2025-26 CFP Futures Odds: Ohio State Still On Top, Penn State Tumbles
- COLLEGE-FOOTBALL AUG 9, 2025
SuperContest Expands From NFL, Adds SuperContest College