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Featured Last Updated Oct 14 2026, 2:52 PM

Ohio State vs. Indiana Prediction: Low Scoring Big Ten Affair

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
14 minute read
Ohio State vs. Indiana Prediction: Low Scoring Big Ten Affair

The Ohio State Buckeyes will take on the Indiana Hoosiers in this week's college football action. Kickoff is set for 12:00 p.m. EST at Memorial Stadium in Bloomington, IN. The game will be broadcast live on ABC. Here's everything you need to know about Ohio State vs. Indiana odds, the latest college football spreads, college football over/unders and more.

OSU @ IU Odds

  • Full Game
  • 1Q
  • 1H
  • 3Q
  • 4Q
  • 2Q
  • Spread
  • Total
  • Moneyline
Ohio State Buckeyes 127 Ohio State
PK -110 -0.5 even + -0.5 +105 + -0.5 +110 + N/A -1.5 +114 + N/A -0.5 +105 + -1.5 +115 + -3.5 -108  
Indiana Hoosiers 128 Indiana
PK -110 +0.5 -130 + +0.5 -135 + +0.5 -140 + N/A +1.5 -138 + N/A +0.5 -140 + +1.5 -152 + +3.5 -112  
Ohio State Buckeyes 127 Ohio State
o48.5 -112 o10.5 +115 + o9.5 -150 + o9.5 -130 + N/A o10.5 +116 + N/A o10.5 +105 + o9.5 -150 + o51.5 even  
Indiana Hoosiers 128 Indiana
u48.5 -108 u10.5 -145 + u9.5 +115 + u9.5 even + N/A u10.5 -142 + N/A u10.5 -140 + u9.5 +112 + u51.5 -120  
Ohio State Buckeyes 127 Ohio State
-108 -160 + -150 + -160 + N/A -146 + N/A N/A -139 + -180  
Indiana Hoosiers 128 Indiana
-112 +125 + +120 + +124 + N/A +124 + N/A N/A +112 + +150  
Ohio State Buckeyes 127 Ohio State
PK -110 -2.5 -110 + -2.5 -110 + -2.5 -112 + -2.5 -108 + -2.5 -114 + N/A -2.5 -115 + -2.5 -115 + -3.5 -108  
Indiana Hoosiers 128 Indiana
PK -110 +2.5 -110 + +2.5 -108 + +2.5 -108 + +2.5 -113 + +2.5 -106 + N/A +2.5 -115 + +2.5 -114 + +3.5 -112  
Ohio State Buckeyes 127 Ohio State
o48.5 -112 o24.5 -102 + o24.5 -105 + o24.5 -102 + o24.5 -106 + o24.5 -108 + N/A o24.5 -105 + o24.5 -109 + o51.5 even  
Indiana Hoosiers 128 Indiana
u48.5 -108 u24.5 -118 + u24.5 -115 + u24.5 -118 + u24.5 -115 + u24.5 -112 + N/A u24.5 -125 + u24.5 -122 + u51.5 -120  
Ohio State Buckeyes 127 Ohio State
-108 -150 + -145 + -142 + -148 + -160 + N/A N/A -159 + -180  
Indiana Hoosiers 128 Indiana
-112 +125 + +120 + +120 + +121 + +130 + N/A N/A +123 + +150  
Ohio State Buckeyes 127 Ohio State
PK -110 N/A N/A -0.5 +105 + N/A -1.5 +118 + N/A N/A N/A -3.5 -108  
Indiana Hoosiers 128 Indiana
PK -110 N/A N/A +0.5 -135 + N/A +1.5 -144 + N/A N/A N/A +3.5 -112  
Ohio State Buckeyes 127 Ohio State
o48.5 -112 o10.5 +115 + N/A o10.5 +110 + N/A o10.5 +112 + N/A N/A N/A o51.5 even  
Indiana Hoosiers 128 Indiana
u48.5 -108 u10.5 -155 + N/A u10.5 -140 + N/A u10.5 -136 + N/A N/A N/A u51.5 -120  
Ohio State Buckeyes 127 Ohio State
-108 -160 + N/A -160 + N/A -146 + N/A N/A N/A -180  
Indiana Hoosiers 128 Indiana
-112 +120 + N/A +124 + N/A +114 + N/A N/A N/A +150  
Ohio State Buckeyes 127 Ohio State
PK -110 -1.5 +105 + N/A -0.5 -105 + N/A -1.5 +120 + N/A N/A N/A -3.5 -108  
Indiana Hoosiers 128 Indiana
PK -110 +1.5 -145 + N/A +0.5 -125 + N/A +1.5 -146 + N/A N/A N/A +3.5 -112  
Ohio State Buckeyes 127 Ohio State
o48.5 -112 o13.5 -115 + N/A o14.5 +105 + N/A o13.5 -112 + N/A N/A N/A o51.5 even  
Indiana Hoosiers 128 Indiana
u48.5 -108 u13.5 -125 + N/A u14.5 -135 + N/A u13.5 -108 + N/A N/A N/A u51.5 -120  
Ohio State Buckeyes 127 Ohio State
-108 -150 + N/A -145 + N/A -128 + N/A N/A N/A -180  
Indiana Hoosiers 128 Indiana
-112 +110 + N/A +114 + N/A +110 + N/A N/A N/A +150  
Ohio State Buckeyes 127 Ohio State
PK -110 N/A N/A -0.5 +110 + N/A -1.5 +104 + N/A N/A N/A -3.5 -108  
Indiana Hoosiers 128 Indiana
PK -110 N/A N/A +0.5 -140 + N/A +1.5 -128 + N/A N/A N/A +3.5 -112  
Ohio State Buckeyes 127 Ohio State
o48.5 -112 o14.5 +110 + N/A o14.5 even + N/A o14.5 +112 + N/A N/A N/A o51.5 even  
Indiana Hoosiers 128 Indiana
u48.5 -108 u14.5 -150 + N/A u14.5 -130 + N/A u14.5 -136 + N/A N/A N/A u51.5 -120  
Ohio State Buckeyes 127 Ohio State
-108 -150 + N/A -125 + N/A -142 + N/A N/A N/A -180  
Indiana Hoosiers 128 Indiana
-112 +110 + N/A -105 + N/A +120 + N/A N/A N/A +150  
Ohio State Buckeyes 127 Ohio State
PK -110 N/A N/A -2.5 -108 + N/A N/A N/A N/A N/A -3.5 -108  
Indiana Hoosiers 128 Indiana
PK -110 N/A N/A +2.5 -112 + N/A N/A N/A N/A N/A +3.5 -112  
Ohio State Buckeyes 127 Ohio State
o48.5 -112 N/A N/A o25.5 -108 + N/A N/A N/A N/A N/A o51.5 even  
Indiana Hoosiers 128 Indiana
u48.5 -108 N/A N/A u25.5 -112 + N/A N/A N/A N/A N/A u51.5 -120  
Ohio State Buckeyes 127 Ohio State
-108 N/A N/A -166 + N/A N/A N/A N/A N/A -180  
Indiana Hoosiers 128 Indiana
-112 N/A N/A +140 + N/A N/A N/A N/A N/A +150  

The Ohio State Buckeyes opened as a -3.5 point favorite over Indiana. The total is set at over/under 51.5 total points scored by both teams combined.

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Updated on 10/14/26

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Ohio State vs. Indiana Prediction

Both of these teams play relatively slow, with the Buckeyes averaging just under 72 offensive snaps per game and the Hoosiers averaging under 62 offensive snaps per game. Both teams also have a higher rush rate than college football average.

This overall favorability to run the ball and play slow on offense will lead to a low scoring Big Ten affair.

Updated on 10/14/26

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Ohio State vs. Indiana Prediction: Ohio State Buckeyes @ Indiana Hoosiers u51.5 (-120)

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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