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South Dakota State vs Iowa State Prediction, Picks, Odds | NCAA Tournament First Round Bets

Kevin Rogers
Kevin Rogers Sports Betting Expert
2 minute read

The First Round of NCAA Men's Basketball Tournament kicks off on Thursday, March 21 -- and the 12th matchup on the slate set to tip off is South Dakota State vs Iowa State, which is scheduled for 7:35 p.m. ET on truTV.

The Cyclones have climbed to 16.5-point favorites on the spread for Thursday's contest after originally opening at -14.5; with the game total stationed around over/under 135 at most sportsbooks.

Here's everything you need to know about South Dakota State vs Iowa State -- our expert prediction and betting picks for this First Round NCAA Tournament matchup.

South Dakota State vs Iowa State Odds

SDKST @ IAST Odds

  • Full Game
  • 1H
  • Spread
  • Total
  • Moneyline
Final
South Dakota State Jackrabbits 747 South Dakota State
+14.5 -102 +8.5 -110 N/A +8.5 -115 +8.5 -115 +9 -115 +8.5 -115 +9.5 -117 +15.5 -114  
Iowa State Cyclones 748 Iowa State
-14.5 -120 -8.5 -110 N/A -8.5 -115 -8.5 -115 -9 -115 -8.5 -115 -9.5 -109 -15.5 -106  
Final
South Dakota State Jackrabbits 747 South Dakota State
o134.5 -110 o63.5 -105 o63.5 -106 N/A o63.5 -110 o63 -120 o63.5 -110 o64.5 -112 o135.5 -104  
Iowa State Cyclones 748 Iowa State
u134.5 -110 u63.5 -115 u63.5 -118 N/A u63.5 -120 u63 -110 u63.5 -120 u64.5 -114 u135.5 -118  
Final
South Dakota State Jackrabbits 747 South Dakota State
+1160 N/A N/A +500 +400 +420 N/A +600 +980  
Iowa State Cyclones 748 Iowa State
-2800 N/A N/A -900 -700 -660 N/A -910 -2000  
Final
South Dakota State Jackrabbits 747 South Dakota State
+14.5 -102 +7 -110 +7.5 -112 N/A N/A N/A N/A +7.5 -117 +15.5 -114  
Iowa State Cyclones 748 Iowa State
-14.5 -120 -7 -110 -7.5 -112 N/A N/A N/A N/A -7.5 -109 -15.5 -106  
Final
South Dakota State Jackrabbits 747 South Dakota State
o134.5 -110 o72 -110 o71.5 -112 N/A N/A N/A N/A N/A o135.5 -104  
Iowa State Cyclones 748 Iowa State
u134.5 -110 u72 -110 u71.5 -112 N/A N/A N/A N/A N/A u135.5 -118  
Final
South Dakota State Jackrabbits 747 South Dakota State
+1160 N/A N/A N/A N/A N/A N/A N/A +980  
Iowa State Cyclones 748 Iowa State
-2800 N/A N/A N/A N/A N/A N/A N/A -2000  

South Dakota State vs Iowa State Prediction

Iowa State turned plenty of heads in the Big 12 championship by routing top-seed Houston, 69-41 as 5.5-point underdogs.

The Cyclones are the 2nd seed in the East region, but don't get much of a home-court advantage in Omaha as they face Summit League champion South Dakota State.

Iowa State owned the best defense efficiency ranking in the country, while holding Kansas State, Baylor, and Houston to 62 points or fewer in the Big 12 tournament.

The Jackrabbits will fire away as they rank 50th in the country in 3-point shooting at 36.2%, as South Dakota State is listed in its highest underdog spot of the season.

The expectations are high for Iowa State off the Big 12 tournament title as this is only the second time the Cyclones are a favorite in the Big Dance since 2021.

Pick: South Dakota State +16.5 (-110)

South Dakota State vs Iowa State Game Time & TV Channel

Date: Thursday, March 21
Matchup: Summit vs Big 12
Venue: CHI Health Center Omaha
Location: Omaha, Nebraska
Time-TV: truTV, 7:35 p.m. ET

South Dakota State vs Iowa State Betting Stats

2) Iowa State Cyclones
(Big 12, Automatic)

  • Futures: +1900
  • Region: +550
  • SU: 27-7
  • ATS: 22-10-2
  • O/U: 16-18
  • PPG: 75.7
  • OPPG: 62.1

15) South Dakota State Jackrabbits
(Summit, Automatic)

  • Futures: +40000
  • Region: +15000
  • SU: 22-12
  • ATS: 17-14
  • O/U: 15-15-1
  • PPG: 77.3
  • OPPG: 71.9

March Madness Betting Resources

March Madness First Round Odds

The NCAA Men's Tournament First Round will take place on Thursday March 21, 2024 and Friday March 22, 2024.

Check out the Teams, Odds, Betting Stats and much more on each of the four regions below:

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Kevin Rogers

Kevin Rogers

Kevin has been handicapping professionally since 2007 at VegasInsider before shifting to ScoresAndOdds. He focuses on MLB, NFL, college football, NBA, college basketball, and NHL and mainly uses trends, systems, and situations as his top handicapping angles. More from Kevin Rogers
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