NFL Hall of Fame Game Odds: Lines, Spreads, Betting Trends For Panthers vs. Cardinals

Patrick Everson Sports Betting Expert

1 minute read

2026 NFL Hall of Fame Game Odds

NFL Hall of Fame Game odds represent the return of America's favorite betting pastime. The public masses love nothing more than wagering on the NFL.

The first dose comes Thursday night in Canton, Ohio, as NFL preseason odds open with the Carolina Panthers vs. Arizona Cardinals.

Here’s everything you need to know about Hall of Fame Game NFL odds: opening lines, spreads and betting trends, as multiple sportsbooks provide insights on NFL preseason odds and action. Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

(Feature Image: Mark J. Rebilas/Imagn Images)

2026 NFL Preseason Odds

Carolina Panthers vs. Arizona Cardinals Odds

CAR @ ARI Odds

• Full Game
• 1H
• 1Q

• Spread
• Total
• Moneyline

Time	Open	BetMGM	DraftKings	Caesars	FanDuel	HardRock	RiversCasino	Consensus
	Open	›	›	›	›	›	›
101 Panthers	-1.5 -105	-1.5 -110	-1.5 even	-1.5 -105	-1.5 -104	--1.5 -110	-1.5 -108	-1.5 even
102 Cardinals	+1.5 -115	+1.5 -110	+1.5 -120	+1.5 -115	+1.5 -118	+-1.5 even	+1.5 -113	+1.5 -120
Matchup
	Open	›	›	›	›	›	›
101 Panthers	o35.5 -115	o35.5 -110	o36.5 -110	o35.5 -110	o35.5 -105	o35.5 -115	o35.5 -112	o36.5 -110
102 Cardinals	u35.5 -105	u35.5 -110	u36.5 -110	u35.5 -110	u35.5 -115	u35.5 -110	u35.5 -109	u36.5 -110
Matchup
	Open	›	›	›	›	›	›
101 Panthers	-120	-125	-118	-115	-112	-130	-121	-118
102 Cardinals	even	+105	-102	-105	-104	even	even	-102
Matchup

Time	Open	BetMGM	DraftKings	Caesars	FanDuel	HardRock	RiversCasino	Consensus
	Open	›	›	›	›	›	›
101 Panthers	-1.5 -105	N/A	-0.5 -105	-0.5 -105	-1.5 +118	N/A	N/A	-1.5 even
102 Cardinals	+1.5 -115	N/A	+0.5 -115	+0.5 -115	+1.5 -158	N/A	N/A	+1.5 -120
Matchup
	Open	›	›	›	›	›	›
101 Panthers	o35.5 -115	N/A	o19.5 even	o19.5 even	o17.5 -120	N/A	N/A	o36.5 -110
102 Cardinals	u35.5 -105	N/A	u19.5 -120	u19.5 -120	u17.5 -110	N/A	N/A	u36.5 -110
Matchup
	Open	›	›	›	›	›	›
101 Panthers	-120	N/A	-125	-121	-118	N/A	N/A	-118
102 Cardinals	even	N/A	+105	even	-112	N/A	N/A	-102
Matchup

Time	Open	BetMGM	DraftKings	Caesars	FanDuel	HardRock	RiversCasino	Consensus
	Open	›	›	›	›	›	›
101 Panthers	-1.5 -105	N/A	N/A	N/A	N/A	N/A	N/A	-1.5 even
102 Cardinals	+1.5 -115	N/A	N/A	N/A	N/A	N/A	N/A	+1.5 -120
Matchup
	Open	›	›	›	›	›	›
101 Panthers	o35.5 -115	N/A	N/A	N/A	N/A	N/A	N/A	o36.5 -110
102 Cardinals	u35.5 -105	N/A	N/A	N/A	N/A	N/A	N/A	u36.5 -110
Matchup
	Open	›	›	›	›	›	›
101 Panthers	-120	N/A	-122	N/A	-114	N/A	N/A	-118
102 Cardinals	even	N/A	+102	N/A	-114	N/A	N/A	-102
Matchup

• Opening point spread: Panthers -1.5
• Opening moneyline: Panthers -122/Cardinals +102
• Opening total: Over/Under 36.5 points scored
• Time: 8 p.m. ET Thursday (NBC)

OPENING ODDS UPDATE: Carolina opened as a 1.5-point favorite vs. Arizona in DraftKings Sportsbook's NFL Hall of Fame Game odds, for the traditional preseason kickoff in Canton, Ohio. As of 4 p.m. ET Monday, there's been no movement on this matchup.

The Panthers are coming off an 8-9 regular season (10-7 ATS), but somehow that was enough to win the dismal NFC South. Surprisingly, Carolina then gave the L.A. Rams a helluva fight before losing 34-31 as a 10.5-point Wild Card underdog at home.

Arizona was far worse last year, at 3-14 SU/6-11 ATS. Quarterback Kyler Murray played in just five games before getting shelved by a foot injury. The Cards proceeded to release Murray, who is now with the Minnesota Vikings.

For Thursday night, it's likely that few if any starters will see playing time for either team. QB Bryce Young is definitely sitting for the Panthers, who will start Kenny Pickett. The Cardinals haven't announced their starting QB yet, but the depth chart reads:

• Jacoby Brissett
• Gardner Minshew
• Carson Beck
• Kedon Slovis

Brissett started 12 games for Arizona last season, taking over for Murray. Beck is a rookie third-round pick who guided Miami to the 2025-26 national championship game, where the Hurricanes lost to Indiana 27-21. He was also a backup on two national title teams at Georgia.

Check back throughout this week for updates on Panthers vs. Cardinals odds and action.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson