College Football Odds Week 4: USC vs Arizona State Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Arizona State vs
+34.5 (-105)
-34.5 (-115)
o62.5 (-105)
u62.5 (-115)

The Week 4 college football odds have emerged and are drawing significant attention as we dive into the weekend's major narratives. Arizona State takes on USC in a Pac-12 clash at Mountain America Stadium in Temple, Arizona on September 23 at 10:30 p.m. ET, with the game broadcast on FOX.

Here's everything you need to know about the college football odds for Week 4 USC vs. Arizona State : the opening lines, spreads, betting trends and more. Check back regularly for updates.

No. 5 USC vs Arizona State Odds

  • Opening point spread: USC -30.5
  • Opening moneyline: Southern Cal -80000/Arizona State +2750
  • Opening total: Over/Under 62 points scored
  • Time: 10:30 p.m. ET (FOX)

UPDATE 2 P.M. ET FRIDAY: USC opened -34.5 at BetMGM, spent a few hours Tuesday at -33.5, then climbed to -34.5 (-115). The huge number isn't scaring off early bettors, with ticket count 3/1 and money 9/1 on the Trojans.

The total moved from 61.5 to 62.5 today. Current splits aren't available.

UPDATE 3:30 P.M. ET MONDAY: Southern Cal (3-0 SU/2-1 ATS) has piled up 178 points through three games, and didn't even face an FCS team to do so. The Trojans, who had a Week 3 bye, stomped Stanford 55-10 as 28.5-point home favorites in Week 2.

Arizona State (1-2 SU/0-3 ATS) appears to be dreadful thus far. In Week 3, the Sun Devils were 4-point home underdogs to Fresno State and got blanked 29-0.

After opening -30.5 Sunday afternoon, USC shot out to -34 by this morning at Caesars. The Trojans are now -33.5.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 4 Report containing spreads, lines, and trends for every Top 25 matchup.