Sign Up Subscribe
Featured Last Updated Nov 23 2025, 5:35 PM

Michigan vs. Ohio State Prediction: Wolverines Keep it Close

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
Michigan vs. Ohio State Prediction: Wolverines Keep it Close

Image Credit: Adam Cairns/Columbus Dispatch / USA TODAY NETWORK via Imagn Images

OSU @ MICH Odds

  • Full Game
  • 4Q
  • Spread
  • Total
  • Moneyline
Ohio State Buckeyes 363 Ohio State
-5.5 -110 N/A N/A -0.5 +105 N/A N/A N/A N/A N/A -10.5 -110  
Michigan Wolverines 364 Michigan
+5.5 -110 N/A N/A +0.5 -135 N/A N/A N/A N/A N/A +10.5 -110  
Ohio State Buckeyes 363 Ohio State
o47.5 -110 N/A N/A o9.5 -130 N/A N/A N/A N/A N/A o44.5 -110  
Michigan Wolverines 364 Michigan
u47.5 -110 N/A N/A u9.5 even N/A N/A N/A N/A N/A u44.5 -110  
Ohio State Buckeyes 363 Ohio State
-198 N/A N/A -135 N/A N/A N/A N/A N/A -440  
Michigan Wolverines 364 Michigan
+164 N/A N/A +105 N/A N/A N/A N/A N/A +330  

The Ohio State Buckeyes will take on the Michigan Wolverines in this week's college football action. Kickoff is set for 12:00 p.m. EST at Michigan Stadium in Ann Arbor, Mich. The game will be broadcast live on FOX. Here's everything you need to know about Ohio State vs. Michigan odds, the latest college football spreads, college football over/unders and more.

The Ohio State Buckeyes opened as a -10.5 point favorite over Michigan. The total is set at over/under 44.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 11/23/25

bet365
Bet $5, Get $150 in Bonus Bets Win or Lose!
Bonus Code
VIBONUS
Claim $150
Deposit Required. Paid in Bonus Bets. Bonus Bets wager excluded from returns. New Customers Only. T&Cs, time limits, and exclusions apply. 21+ (18+ in KY). Gambling Problem? Call 1-800-GAMBLER. Available in AZ, CO, IA, IL, IN, KS, KY, LA, MD, NC, NJ, OH, PA, TN, VA only. Bet $5 and Get $150 in Bonus Bets at bet365. Minimum odds -500 of greater.

Michigan vs. Ohio State State Prediction

From a statistical point, this game should be much closer than the 11.5 point spread indicates. Both teams have played a similar strength of schedule to date. Michigan has found a lot of success in the run game this year ranking 10th in EPA per rush, and Bryce Underwood is even able to rush the ball if needed.

Michigan's defense is very strong, as it usually is. You can't talk about this game without mentioning Ryan Day's issues against Michigan historically. Records go out the window for this game, and I think it is a close one.

Michigan vs. Ohio State Prediction: Michigan Wolverines +11.5 (-110)

(Pick from Dylan Wilkerson)

Looking for more college football predictions? Check out our free college football picks and our premium subscription for the best picks!

Google Preferred Source

What Time is the Michigan vs. Ohio State Game?

The Wolverines will take on the Buckeyes at 12:00 PM ET on Saturday, November 29th.

Where is the Michigan vs. Ohio State Game Being Played?

This game is going to be played at Michigan Stadium in Ann Arbor, Mich.

How Can I Watch The Michigan vs. Ohio State Game?

You can watch Michigan vs. Ohio State on FOX.

Can Michigan State Beat Ohio State?

Absolutely! Michigan State is an underdog in this game, but anything can happen in college football!

Featured News

Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
•