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Oklahoma vs. Michigan Prediction: Michigan Keeps it Close After Disaster

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
14 minute read
Oklahoma vs. Michigan Prediction: Michigan Keeps it Close After Disaster

Updated on 10/25/26

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The Oklahoma Sooners will take on the Michigan Wolverines in this week's college football action. Kickoff is set for 12:00 p.m. EST at Michigan Stadium in Ann Arbor, MI. The game will be broadcast live on FOX. Here's everything you need to know about Oklahoma vs. Michigan odds, the latest college football spreads, college football over/unders and more.

OU @ MICH Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
Oklahoma Sooners 319 Oklahoma
+2.5 -110 -3 -110 -3.5 even -3.5 +102 -3.5 +102 -3.5 +102 -2.5 -125 -3.5 -105 -5.5 -108  
Michigan Wolverines 320 Michigan
-2.5 -110 +3 -110 +3.5 -120 +3.5 -122 +3.5 -124 +3.5 -124 +2.5 -105 +3.5 -125 +5.5 -112  
Final
Oklahoma Sooners 319 Oklahoma
o45.5 -115 o21.5 -110 o21.5 even o21.5 -102 o21.5 -105 o21.5 -110 o21.5 -110 o21.5 -105 o43.5 -112  
Michigan Wolverines 320 Michigan
u45.5 -105 u21.5 -110 u21.5 -120 u21.5 -118 u21.5 -117 u21.5 -110 u21.5 -120 u21.5 -125 u43.5 -108  
Final
Oklahoma Sooners 319 Oklahoma
+120 -185 -175 -180 -179 -178 N/A N/A -225  
Michigan Wolverines 320 Michigan
-142 +155 +145 +150 +145 +146 N/A N/A +185  
Final
Oklahoma Sooners 319 Oklahoma
+2.5 -110 -0.5 even -0.5 even -0.5 +105 N/A -1.5 +102 -0.5 -105 -0.5 +105 -5.5 -108  
Michigan Wolverines 320 Michigan
-2.5 -110 +0.5 -130 +0.5 -130 +0.5 -135 N/A +1.5 -126 +0.5 -125 +0.5 -140 +5.5 -112  
Final
Oklahoma Sooners 319 Oklahoma
o45.5 -115 o9.5 -125 o8.5 -115 o9.5 -125 N/A o9.5 -114 o10.5 even o9.5 -115 o43.5 -112  
Michigan Wolverines 320 Michigan
u45.5 -105 u9.5 -105 u8.5 -112 u9.5 -105 N/A u9.5 -108 u10.5 -130 u9.5 -115 u43.5 -108  
Final
Oklahoma Sooners 319 Oklahoma
+120 -180 -165 -154 N/A -160 N/A N/A -225  
Michigan Wolverines 320 Michigan
-142 +140 +130 +120 N/A +136 N/A N/A +185  
Final
Oklahoma Sooners 319 Oklahoma
+2.5 -110 N/A N/A -2.5 -110 N/A N/A N/A N/A -5.5 -108  
Michigan Wolverines 320 Michigan
-2.5 -110 N/A N/A +2.5 -110 N/A N/A N/A N/A +5.5 -112  
Final
Oklahoma Sooners 319 Oklahoma
o45.5 -115 N/A N/A o21.5 -102 N/A N/A o20.5 -130 N/A o43.5 -112  
Michigan Wolverines 320 Michigan
u45.5 -105 N/A N/A u21.5 -118 N/A N/A u20.5 -110 N/A u43.5 -108  
Final
Oklahoma Sooners 319 Oklahoma
+120 N/A N/A -170 N/A N/A N/A N/A -225  
Michigan Wolverines 320 Michigan
-142 N/A N/A +142 N/A N/A N/A N/A +185  
Final
Oklahoma Sooners 319 Oklahoma
+2.5 -110 N/A N/A -1.5 -110 N/A -1.5 -106 -0.5 -110 N/A -5.5 -108  
Michigan Wolverines 320 Michigan
-2.5 -110 N/A N/A +1.5 -120 N/A +1.5 -116 +0.5 -120 N/A +5.5 -112  
Final
Oklahoma Sooners 319 Oklahoma
o45.5 -115 o10 -120 N/A o10.5 -110 N/A o12.5 -128 o10.5 -125 N/A o43.5 -112  
Michigan Wolverines 320 Michigan
u45.5 -105 u10 -120 N/A u10.5 -120 N/A u12.5 +104 u10.5 -105 N/A u43.5 -108  
Final
Oklahoma Sooners 319 Oklahoma
+120 -190 N/A -175 N/A -156 N/A N/A -225  
Michigan Wolverines 320 Michigan
-142 +140 N/A +135 N/A +132 N/A N/A +185  
Final
Oklahoma Sooners 319 Oklahoma
+2.5 -110 N/A N/A -0.5 even N/A -1.5 +108 -0.5 +110 N/A -5.5 -108  
Michigan Wolverines 320 Michigan
-2.5 -110 N/A N/A +0.5 -130 N/A +1.5 -132 +0.5 -140 N/A +5.5 -112  
Final
Oklahoma Sooners 319 Oklahoma
o45.5 -115 o10 -120 N/A o8.5 -115 N/A o9.5 -116 o7.5 +105 N/A o43.5 -112  
Michigan Wolverines 320 Michigan
u45.5 -105 u10 -120 N/A u8.5 -115 N/A u9.5 -106 u7.5 -135 N/A u43.5 -108  
Final
Oklahoma Sooners 319 Oklahoma
+120 -200 N/A -175 N/A -164 N/A N/A -225  
Michigan Wolverines 320 Michigan
-142 +150 N/A +135 N/A +128 N/A N/A +185  
Final
Oklahoma Sooners 319 Oklahoma
+2.5 -110 -0.5 -120 N/A -0.5 even N/A -1.5 +104 -0.5 +110 N/A -5.5 -108  
Michigan Wolverines 320 Michigan
-2.5 -110 +0.5 -120 N/A +0.5 -130 N/A +1.5 -126 +0.5 -140 N/A +5.5 -112  
Final
Oklahoma Sooners 319 Oklahoma
o45.5 -115 o11.5 -120 N/A o12.5 -120 N/A o10.5 -102 o10.5 +110 N/A o43.5 -112  
Michigan Wolverines 320 Michigan
u45.5 -105 u11.5 -120 N/A u12.5 -110 N/A u10.5 -118 u10.5 -140 N/A u43.5 -108  
Final
Oklahoma Sooners 319 Oklahoma
+120 -175 N/A -145 N/A -152 N/A N/A -225  
Michigan Wolverines 320 Michigan
-142 +132 N/A +114 N/A +130 N/A N/A +185  

The Oklahoma Sooners opened as a -5.5 point favorite over Michigan. The total is set at over/under 43.5 total points scored by both teams combined.

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Updated on 10/25/26

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Oklahoma vs. Michigan Prediction

Last week's Michigan vs. Western Michigan game set the college football world ablaze. Aside from a clock discrepancy, Bryce Underwood failed to take a step up from last season's performance, and the offense looked stagnant. Michigan faces a tall task this week, facing off against one of the best defenses in college football.

A bright spot for Michigan (outside of that 13-minute WMU drive) was their defense. They generated 8 tackles for loss and had an 8% generated sack rate. Michigan's defense will be strong enough to keep John Mateer and this Oklahoma offense at bay.

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Oklahoma vs. Michigan Prediction: Michigan Wolverines +6.5

(Pick from Dylan Wilkerson)

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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