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Featured Last Updated Oct 14 2026, 2:15 PM

Missouri vs. Ole Miss Prediction: Missouri Beats Ole Miss With Their Defense

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
14 minute read
Missouri vs. Ole Miss Prediction: Missouri Beats Ole Miss With Their Defense

The Missouri Tigers will take on the Ole Miss Rebels in this week's college football action. Kickoff is set for 3:30 p.m. EST at Vaught-Hemingway Stadium in Oxford, MS. The game will be broadcast live on SEC Network. Here's everything you need to know about Missouri vs. Ole Miss odds, the latest college football spreads, college football over/unders and more.

MIZ @ MISS Odds

  • Full Game
  • 1Q
  • 1H
  • 4Q
  • 3Q
  • 2Q
  • Spread
  • Total
  • Moneyline
Missouri Tigers 197 Missouri
+6 -105 +2.5 -115 + +2.5 -110 + +1.5 -115 + N/A +2.5 -108 + +2.5 -115 +2.5 -115 + +6 -112  
Ole Miss Rebels 198 Ole Miss
-6 -115 -2.5 -115 + -2.5 -115 + -1.5 -115 + N/A -2.5 -114 + -2.5 -115 -2.5 -115 + -6 -108  
Missouri Tigers 197 Missouri
o57.5 -110 o13.5 -110 + o13.5 -115 + o13.5 -125 + N/A o13.5 -108 + o13.5 -115 + o13.5 -108 + o59.5 -102  
Ole Miss Rebels 198 Ole Miss
u57.5 -110 u13.5 -120 + u13.5 -112 + u13.5 -105 + N/A u13.5 -114 + u13.5 -115 + u13.5 -122 + u59.5 -118  
Missouri Tigers 197 Missouri
+190 +150 + +155 + +154 + N/A +158 + N/A +150 + +185  
Ole Miss Rebels 198 Ole Miss
-230 -190 + -210 + -200 + N/A -186 + N/A -195 + -225  
Missouri Tigers 197 Missouri
+6 -105 +3.5 -103 + +3.5 -102 + +3.5 -108 + +3.5 -103 + +3.5 -104 + +3.5 -115 + +3.5 -117 + +6 -112  
Ole Miss Rebels 198 Ole Miss
-6 -115 -3.5 -117 + -3.5 -115 + -3.5 -112 + -3.5 -120 + -3.5 -118 + -3.5 -115 + -3.5 -118 + -6 -108  
Missouri Tigers 197 Missouri
o57.5 -110 o30.5 -111 + o30.5 -105 + o30.5 -110 + o30.5 -105 + o30.5 -100 + o30.5 -115 + o30.5 -107 + o59.5 -102  
Ole Miss Rebels 198 Ole Miss
u57.5 -110 u30.5 -109 + u30.5 -115 + u30.5 -110 + u30.5 -117 + u30.5 -122 + u30.5 -115 + u30.5 -125 + u59.5 -118  
Missouri Tigers 197 Missouri
+190 +165 + +160 + +160 + +161 + +166 + N/A +160 + +185  
Ole Miss Rebels 198 Ole Miss
-230 -200 + -190 + -192 + -200 + -205 + N/A -210 + -225  
Missouri Tigers 197 Missouri
+6 -105 +1.5 -155 + N/A +0.5 -130 + N/A +1.5 -140 + N/A N/A +6 -112  
Ole Miss Rebels 198 Ole Miss
-6 -115 -1.5 +115 + N/A -0.5 even + N/A -1.5 +116 + N/A N/A -6 -108  
Missouri Tigers 197 Missouri
o57.5 -110 o14.5 -105 + N/A o14.5 -120 + N/A o14.5 -104 + N/A N/A o59.5 -102  
Ole Miss Rebels 198 Ole Miss
u57.5 -110 u14.5 -135 + N/A u14.5 -110 + N/A u14.5 -118 + N/A N/A u59.5 -118  
Missouri Tigers 197 Missouri
+190 -105 + N/A +105 + N/A +108 + N/A N/A +185  
Ole Miss Rebels 198 Ole Miss
-230 -135 + N/A -135 + N/A -126 + N/A N/A -225  
Missouri Tigers 197 Missouri
+6 -105 N/A N/A +0.5 -125 + N/A +1.5 -138 + N/A N/A +6 -112  
Ole Miss Rebels 198 Ole Miss
-6 -115 N/A N/A -0.5 -105 + N/A -1.5 +112 + N/A N/A -6 -108  
Missouri Tigers 197 Missouri
o57.5 -110 o13.5 -105 + N/A o13.5 -110 + N/A o13.5 -108 + N/A N/A o59.5 -102  
Ole Miss Rebels 198 Ole Miss
u57.5 -110 u13.5 -135 + N/A u13.5 -120 + N/A u13.5 -112 + N/A N/A u59.5 -118  
Missouri Tigers 197 Missouri
+190 +110 + N/A +130 + N/A +112 + N/A N/A +185  
Ole Miss Rebels 198 Ole Miss
-230 -150 + N/A -166 + N/A -142 + N/A N/A -225  
Missouri Tigers 197 Missouri
+6 -105 N/A N/A +2.5 -108 + N/A N/A N/A N/A +6 -112  
Ole Miss Rebels 198 Ole Miss
-6 -115 N/A N/A -2.5 -112 + N/A N/A N/A N/A -6 -108  
Missouri Tigers 197 Missouri
o57.5 -110 N/A N/A o28.5 even + N/A N/A N/A N/A o59.5 -102  
Ole Miss Rebels 198 Ole Miss
u57.5 -110 N/A N/A u28.5 -120 + N/A N/A N/A N/A u59.5 -118  
Missouri Tigers 197 Missouri
+190 N/A N/A +136 + N/A N/A N/A N/A +185  
Ole Miss Rebels 198 Ole Miss
-230 N/A N/A -162 + N/A N/A N/A N/A -225  
Missouri Tigers 197 Missouri
+6 -105 N/A N/A +0.5 -115 + N/A +2.5 -110 + N/A N/A +6 -112  
Ole Miss Rebels 198 Ole Miss
-6 -115 N/A N/A -0.5 -115 + N/A -2.5 -110 + N/A N/A -6 -108  
Missouri Tigers 197 Missouri
o57.5 -110 o16.5 -135 + N/A o16.5 -140 + N/A o16.5 -128 + N/A N/A o59.5 -102  
Ole Miss Rebels 198 Ole Miss
u57.5 -110 u16.5 -105 + N/A u16.5 +110 + N/A u16.5 +104 + N/A N/A u59.5 -118  
Missouri Tigers 197 Missouri
+190 +115 + N/A +114 + N/A +138 + N/A N/A +185  
Ole Miss Rebels 198 Ole Miss
-230 -155 + N/A -145 + N/A -162 + N/A N/A -225  

The Ole Miss Rebels opened as a -6.5 point favorite over Missouri. The total is set at over/under 51.5 total points scored by both teams combined.

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Updated on 10/14/26

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Missouri vs. Ole Miss Prediction

Missouri has impressed me this season. They rank in the 90th percentile for EPA allowed and 94th percentile in success rate allowed. They create havoc both up front and in the secondary, which could cause some issues for Trinidad Chambliss and this Ole Miss offense.

Ole Miss' defense leaves a lot to be desired, ranking 90th in defensive success rate allowed, with a particular weakness against the rush. Ole Miss' typical operation consists of hero-ball from Chambliss, and I don't think that will be enough in this matchup.

Updated on 10/14/26

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Missouri vs. Ole Miss Prediction: Missouri Tigers Moneyline (+185)

(Pick from Dylan Wilkerson)

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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