NFL Odds Week 16: Ravens vs 49ers Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

3 minute read

Week 16 of the NFL season concludes with a heavyweight non-conference showdown on Christmas Night between the Baltimore Ravens and San Francisco 49ers. The betting odds see Baltimore as a 5.5-point underdog despite owning an impressive record of 11-3 on the season. Coverage begins from Levi's Stadium in Santa Clara on Monday, December 25 at 8:15 p.m. ET on ABC.

Here's everything you need to know about the NFL odds for Week 16: Ravens vs. 49ers lines, spreads, betting trends and more.

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Baltimore Ravens vs San Francisco 49ers Odds

• Opening point spread: 49ers -5
• Opening moneyline: 49ers -240/Ravens +190
• Opening total: Over/Under 47.5 points scored
• Time: 8:15 p.m. ET Monday (ABC)

UPDATE 8 P.M. ET MONDAY: Just before kickoff, San Francisco is up to a 6.5-point favorite at BetMGM. The Niners opened -5, got to 5.5 a couple times early last week and went to -6 Friday. This morning brought a brief recession to -5.5 (-125), but the number then moved to 49ers -6.5 this afternoon.

All that noted, the Ravens are actually getting 58% of spread bets/53% of spread money. Further, on the moneyline, tickets and money are in the 5/1 range on Baltimore.

"The 49ers to cover would probably be best," BetMGM Nevada's Scott Shelton said.

The total climbed from 45.5 to 47 by Wednesday, then backed up to 46 Sunday and this morning. But it's now up to 47.5, with tickets 2/1 and money 3/1 on the Over.

UPDATE 7 P.M. ET WEDNESDAY: San Fran moved from -5 to -5.5 in TwinSpires' NFL odds Week 16 market. The Niners are drawing 54% of early spread bets/63% of early spread money.

"Volume is already through the roof on this game. Sharp play on 49ers -5," Lucas said.

The total crept from 46.5 to 47, with 62% of bets/58% of cash on the Over.

UPDATE 10 P.M. ET SUNDAY: The Christmas Day tripleheader ends with one of the best matchups of the year. It's a showdown of the top two teams on most sportsbooks' Super Bowl odds boards.

San Francisco (11-3 SU/8-6 ATS) is on a six-game win streak (4-2 ATS). In Week 15, the Niners topped Arizona 45-29, cashing as 12.5-point faves.

Baltimore (11-3 SU/9-5 ATS) has won four in a row and eight of its last nine (6-3 ATS). In the Sunday nighter at Jacksonville, the Ravens notched a 23-7 victory giving 4 points.

Before Ravens-Jags kicked off, the Ravens-Niners total was already down a point to 46.5. Once Ravens-Jags started, Ravens-Niners came off the board at The SuperBook. The Baltimore-San Fran game will go back up Monday morning.

"This game will be terrible for the ratings of 'It's a Wonderful Life' or 'Miracle on 34^th Street' or whatever the counterprogramming will be. Because this will be a high-handle, high-viewership game on Christmas night," Michaelson said. "The line has moved down [from the -6/-5.5 lookahead] due to uncertainty with San Francisco's defensive injuries. We will almost certainly need Baltimore, as the Chiefs/Eagles/49ers moneyline parlay feels like an easy way to double your Christmas money.

"On Thanksgiving, we got an upset. We'll be looking for Lamar Jackson to play the role of the Grinch."

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 16 Report containing spreads, lines, and trends for every NFL matchup.

Ravens vs 49ers Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

Check back soon for picks!

Pick: TBD

For more NFL picks, check out Action Network's NFL Week 16: How to Bet Every Game & Every Team.

The One Stat to Know About Ravens vs 49ers

Action Network NFL researcher Evan Abrams offers his top betting stat:

Check back soon for betting stats!

For more NFL betting stats, check out Action Network's NFL Week 16 Betting Trends, Stats, Notes.

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Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson