College Football Odds Week 5: Missouri vs Vanderbilt Lines, Spreads, Betting Trends
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There will be plenty of black and gold in the stands in Nashville as Missouri travels to face Vanderbilt. The Tigers put their 4-0 record on the line as coverage begins from FirstBank Stadium on Saturday, September 30 at 4:00 p.m. ET on SEC Network.
Here's everything you need to know about the college football odds for Week 5 Missouri vs. Vanderbilt: the opening lines, spreads, betting trends and more. Check back regularly for updates.
No. 22 Missouri vs Vanderbilt Odds

- Opening point spread: Missouri -13
- Opening moneyline: Missouri -550/Vanderbilt +400
- Opening total: Over/Under 56.5 points scored
- Time: 4 p.m. ET Saturday (SEC Network)
UPDATE 2 P.M. ET FRIDAY: BetMGM jumped from Tigers -11.5 to -13.5 by Monday morning, and the line hasn't moved since. Early ticket count is 2.5/1 and early money 4/1 on favored Mizzou.
The total dipped from 56.5 to 54.5 by Wednesday. The Under is getting 56% of tickets/83% of dollars at BetMGM.
UPDATE 3 P.M. ET MONDAY: Mizzou (4-0 SU and ATS) got through nonconference play unscathed and has a relatively easy start to its SEC schedule. In Week 4, the Tigers topped Memphis 34-27 giving 6.5 points, in a quasi-neutral-site game in St. Louis.
Vanderbilt is on a three-game SU skid and is dead last in the nation with an 0-5 ATS mark. The Commodores (2-3 SU) were 13-point home pups to Kentucky and lost 45-28 in Week 4.
This number bounced around early in Caesars Sports' college football odds Week 5 market. Missouri opened -13 Sunday, backed up to -12 within a few hours, then climbed to -14 by this morning.
Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 5 Report containing spreads, lines, and trends for every Top 25 matchup.
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