2022 LSU Tigers Betting Odds, Picks & Predictions


After a national championship season in 2019-20, the LSU Tigers have not adjusted well during the COVID years the past two seasons. After mass losses to the NFL, as well as a lack of practice time, the Tigers played to a 5-5 season during the strange 2020-21 campaign. Things weren't much better in the 2021-22 season, with the Tigers bottoming out at 6-7 with a loss in the Texas Bowl. It was Ed Orgeron's final season at the helm after leading the team to a national title.

The Tigers brought in head coach Brian Kelly and his oh-so-authentic "southern" accent to Baton Rouge to whip the Bayou Bengals into shape. By all indications, there is tremendous excitement about Kelly's arrival, as the Tigers had a bunch of incoming transfers.

The most notable incoming transfer might be QB Jayden Daniels, who showed some glimpses of brilliance during his time at Arizona State. He'll have a full quarterback room to contend with, though, as incumbent Myles Brennan, freshman Garrett Nussmeier and Walker Howard also dot the roster.

Updated on 04/13/2024
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When the Tigers aren't passing the pill, it will be RB John Emery Jr. carrying the mail out of the backfield. He was academically ineligible last season, but he could be a huge upgrade for this offense in 2022.

LSU had huge losses on the defensive side of the football, including all-everything CB Derek Stingley Jr., who was a high first-round NFL pick. The team actually lost a couple of players to the transfer portal, too, while gaining some talent via the same avenue. Greg Brooks Jr., incoming from Arkansas, might be the best add.

Kelly and the Tigers should get off to a very quick start, as the first four games all appear winnable. It's possible, but not likely, but possible...that the Tigers could be 8-0 heading into the Alabama game on Nov. 5 if things break right. I think the Tigers are tripped up somewhere along the line before that showdown, but LSU could be much, much better this season.

Over 6.5 Wins (-130) is a tremendous play, and perhaps the best team total in the SEC. The first eight games are all winnable, and the schedule has the potential to net the Tigers nine wins. You'll just need seven.

Best Bet: LSU Over 6.5 Wins (-130)


  • Sun., Sept. 4 - vs. FSU*
  • Sat., Sept. 10 - vs. Southern
  • Sat., Sept. 17 - vs. Mississippi State
  • Sat., Sept. 24 - vs. New Mexico
  • Sat., Oct. 1 - at Auburn
  • Sat., Oct. 8 - vs. Tennessee
  • Sat., Oct. 15 - at Florida
  • Sat., Oct. 22 - vs. Ole Miss
  • Sat., Nov. 5 - vs. Alabama
  • Sat., Nov. 12 - at Arkansas
  • Sat., Nov. 19 - vs. UAB
  • Sat., Nov. 26 - at Texas A&M


  • Over 6.5 (-130)
  • Under 6.5 (+100)



Let's pump the brakes a bit here. While I think Kelly makes an instant splash with a non-conference neutral-site win over Florida State and potentially seven or eight wins before the Alabama game, the Tigers aren't in the same class as the contenders of Alabama, Georgia or even Kentucky and Texas A&M just yet. However, LSU is on the right track, and it might be only a matter of time and another year or two of recruiting and transfer classes before LSU closes the gap on the top contenders.



LSU is just three seasons removed from a national championship, but it might be another two or three seasons away from legitimately contending for another glass football egg. As much as Kelly won at Notre Dame, winning more games than any other coach, and as much as he won at Central Michigan and Cincinnati, he also has zero CFP victories. So he has plenty of work to do before you can believe in LSU as a national title contender.

Jayden Daniels looks to win the QB job and turn things around at LSU. (Getty Images)


Jayden Daniels (QB) +7000

Kayshon Boutte (WR) +15000

Daniels was considered a legitimate Heisman Trophy sleeper heading into the 2021-22 campaign at Arizona State. However, that chatter was cooled off quickly at BYU in a mid-September loss, and then a pair of setbacks in October which had him out of the picture by Halloween. He managed to complete 66.4% of his pass attempts for 2,222 yards, but he managed just 10 touchdowns with nine interceptions, while running for 670 yards and six touchdowns with a 5.6 yards per gain average. He'll need exponential improvement, and that's just to secure the starting job in Baton Rouge.

There are too many questions surrounding Daniels and the LSU pass game, and WR Kayshon Boutte will not legitimately get a shot at a Heisman if his quarterback is either too inconsistent, or making big plays with his arm and feet.


  • SU: 6-7
  • ATS: 5-7-1
  • O/U: 6-7
  • ATS-Home: 3-3-1
  • ATS-Road: 2-4
  • ATS-Favorite: 2-4
  • ATS-Underdog: 3-3-1