Last Updated Oct 29, 2021, 11:00 PM

Tennessee Titans vs. Indianapolis Colts Predictions, Odds, Picks

Oct. 31, 2021
Joe Williams
VI Betting Expert

The Tennessee Titans (5-2) and Indianapolis Colts (3-4) meet for the second time this season, this time at Lucas Oil Stadium in Indianapolis for a Week 8 AFC South Divisional matchup. Kick off is scheduled for 1:00 p.m. ET and the game can be viewed on CBS.

Score Prediction

Titans 27, Colts 20

Best Bets

Titans ML


Tennessee Titans vs. Indianapolis Colts Predictions

<p.The Titans have racked up victories in a pair of marquee AFC battles in each of the past two weekends. In Week 6 on Monday night, the Titans upended the Buffalo Bills by a 34-31 count as six-point underdogs, and then they absolutely emasculated the Kansas City Chiefs by a 27-3 count last Sunday as four-point underdogs. While that was surprising, the UNDER result was also a bit of a shock, snapping a 3-0 OVER run.

Tennessee is 5-1 SU/ATS across the past six games, too, and the winning ways include a 25-16 victory over Indianapolis at Nissan Stadium as the Titans covered a 4.5-point number.

In the first meeting, Tennessee had a balanced attack with 180 rushing yards and 188 receiving yards. The Titans bottled up RB Jonathan Taylor a little bit, limiting him to 64 rushing yards, while also keeping QB Carson Wentz under 200 yards with no touchdown passes. Meanwhile, RB Derrick Henry steamed his way to 113 rushing yards, his first of five straight games over 100 yards before failing to hit the century mark last week. QB Ryan Tannehill was also under 200 yards passing, but he had three TD tosses.

Tennessee Titans vs. Indianapolis Colts Betting Odds

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Tennessee Titans vs. Indianapolis Colts Betting Resources

  • Matchup: AFC South
  • Date: Sunday, October 31, 2021
  • Venue: Lucas Oil Stadium
  • Location: Indianapolis, Indiana
  • TV-Time: CBS - 1:00 p.m. ET

Tennessee Titans Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 5-2
  • ATS: 5-2
  • O/U: 4-3
  • ATS - Home: 3-1
  • ATS - Away: 2-1

The Titans have covered three in a row, and Henry is looking like an MVP candidate. He tossed a touchdown pass last week to TE MyCole Pruitt to open the scoring against the Chiefs. The Titans did their part, going for 24 or more points for the sixth straight game, but they hit the UNDER for the first time in four outings with the defense stuffing QB Patrick Mahomes. In fact, it was the first team to keep Kansas City out of the end zone with Mahomes as a starter.

Tennessee is 5-1 ATS in the past six games overall, and 5-2 ATS in the past seven games as an underdog. The Titans are also 4-1 ATS in the past five inside the AFC South. While that’s all well and good, the Colts have been kryptonite for the Titans. Tennessee is just 6-14 ATS in the past 20 meetings, and 3-7 ATS in the past 10 trips to Indy.

Indianapolis Colts Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 3-4
  • ATS: 5-2
  • O/U: 4-3
  • ATS - Home: 2-1
  • ATS - Away: 3-1

The Colts gained a lot of confidence with a 30-18 win at San Francisco in a driving rainstorm, coming on the heels of a 31-3 rout of the Houston Texans last time at home. Indy has covered four straight games, and they easily could have stopped the Baltimore Ravens in Week 5 on SNF, but they blew a 25-16 lead in the fourth quarter and ended up losing in overtime.

Indianapolis has dominated this series in recent seasons, especially at home, but Tennessee rolled up a nine-point win and cover in the first meeting, and Henry has been a handful. The Colts, like everyone else, had difficulty stopping Henry in late September. Indy is just so-so against the run, yielding 111.0 rushing yards per contest. Henry will be the difference in this battle.

Inside the Stats - Tennessee Titans

  • Record: 5-2
  • Division Standing: 1st - AFC South
  • Points Scored: 193
  • Points Allowed: 164
  • PS/G: 27.6 (6th)
  • PA/G: 23.4 (16th)

Inside the Stats - Indianapolis Colts

  • Record: 3-4
  • Division Standing: 2nd - AFC South
  • Points Scored: 169
  • Points Allowed: 149
  • PS/G: 24.1 (15th)
  • PA/G: 21.3 (11th)

Key Players to Watch

  • TEN: Derrick Henry - RB (191 carries, 869 yards, 10 TD)
  • TEN: Ryan Tannehill - QB (149/229, 1,737 yards, 7 TD, 5 INT)
  • IND: Carson Wentz - QB (141/219, 1,695 yards, 11 TD, INT)
  • IND: Jonathan Taylor - RB (105 carries, 579 yards, 5 TD)

Tennessee Titans vs. Indianapolis Colts Betting Conclusion

An interesting thing about Henry is that he averages 2.8 yards per rush in the first quarter with just 131 yards and no touchdowns. In the second quarter he averages 5.3 yards per attempt with 211 yards and two touchdowns.

In the third quarter he averages 4.7 yards per attempt with 225 yards and three touchdowns, while going for 270 rushing yards on 5.6 yards per run and five scores. Yes, he gets stronger as the game goes on.

Indianapolis might seem like they’re corralling Henry early. Bettors who foolishly back the Colts might feel good about themselves in the first half even. But the Titans have rolled up impressive numbers in the second half, and that will be the blueprint in this rematch, too. Look for Indy to run away, literally, in the final 30 minutes.

Tennessee Titans vs. Indianapolis Colts Betting Trends

  • Tennessee has won eight of its last nine divisional games.
  • Tennessee has gone OVER the point total in nine of its last 10 games.
  • Tennessee has covered the spread in five of its last six games.
  • The point total has gone OVER in three of the last four meetings.
  • The favorite has covered the spread in three of the last four meetings.

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