Oregon vs South Carolina Prediction, Picks, Odds | NCAA Tournament First Round Bets

The First Round of NCAA Men's Basketball Tournament kicks off on Thursday, March 21 -- and the seventh matchup on the slate set to tip off is Oregon vs South Carolina, which is scheduled for 4:00 p.m. ET on TNT.

The Ducks are short 1-point underdogs on the spread in Thursday's contest; with the game total stationed near over/under 143 at most sportsbooks.

Here's everything you need to know about Oregon vs South Carolina — our expert prediction and betting picks for this First Round NCAA Tournament matchup.

Oregon vs South Carolina Odds

OREGON @ SC Odds

Oregon vs South Carolina Prediction

Oregon wasn't exactly a lock to get into the NCAA Tournament as an at-large team, but took care of business by beating Colorado in the Pac-12 title game to grab the automatic bid.

The Ducks face a much-improved South Carolina squad that went from 11-21 last season to 26-7 this season. The Gamecocks surprised Tennessee, Kentucky, and Florida in SEC play, while slowing the tempo down to a crawl in each game.

Oregon started Pac-12 play at 5-0 before a 7-8 finish over the final 15 games. The Ducks went 1-5 against the Top-3 teams in the conference (Arizona, Washington State, and Colorado), but posted an 11-3 mark against the rest of the league, who all owned Pac-12 records of .500 or worse.

South Carolina should be able to bounce back here after getting routed by Auburn at the SEC tournament as the Gamecocks were 5-1 ATS this season as a favorite of 5.5 points or less.

Pick: South Carolina -1 (-110)

Oregon vs South Carolina Game Time & TV Channel

Date: Thursday, March 21
Matchup: Pac-12 vs SEC
Venue: PPG Paints Arena
Location: Pittsburgh, PA
Time-TV: TNT, 4:00 p.m. ET

Oregon vs South Carolina Betting Stats

6) South Carolina Gamecocks
(SEC, At-Large)

  • Futures: +12000
  • Region: +2800
  • SU: 26-7
  • ATS: 23-10
  • O/U: 16-17
  • PPG: 72.3
  • OPPG: 66.4

11) Oregon Ducks
(Pac-12, Automatic)

  • Futures: +22000
  • Region: +6000
  • SU: 23-11
  • ATS: 16-18
  • O/U: 20-4
  • PPG: 75.8
  • OPPG: 72.6

March Madness Betting Resources

March Madness First Round Odds

The NCAA Men's Tournament First Round will take place on Thursday March 21, 2024 and Friday March 22, 2024.

Check out the Teams, Odds, Betting Stats and much more on each of the four regions below: