College Football Odds Week 6: Syracuse vs North Carolina Lines, Spreads, Betting Trends
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Week 6 of college football showcases an ACC matchup between Syracuse and North Carolina. Betting odds have the Tar Heels as 8.5-point home favorites over the Orange. Coverage begins from Chapel Hill on Saturday, October 7 at 3:30 p.m. ET on ESPN.
Here's everything you need to know about the college football odds for Week 6 Syracuse vs North Carolina: the opening lines, spreads, betting trends and more. Check back regularly for updates.
Syracuse vs No. 14 North Carolina Odds

- Opening point spread: North Carolina -9.5
- Opening moneyline: North Carolina -420/Syracuse +320
- Opening total: Over/Under 58 points scored
- Time: 3:30 p.m. ET Saturday
UPDATE 1 P.M. ET SATURDAY: North Carolina remains -10 today at BetMGM (see previous update below), but betting splits have tightened. Spread tickets are now about 2/1 and spread money 2.5/1 on the Tar Heels.
Likewise, the total hasn't moved off 59.5, with tickets 2/1-plus and money 4/1 on the Over.
UPDATE 1 P.M. ET FRIDAY: The Tar Heels hit BetMGM's college football odds Week 6 market as 8.5-point favorites Sunday. On Thursday, the number jumped straight to -9.5, and this morning, Carolina went to -10.
Spread tickets are running 3/1 and spread money 9/1 on North Carolina.
The total climbed from 58.5 to 60.5 by Tuesday and has been at 59.5 since Wednesday. The Over is drawing 60% of bets/77% of cash.
UPDATE 3 P.M. ET MONDAY: North Carolina (4-0 SU/3-1 ATS) rolled past Pittsburgh 41-24 as a 7-point fave in Week 4. The Tar Heels then had a bye in Week 5.
Syracuse (4-1 SU/3-1-1 ATS) saw its 4-0 start to the regular season end in Week 5. The Orange were 7-point home 'dogs to Clemson and lost 31-14.
Caesars Sports has already dialed Carolina down a point in the college football odds Week 6 market. The Tar Heels dipped to -9 Sunday evening, then -8.5 this morning.
Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 6 Report containing spreads, lines, and trends for every Top 25 matchup.
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