Sign Up Subscribe
Featured Last Updated Oct 14 2026, 1:55 PM

Mississippi State vs. LSU Prediction: LSU Gets Back on Track

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
14 minute read
Mississippi State vs. LSU Prediction: LSU Gets Back on Track

The Mississippi State Bulldogs will take on the LSU Tigers in this week's college football action. Kickoff is set for 12:00 p.m. EST at Tiger Stadium in Baton Rouge, LA. The game will be broadcast live on ESPN. Here's everything you need to know about Mississippi State vs. LSU odds, the latest college football spreads, college football over/unders and more.

MSST @ LSU Odds

  • Full Game
  • 1H
  • 1Q
  • 3Q
  • 4Q
  • 2Q
  • Spread
  • Total
  • Moneyline
Mississippi State Bulldogs 205 Mississippi State
+12.5 -115 +8.5 -112 + +8.5 -112 + +8.5 -112 + +8.5 -113 + +8.5 -112 + +8.5 -115 + +7.5 -122 + +14.5 -112  
LSU Tigers 206 LSU
-12.5 -105 -8.5 -108 + -8.5 -108 + -8.5 -108 + -8.5 -108 + -8.5 -108 + -8.5 -115 + -7.5 -109 + -14.5 -108  
Mississippi State Bulldogs 205 Mississippi State
o59.5 -110 o30.5 -117 + o30.5 -110 + o30.5 -105 + o30.5 -112 + o30.5 -118 + o30.5 -115 + o30.5 -121 + o57.5 -108  
LSU Tigers 206 LSU
u59.5 -110 u30.5 -103 + u30.5 -108 + u30.5 -115 + u30.5 -109 + u30.5 -104 + u30.5 -115 + u30.5 -110 + u57.5 -112  
Mississippi State Bulldogs 205 Mississippi State
+350 +310 + +320 + +310 + +295 + +310 + N/A +285 + +440  
LSU Tigers 206 LSU
-455 -390 + -400 + -395 + -390 + -430 + N/A -400 + -600  
Mississippi State Bulldogs 205 Mississippi State
+12.5 -115 +3.5 -120 + +3.5 -110 + +3.5 -120 + N/A +3.5 -104 + +3.5 -110 + +3.5 -117 + +14.5 -112  
LSU Tigers 206 LSU
-12.5 -105 -3.5 -110 + -3.5 -118 + -3.5 -110 + N/A -3.5 -118 + -3.5 -120 + -3.5 -120 + -14.5 -108  
Mississippi State Bulldogs 205 Mississippi State
o59.5 -110 o13.5 -120 + o13.5 -120 + o13.5 -115 + N/A o13.5 -128 + o13.5 -125 + o13.5 -130 + o57.5 -108  
LSU Tigers 206 LSU
u59.5 -110 u13.5 -110 + u13.5 -105 + u13.5 -115 + N/A u13.5 +106 + u13.5 -105 + u13.5 -103 + u57.5 -112  
Mississippi State Bulldogs 205 Mississippi State
+350 +195 + +210 + +195 + N/A +225 + N/A +200 + +440  
LSU Tigers 206 LSU
-455 -260 + -275 + -260 + N/A -270 + N/A -275 + -600  
Mississippi State Bulldogs 205 Mississippi State
+12.5 -115 N/A N/A +6.5 -108 + N/A N/A N/A N/A +14.5 -112  
LSU Tigers 206 LSU
-12.5 -105 N/A N/A -6.5 -112 + N/A N/A N/A N/A -14.5 -108  
Mississippi State Bulldogs 205 Mississippi State
o59.5 -110 N/A N/A o27.5 even + N/A N/A N/A N/A o57.5 -108  
LSU Tigers 206 LSU
u59.5 -110 N/A N/A u27.5 -120 + N/A N/A N/A N/A u57.5 -112  
Mississippi State Bulldogs 205 Mississippi State
+350 N/A N/A +250 + N/A N/A N/A N/A +440  
LSU Tigers 206 LSU
-455 N/A N/A -310 + N/A N/A N/A N/A -600  
Mississippi State Bulldogs 205 Mississippi State
+12.5 -115 N/A N/A +3.5 -130 + N/A +3.5 -110 + N/A N/A +14.5 -112  
LSU Tigers 206 LSU
-12.5 -105 N/A N/A -3.5 even + N/A -3.5 -110 + N/A N/A -14.5 -108  
Mississippi State Bulldogs 205 Mississippi State
o59.5 -110 o13.5 -105 + N/A o13.5 -105 + N/A o13.5 -112 + N/A N/A o57.5 -108  
LSU Tigers 206 LSU
u59.5 -110 u13.5 -135 + N/A u13.5 -125 + N/A u13.5 -108 + N/A N/A u57.5 -112  
Mississippi State Bulldogs 205 Mississippi State
+350 +190 + N/A +195 + N/A +215 + N/A N/A +440  
LSU Tigers 206 LSU
-455 -260 + N/A -260 + N/A -290 + N/A N/A -600  
Mississippi State Bulldogs 205 Mississippi State
+12.5 -115 +2.5 -120 + N/A +2.5 even + N/A +2.5 -100 + N/A N/A +14.5 -112  
LSU Tigers 206 LSU
-12.5 -105 -2.5 -120 + N/A -2.5 -130 + N/A -2.5 -122 + N/A N/A -14.5 -108  
Mississippi State Bulldogs 205 Mississippi State
o59.5 -110 o13.5 -145 + N/A o13.5 -145 + N/A o13.5 -144 + N/A N/A o57.5 -108  
LSU Tigers 206 LSU
u59.5 -110 u13.5 +105 + N/A u13.5 +114 + N/A u13.5 +118 + N/A N/A u57.5 -112  
Mississippi State Bulldogs 205 Mississippi State
+350 +160 + N/A +180 + N/A +186 + N/A N/A +440  
LSU Tigers 206 LSU
-455 -220 + N/A -238 + N/A -225 + N/A N/A -600  
Mississippi State Bulldogs 205 Mississippi State
+12.5 -115 N/A N/A +4.5 -115 + N/A +5.5 -110 + N/A N/A +14.5 -112  
LSU Tigers 206 LSU
-12.5 -105 N/A N/A -4.5 -115 + N/A -5.5 -110 + N/A N/A -14.5 -108  
Mississippi State Bulldogs 205 Mississippi State
o59.5 -110 o17.5 +115 + N/A o16.5 -135 + N/A o17.5 +114 + N/A N/A o57.5 -108  
LSU Tigers 206 LSU
u59.5 -110 u17.5 -155 + N/A u16.5 +105 + N/A u17.5 -140 + N/A N/A u57.5 -112  
Mississippi State Bulldogs 205 Mississippi State
+350 +215 + N/A +240 + N/A +250 + N/A N/A +440  
LSU Tigers 206 LSU
-455 -310 + N/A -330 + N/A -310 + N/A N/A -600  

The LSU Tigers opened as a -10 point favorite over Mississippi State. The total is set at over/under 57.5 total points scored by both teams combined.

Google Preferred Source

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the Polymarket promo code!

Updated on 10/14/26

bet365
Bet $10, Get $200 in Bonus Bets Win or Lose!
Bonus Code
VIBONUS
Claim $200
Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Must be 21+ and physically present where bet365 operates. Please gamble responsibly. New customers only. Place qualifying bets of $10 or more to get $200 in Bonus Bets. Deposit required. Bonus bets are non-withdrawable and expire 7 days after receipt. Bonus bet wager excluded from returns. Time limits, min. Odds, and T&Cs apply. This code is used for marketing and tracking purposes only. Void where prohibited. Not eligible in IL, IN, TN, & WV.

Mississippi State vs. LSU Prediction

LSU is in a tier of it's own when compared to Mississippi State. LSU ranks 3rds in net adjusted EPA/play, whereas Mississippi State ranks 23rd.

Where the LSU offense shines is in late downs, where they rank 17th in late-down success rate. LSU's defense ranks in the 99th percentile in success rate allowed, with a particular strength against the run game. They are also in a league of their own when it comes to creating defensive havoc.

This will likely be Kamario Taylor's toughest test, and I do not think he will pass it.

Updated on 10/14/26

Polymarket
Deposit $10, Get a $25 Trading Bonus!
Bonus Code
INSIDER
Claim $25
18+ Only. Restrictions and eligibility requirements apply. Not available in all jurisdictions. Trading is risky. 100% loss can occur. See polymarket.com/tos for more information. The Polymarket US App serves as an independent software provider and affiliate of Polymarket US and Polymarket Clearing, the CFTC-regulated exchange and clearing organization.

Mississippi State vs. LSU Prediction: LSU Tigers -14.5 (-108)

(Pick from Dylan Wilkerson)

Looking for more college football predictions? Check out our free college football picks and our premium subscription for the best picks!

Featured News

Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
•