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Featured Last Updated Nov 21 2025, 11:31 AM

Oklahoma vs. Missouri: Prediction, Odds

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
Oklahoma vs. Missouri: Prediction, Odds

Image Credit: Gary Cosby Jr. via Imagn Images

MIZ @ OU Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Missouri Tigers 155 Missouri
+10.5 -110 +3.5 -110 + +4.5 -120 + +3.5 -112 + +3.5 -110 + +3.5 -112 + +3.5 -105 + +3.5 -105 +3.5 -113 + +6.5 -105  
Oklahoma Sooners 156 Oklahoma
-10.5 -110 -3.5 -110 + -4.5 even + -3.5 -108 + -3.5 -110 + -3.5 -108 + -3.5 -115 + -3.5 -125 -3.5 -110 + -6.5 -115  
Missouri Tigers 155 Missouri
o42.5 -110 o20.5 -115 + o20.5 -110 + o20.5 -112 + o20.5 -120 + o20.5 -115 + o21.5 even + o21.5 -105 o20.5 -117 + o42.5 -112  
Oklahoma Sooners 156 Oklahoma
u42.5 -110 u20.5 -105 + u20.5 -110 + u20.5 -108 + u20.5 -103 + u20.5 -105 + u21.5 -120 + u21.5 -125 u20.5 -112 + u42.5 -108  
Missouri Tigers 155 Missouri
+275 +170 + +180 + +180 + +172 + +164 + N/A N/A +155 + +210  
Oklahoma Sooners 156 Oklahoma
-345 -205 + -220 + -218 + -218 + -205 + N/A N/A -200 + -258  
Missouri Tigers 155 Missouri
+10.5 -110 +3 -120 + +2.5 -102 + +2.5 -105 + N/A +1.5 -112 + +1.5 -115 + +0.5 -115 +2.5 -129 + +6.5 -105  
Oklahoma Sooners 156 Oklahoma
-10.5 -110 -3 -110 + -2.5 -125 + -2.5 -125 + N/A -1.5 -112 + -1.5 -115 + -0.5 -115 -2.5 -103 + -6.5 -115  
Missouri Tigers 155 Missouri
o42.5 -110 o9.5 -110 + o8.5 -110 + o7.5 -110 + N/A o7.5 -112 + o9.5 -110 + o7.5 -115 o8.5 -115 + o42.5 -112  
Oklahoma Sooners 156 Oklahoma
u42.5 -110 u9.5 -120 + u8.5 -115 + u7.5 -120 + N/A u7.5 -114 + u9.5 -120 + u7.5 -115 u8.5 -113 + u42.5 -108  
Missouri Tigers 155 Missouri
+275 +175 + +180 + +165 + N/A +144 + N/A N/A +140 + +210  
Oklahoma Sooners 156 Oklahoma
-345 -225 + -235 + -215 + N/A -180 + N/A N/A -186 + -258  
Missouri Tigers 155 Missouri
+10.5 -110 N/A N/A +2.5 +102 + N/A N/A N/A N/A N/A +6.5 -105  
Oklahoma Sooners 156 Oklahoma
-10.5 -110 N/A N/A -2.5 -122 + N/A N/A N/A N/A N/A -6.5 -115  
Missouri Tigers 155 Missouri
o42.5 -110 N/A N/A o20.5 -112 + N/A N/A o20.5 -110 + N/A N/A o42.5 -112  
Oklahoma Sooners 156 Oklahoma
u42.5 -110 N/A N/A u20.5 -108 + N/A N/A u20.5 -120 + N/A N/A u42.5 -108  
Missouri Tigers 155 Missouri
+275 N/A N/A +154 + N/A N/A N/A N/A N/A +210  
Oklahoma Sooners 156 Oklahoma
-345 N/A N/A -185 + N/A N/A N/A N/A N/A -258  
Missouri Tigers 155 Missouri
+10.5 -110 N/A N/A +0.5 -140 + N/A +2.5 -110 + +1.5 -115 + N/A N/A +6.5 -105  
Oklahoma Sooners 156 Oklahoma
-10.5 -110 N/A N/A -0.5 +110 + N/A -2.5 -120 + -1.5 -115 + N/A N/A -6.5 -115  
Missouri Tigers 155 Missouri
o42.5 -110 o12.5 -115 + N/A o12.5 -115 + N/A o12.5 -106 + o10.5 -115 + N/A N/A o42.5 -112  
Oklahoma Sooners 156 Oklahoma
u42.5 -110 u12.5 -115 + N/A u12.5 -115 + N/A u12.5 -118 + u10.5 -115 + N/A N/A u42.5 -108  
Missouri Tigers 155 Missouri
+275 +145 + N/A +105 + N/A +136 + N/A N/A N/A +210  
Oklahoma Sooners 156 Oklahoma
-345 -180 + N/A -135 + N/A -170 + N/A N/A N/A -258  
Missouri Tigers 155 Missouri
+10.5 -110 N/A N/A +0.5 -120 + N/A +1.5 -120 + +0.5 -125 + N/A N/A +6.5 -105  
Oklahoma Sooners 156 Oklahoma
-10.5 -110 N/A N/A -0.5 -110 + N/A -1.5 -110 + -0.5 -105 + N/A N/A -6.5 -115  
Missouri Tigers 155 Missouri
o42.5 -110 o8.5 -115 + N/A o7.5 -115 + N/A o8.5 -118 + o7.5 -105 + N/A N/A o42.5 -112  
Oklahoma Sooners 156 Oklahoma
u42.5 -110 u8.5 -115 + N/A u7.5 -115 + N/A u8.5 -106 + u7.5 -125 + N/A N/A u42.5 -108  
Missouri Tigers 155 Missouri
+275 +160 + N/A +135 + N/A +154 + N/A N/A N/A +210  
Oklahoma Sooners 156 Oklahoma
-345 -200 + N/A -175 + N/A -200 + N/A N/A N/A -258  
Missouri Tigers 155 Missouri
+10.5 -110 +0.5 -130 + N/A +0.5 -110 + N/A +1.5 -130 + +0.5 -135 + N/A N/A +6.5 -105  
Oklahoma Sooners 156 Oklahoma
-10.5 -110 -0.5 even + N/A -0.5 -120 + N/A -1.5 -102 + -0.5 +105 + N/A N/A -6.5 -115  
Missouri Tigers 155 Missouri
o42.5 -110 o10 -120 + N/A o10.5 -115 + N/A o10.5 +112 + o9.5 -135 + N/A N/A o42.5 -112  
Oklahoma Sooners 156 Oklahoma
u42.5 -110 u10 -110 + N/A u10.5 -115 + N/A u10.5 -140 + u9.5 +105 + N/A N/A u42.5 -108  
Missouri Tigers 155 Missouri
+275 +140 + N/A +124 + N/A +134 + N/A N/A N/A +210  
Oklahoma Sooners 156 Oklahoma
-345 -170 + N/A -160 + N/A -172 + N/A N/A N/A -258  

The Missouri Tigers will take on the Oklahoma Sooners in this week's NCAAF action. Kickoff is set for 12:00 p.m. EST at Gaylord Family Oklahoma Memorial Stadium in Norman, Okla. The game will be broadcast live on ABC. Here's everything you need to know about Missouri vs. Oklahoma odds, the latest NCAAF spreads, NCAAF over/unders and more.

The Oklahoma Sooners opened as a -7.5 point favorite over Missouri. The total is set at over/under 42.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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Oklahoma vs. Missouri Best Bet

In a battle of former Big 12 foes, Missouri will travel to Norman to take on Oklahoma, coming off its best win of the season.

This is a letdown for a Sooners' squad that was lucky to escape Tuscaloosa with a win. Oklahoma is the better team here but seven points is a lot to lay with a questionable offense at best.

On the other end, Missouri is fighting for its CFP lives. The Tigers have come up short in each of their matchups against ranked opponents, but this is their last chance to make an impression of the College Football Playoff committee. With desperation on their side, seven points are just too many. In a game with such a low total (42.5), we can expect Missouri to keep it close.

Make sure you bet this one at BetMGM Sportsbook to get the key number.

Oklahoma vs. Missouri Best Bet: Missouri +7 (-110)

(Pick from Derek Mountain)

Looking for more best bets? Check out our free college football picks and our premium subscription for the best picks!

What Time is the Oklahoma vs. Missouri Game?

The Missouri Tigers will take on the Oklahoma Sooners at 12:00 PM ET.

Where is the Missouri vs. Oklahoma Game Being Played?

This game is going to be played at Gaylord Family Oklahoma Memorial Stadium in Norman, OK.

How Can I Watch Missouri vs. Oklahoma?

You can watch Missouri vs. Oklahoma on ABC.

Can Missouri Beat Oklahoma?

Yes, absolutely this is a huge letdown spot for the Sooners coming off an upset over the Alabama Crimson Tide.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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