Ole Miss vs. Mississippi State Prediction: Ole Miss Strolls Into Playoffs
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The Ole Miss will take on the Mississippi St in this week's college football action. Kickoff is set for 12:00 p.m. EST at Davis Wade Stadium at Scott Field in Starkville, Miss. The game will be broadcast live on ABC. Here's everything you need to know about Ole Miss vs. Mississippi St odds, the latest college football spreads, college football over/unders and more.

The Ole Miss Rebels opened as a -8.5 point favorite over Mississippi St. The total is set at over/under 62.5 total points scored by both teams combined.
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Updated on 11/23/25

Ole Miss vs. Mississippi State Prediction
Both of these teams like to play fast, averaging over 75 offensive snaps per game. This benefits Ole Miss high-powered offense that ranks 11th in offensive pass success rate. Ole Miss also has the benefit of coming off of a bye. They will be well rested for this rivalry matchup. Mississippi State's offense is average across the board and their defensive weakness against the run gives a viable path to Ole Miss domination.

Ole Miss vs. Mississippi State Prediction: Ole Miss Rebels -7.5 (-115)
(Pick from Dylan Wilkerson)
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What Time is the Ole Miss vs. Mississippi State Game?
The Bulldogs will take on the Rebels at 12:30 PM ET on Friday, November 28th.
Where is the Ole Miss vs. Mississippi State Game Being Played?
This game is going to be played at Davis Wade Stadium at Scott Field in Starkville, Miss.
How Can I Watch The Ole Miss vs. Mississippi State Game?
You can watch Ole Miss vs. Mississippi State on ESPN.
Can Mississippi State Beat Ole Miss?
Absolutely! Missippi State is an underdog in this game, but anything can happen in college football!
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