Week 2: Lafayette vs Duke Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline

College football odds for Week 2 are on the board and receiving plenty of attention as we tackle all the major storylines of the weekend. The Lafayette Leopards and Duke Blue Devils meet at Wallace Wade Stadium in Durham on Saturday, September 9 at 6:00 p.m. ET on ESPN+.

Here's everything you need to know about the college football odds for the Week 2 game between Lafayette and Duke: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Lafayette vs No. 21 Duke Odds

  • Opening point spread: TBA
  • Opening moneyline: Duke TBA/Lafayette TBA
  • Opening total: Over/Under TBA points scored
  • Time: 6 p.m. ET Saturday (ESPN+/ACCNX)

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 2 Report containing spreads, lines, and trends for every Top 25 matchup.