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Indiana vs. Iowa: Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
Indiana vs. Iowa: Prediction, Odds, Best Bet

Image Credit: Rich Janzaruk via Imagn Images

IU @ IOWA Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
Indiana Hoosiers 133 Indiana
-3 -115 -4.5 -110 -4.5 -105 -3.5 -125 -4.5 -110 -5.5 -110 -4.5 -110 -4.5 -105 -4.5 -109 -9.5 -115  
Iowa Hawkeyes 134 Iowa
+3 -105 +4.5 -110 +4.5 -115 +3.5 -105 +4.5 -110 +5.5 -110 +4.5 -110 +4.5 -115 +4.5 -115 +9.5 -115  
Final
Indiana Hoosiers 133 Indiana
o50.5 -110 o23.5 -115 N/A o23.5 -112 o23.5 -115 o23.5 -118 o23.5 -120 o22.5 -135 o23.5 -112 o47.5 -115  
Iowa Hawkeyes 134 Iowa
u50.5 -110 u23.5 -105 N/A u23.5 -120 u23.5 -105 u23.5 -104 u23.5 -105 u22.5 +110 u23.5 -117 u47.5 -115  
Final
Indiana Hoosiers 133 Indiana
-265 -240 N/A -234 -240 -250 N/A N/A -265 -360  
Iowa Hawkeyes 134 Iowa
+215 +205 N/A +176 +205 +198 N/A N/A +195 +260  
Final
Indiana Hoosiers 133 Indiana
-3 -115 -3 even -2.5 -120 -0.5 -110 -3 +110 -2.5 -114 -2.5 -120 -1.5 -120 -2.5 -118 -9.5 -115  
Iowa Hawkeyes 134 Iowa
+3 -105 +3 -130 +2.5 -110 +0.5 -120 +3 -140 +2.5 -110 +2.5 -105 +1.5 -110 +2.5 -110 +9.5 -115  
Final
Indiana Hoosiers 133 Indiana
o50.5 -110 o10.5 even N/A o9.5 -125 o10 even o9.5 -135 o9.5 -125 o10.5 +115 o9.5 -148 o47.5 -115  
Iowa Hawkeyes 134 Iowa
u50.5 -110 u10.5 -130 N/A u9.5 -105 u10 -130 u9.5 +108 u9.5 +105 u10.5 -155 u9.5 +114 u47.5 -115  
Final
Indiana Hoosiers 133 Indiana
-265 -180 N/A -162 -180 -215 N/A N/A -215 -360  
Iowa Hawkeyes 134 Iowa
+215 +145 N/A +126 +150 +164 N/A N/A +160 +260  
Final
Indiana Hoosiers 133 Indiana
-3 -115 N/A N/A -5.5 -120 -3.5 -120 N/A N/A N/A N/A -9.5 -115  
Iowa Hawkeyes 134 Iowa
+3 -105 N/A N/A +5.5 -110 +3.5 even N/A N/A N/A N/A +9.5 -115  
Final
Indiana Hoosiers 133 Indiana
o50.5 -110 N/A N/A o23.5 -115 o22.5 -110 N/A o23.5 -105 N/A N/A o47.5 -115  
Iowa Hawkeyes 134 Iowa
u50.5 -110 N/A N/A u23.5 -115 u22.5 -110 N/A u23.5 -120 N/A N/A u47.5 -115  
Final
Indiana Hoosiers 133 Indiana
-265 N/A N/A -300 N/A N/A N/A N/A N/A -360  
Iowa Hawkeyes 134 Iowa
+215 N/A N/A +220 N/A N/A N/A N/A N/A +260  
Final
Indiana Hoosiers 133 Indiana
-3 -115 N/A N/A -2.5 -130 N/A -3.5 -106 -2.5 -120 N/A N/A -9.5 -115  
Iowa Hawkeyes 134 Iowa
+3 -105 N/A N/A +2.5 even N/A +3.5 -125 +2.5 -105 N/A N/A +9.5 -115  
Final
Indiana Hoosiers 133 Indiana
o50.5 -110 o13.5 -115 N/A o13.5 -110 N/A o3.5 -113 o13.5 -120 N/A N/A o47.5 -115  
Iowa Hawkeyes 134 Iowa
u50.5 -110 u13.5 -115 N/A u13.5 -120 N/A u3.5 -118 u13.5 -105 N/A N/A u47.5 -115  
Final
Indiana Hoosiers 133 Indiana
-265 -230 N/A -220 N/A -225 N/A N/A N/A -360  
Iowa Hawkeyes 134 Iowa
+215 +180 N/A +165 N/A +172 N/A N/A N/A +260  
Final
Indiana Hoosiers 133 Indiana
-3 -115 N/A N/A -3.5 -105 N/A -2.5 -128 -2.5 -110 N/A N/A -9.5 -115  
Iowa Hawkeyes 134 Iowa
+3 -105 N/A N/A +3.5 -125 N/A +2.5 -104 +2.5 -115 N/A N/A +9.5 -115  
Final
Indiana Hoosiers 133 Indiana
o50.5 -110 o10 -115 N/A o9.5 -142 N/A o2.5 -164 o9.5 -130 N/A N/A o47.5 -115  
Iowa Hawkeyes 134 Iowa
u50.5 -110 u10 -115 N/A u9.5 +110 N/A u2.5 +125 u9.5 even N/A N/A u47.5 -115  
Final
Indiana Hoosiers 133 Indiana
-265 -200 N/A -285 N/A -240 N/A N/A N/A -360  
Iowa Hawkeyes 134 Iowa
+215 +160 N/A +210 N/A +182 N/A N/A N/A +260  
Final
Indiana Hoosiers 133 Indiana
-3 -115 -0.5 -115 N/A -1.5 -115 N/A -1.5 -114 -0.5 -105 N/A N/A -9.5 -115  
Iowa Hawkeyes 134 Iowa
+3 -105 +0.5 -115 N/A +1.5 -115 N/A +1.5 -118 +0.5 -120 N/A N/A +9.5 -115  
Final
Indiana Hoosiers 133 Indiana
o50.5 -110 o12 -115 N/A o13.5 -105 N/A o12.5 -110 o13.5 -105 N/A N/A o47.5 -115  
Iowa Hawkeyes 134 Iowa
u50.5 -110 u12 -115 N/A u13.5 -125 N/A u12.5 -114 u13.5 -120 N/A N/A u47.5 -115  
Final
Indiana Hoosiers 133 Indiana
-265 -170 N/A -198 N/A -200 N/A N/A N/A -360  
Iowa Hawkeyes 134 Iowa
+215 +140 N/A +150 N/A +150 N/A N/A N/A +260  

The Indiana Hoosiers will take on the Iowa Hawkeyes in this week's NCAAF action. Kickoff is set for 3:30 p.m. EDT at Kinnick Stadium in Iowa City, Iowa. The game will be broadcast live on Peacock. Here's everything you need to know about Indiana vs. Iowa odds, the latest NCAAF spreads, NCAAF over/unders and more.

The Indiana Hoosiers opened as a -7.5 point favorite over Iowa. The total is set at over/under 48.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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Indiana Hoosiers vs. Iowa Hawkeyes Best Bet

Indiana had one of the more epic beatdowns of the 2025 NCAAF regular season to start.

IU QB Fernando Mendoza was absolutely dealing and a front 7 that is one of the best in terms of creating havoc, was in the backfield all night.

Now, they head to Iowa City to take on a pesky Hawkeyes team that is coming off a solid road win in Piscataway, NJ last Friday night.

Unlike other Iowa teams in the past, this iteration of the Hawkeyes can put up some points. Although some of their opponents were lackluster, they've managed to put up 34+ points in three of their four games.

They also have one of the nation's best ground attacks, which can help neutralize Indiana's terrorizing front.

This will be a tough spot for IU to get up for - I like the Hawkeyes to keep it close at home.

Indiana vs. Iowa Best Bet: Iowa +7.5

(Pick from Derek Mountain)

Looking for more best bets? Check out our free college football picks and our premium subscription for the best picks!

What Time Indiana Hoosiers vs. Iowa Hawkeyes Game?

The Indiana Hoosiers will take on the Iowa Hawkeyes at 3:30 ET on Saturday, September 27th.

Where is the Indiana Hoosiers vs. Iowa Hawkeyes Game Being Played?

This game is going to be played at Kinnick Stadium in Iowa City, Iowa.

How Can I Watch Indiana vs. Iowa?

You can watch Indiana vs. Iowa on Peacock.

Can Iowa Beat Indiana?

Yes, in fact the Vegas oddsmakers certainly think so as this spread opened at 7.5 points and is down all the way to just 3.5 points.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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