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Featured Last Updated Aug 19 2026, 8:21 PM

2026 College Football Odds Week 1: Lines, Spreads, Betting Trends on Biggest Games

Patrick Everson
Patrick Everson Sports Betting Expert
13 minute read
2026 College Football Odds Week 1: Lines, Spreads, Betting Trends on Biggest Games

The College Football Odds Week 1 market stretches across two weekends, beginning Aug. 29.

North Carolina vs. TCU kicks off the season from Ireland. The more notable matchups arrive later in College Football Week 1 Odds: Clemson vs. LSU, Wisconsin vs. Notre Dame and SMU vs. Florida State.

Here’s everything you need to know about 2026 college football odds Week 1: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on Week 1 college football odds and action.

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Updated on 8/20/26

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2026 College Football Odds for Week 1

North Carolina vs. TCU Odds

UNC @ TCU Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
North Carolina Tar Heels 305 North Carolina
+6.5 -114 N/A N/A N/A N/A +4.5 -108 + N/A N/A N/A +7.5 -102  
TCU Horned Frogs 306 TCU
-6.5 -109 N/A N/A N/A N/A -4.5 -108 + N/A N/A N/A -7.5 -118  
North Carolina Tar Heels 305 North Carolina
o49.5 -115 N/A N/A N/A N/A o23.5 -128 + N/A N/A N/A o47.5 -110  
TCU Horned Frogs 306 TCU
u49.5 -108 N/A N/A N/A N/A u23.5 +104 + N/A N/A N/A u47.5 -110  
North Carolina Tar Heels 305 North Carolina
+195 N/A N/A N/A N/A +205 + N/A N/A N/A +260  
TCU Horned Frogs 306 TCU
-249 N/A N/A N/A N/A -270 + N/A N/A N/A -325  
North Carolina Tar Heels 305 North Carolina
+6.5 -114 N/A N/A N/A N/A +2.5 -106 + N/A N/A N/A +7.5 -102  
TCU Horned Frogs 306 TCU
-6.5 -109 N/A N/A N/A N/A -2.5 -116 + N/A N/A N/A -7.5 -118  
North Carolina Tar Heels 305 North Carolina
o49.5 -115 N/A N/A N/A N/A o9.5 -142 + N/A N/A N/A o47.5 -110  
TCU Horned Frogs 306 TCU
u49.5 -108 N/A N/A N/A N/A u9.5 +118 + N/A N/A N/A u47.5 -110  
North Carolina Tar Heels 305 North Carolina
+195 N/A N/A N/A N/A +174 + N/A N/A N/A +260  
TCU Horned Frogs 306 TCU
-249 N/A N/A N/A N/A -205 + N/A N/A N/A -325  
North Carolina Tar Heels 305 North Carolina
+6.5 -114 N/A N/A N/A N/A +2.5 +106 + N/A N/A N/A +7.5 -102  
TCU Horned Frogs 306 TCU
-6.5 -109 N/A N/A N/A N/A -2.5 -128 + N/A N/A N/A -7.5 -118  
North Carolina Tar Heels 305 North Carolina
o49.5 -115 N/A N/A N/A N/A o13.5 -118 + N/A N/A N/A o47.5 -110  
TCU Horned Frogs 306 TCU
u49.5 -108 N/A N/A N/A N/A u13.5 -104 + N/A N/A N/A u47.5 -110  
North Carolina Tar Heels 305 North Carolina
+195 N/A N/A N/A N/A +176 + N/A N/A N/A +260  
TCU Horned Frogs 306 TCU
-249 N/A N/A N/A N/A -210 + N/A N/A N/A -325  
North Carolina Tar Heels 305 North Carolina
+6.5 -114 N/A N/A N/A N/A +1.5 -120 + N/A N/A N/A +7.5 -102  
TCU Horned Frogs 306 TCU
-6.5 -109 N/A N/A N/A N/A -1.5 -102 + N/A N/A N/A -7.5 -118  
North Carolina Tar Heels 305 North Carolina
o49.5 -115 N/A N/A N/A N/A o10.5 +116 + N/A N/A N/A o47.5 -110  
TCU Horned Frogs 306 TCU
u49.5 -108 N/A N/A N/A N/A u10.5 -140 + N/A N/A N/A u47.5 -110  
North Carolina Tar Heels 305 North Carolina
+195 N/A N/A N/A N/A +146 + N/A N/A N/A +260  
TCU Horned Frogs 306 TCU
-249 N/A N/A N/A N/A -188 + N/A N/A N/A -325  
North Carolina Tar Heels 305 North Carolina
+6.5 -114 N/A N/A N/A N/A +1.5 -120 + N/A N/A N/A +7.5 -102  
TCU Horned Frogs 306 TCU
-6.5 -109 N/A N/A N/A N/A -1.5 -102 + N/A N/A N/A -7.5 -118  
North Carolina Tar Heels 305 North Carolina
o49.5 -115 N/A N/A N/A N/A o13.5 +102 + N/A N/A N/A o47.5 -110  
TCU Horned Frogs 306 TCU
u49.5 -108 N/A N/A N/A N/A u13.5 -124 + N/A N/A N/A u47.5 -110  
North Carolina Tar Heels 305 North Carolina
+195 N/A N/A N/A N/A +140 + N/A N/A N/A +260  
TCU Horned Frogs 306 TCU
-249 N/A N/A N/A N/A -166 + N/A N/A N/A -325  
  • Opening point spread: TCU -6.5
  • Opening moneyline: TCU -250/North Carolina +200
  • Opening total: Over/Under 49.5 points scored
  • Time: Noon ET Saturday, Aug. 29 (ESPN)

OPENING ODDS UPDATE: If odds are any indication, then the start of Bill Belichick's second year at North Carolina could prove as bumpy as Year 1. The Tar Heels went 4-8 SU/5-7 ATS, ending the season on slides of 0-3 SU and 0-4 ATS.

Texas Christian was far better, at 9-4 SU/7-6 ATS. The Horned Frogs capped the season with 30-27 Alamo Bowl victory as 4.5-point underdogs vs. USC.

Last season began with Belichick's troops getting waxed by TCU 48-14 as 3.5-point home underdogs. So there's certainly a revenge factor for the Heels in this extremely neutral-site game, in Dublin, Ireland.

However, the Horned Frogs are already laying more than a touchdown. BetMGM opened TCU as 6.5-point chalk, and on Aug. 19, the line is out to TCU -7.5 (-115) in the college football odds Week 1 market.

Ten days pre-kickoff, action is surely very light. But it's all TCU on the spread, at 92% of early tickets/94% of early money.

BetMGM opened the total at 49.5 and got bet down to 47.5. That said, it's two-way play, with 60% of bets on the Under/63% of money on the Over.

Memphis vs. UNLV Odds

MEM @ UNLV Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Memphis Tigers 315 Memphis
+3 -115 N/A N/A N/A N/A +3.5 -100 + N/A N/A N/A +6 -110  
UNLV Rebels 316 UNLV
-3 -105 N/A N/A N/A N/A -3.5 -116 + N/A N/A N/A -6 -110  
Memphis Tigers 315 Memphis
o60.5 -112 N/A N/A N/A N/A o28.5 -104 + N/A N/A N/A o57.5 -108  
UNLV Rebels 316 UNLV
u60.5 -108 N/A N/A N/A N/A u28.5 -118 + N/A N/A N/A u57.5 -112  
Memphis Tigers 315 Memphis
+145 N/A N/A N/A N/A +164 + N/A N/A N/A +185  
UNLV Rebels 316 UNLV
-175 N/A N/A N/A N/A -205 + N/A N/A N/A -225  
Memphis Tigers 315 Memphis
+3 -115 N/A N/A N/A N/A +1.5 -120 + N/A N/A N/A +6 -110  
UNLV Rebels 316 UNLV
-3 -105 N/A N/A N/A N/A -1.5 -102 + N/A N/A N/A -6 -110  
Memphis Tigers 315 Memphis
o60.5 -112 N/A N/A N/A N/A o13.5 -112 + N/A N/A N/A o57.5 -108  
UNLV Rebels 316 UNLV
u60.5 -108 N/A N/A N/A N/A u13.5 -108 + N/A N/A N/A u57.5 -112  
Memphis Tigers 315 Memphis
+145 N/A N/A N/A N/A +148 + N/A N/A N/A +185  
UNLV Rebels 316 UNLV
-175 N/A N/A N/A N/A -174 + N/A N/A N/A -225  
Memphis Tigers 315 Memphis
+3 -115 N/A N/A N/A N/A +1.5 -110 + N/A N/A N/A +6 -110  
UNLV Rebels 316 UNLV
-3 -105 N/A N/A N/A N/A -1.5 -110 + N/A N/A N/A -6 -110  
Memphis Tigers 315 Memphis
o60.5 -112 N/A N/A N/A N/A o16.5 -110 + N/A N/A N/A o57.5 -108  
UNLV Rebels 316 UNLV
u60.5 -108 N/A N/A N/A N/A u16.5 -110 + N/A N/A N/A u57.5 -112  
Memphis Tigers 315 Memphis
+145 N/A N/A N/A N/A +140 + N/A N/A N/A +185  
UNLV Rebels 316 UNLV
-175 N/A N/A N/A N/A -166 + N/A N/A N/A -225  
Memphis Tigers 315 Memphis
+3 -115 N/A N/A N/A N/A +1.5 -124 + N/A N/A N/A +6 -110  
UNLV Rebels 316 UNLV
-3 -105 N/A N/A N/A N/A -1.5 +102 + N/A N/A N/A -6 -110  
Memphis Tigers 315 Memphis
o60.5 -112 N/A N/A N/A N/A o13.5 -106 + N/A N/A N/A o57.5 -108  
UNLV Rebels 316 UNLV
u60.5 -108 N/A N/A N/A N/A u13.5 -116 + N/A N/A N/A u57.5 -112  
Memphis Tigers 315 Memphis
+145 N/A N/A N/A N/A +140 + N/A N/A N/A +185  
UNLV Rebels 316 UNLV
-175 N/A N/A N/A N/A -180 + N/A N/A N/A -225  
Memphis Tigers 315 Memphis
+3 -115 N/A N/A N/A N/A +1.5 -132 + N/A N/A N/A +6 -110  
UNLV Rebels 316 UNLV
-3 -105 N/A N/A N/A N/A -1.5 +108 + N/A N/A N/A -6 -110  
Memphis Tigers 315 Memphis
o60.5 -112 N/A N/A N/A N/A o14.5 -102 + N/A N/A N/A o57.5 -108  
UNLV Rebels 316 UNLV
u60.5 -108 N/A N/A N/A N/A u14.5 -120 + N/A N/A N/A u57.5 -112  
Memphis Tigers 315 Memphis
+145 N/A N/A N/A N/A +124 + N/A N/A N/A +185  
UNLV Rebels 316 UNLV
-175 N/A N/A N/A N/A -146 + N/A N/A N/A -225  
  • Opening point spread: UNLV -3.5
  • Opening moneyline: UNLV -220/Memphis +180
  • Opening total: Over/Under 58.5 points scored
  • Time: 10 p.m. ET Saturday, Aug. 29 (FOX)

OPENING ODDS UPDATE: For decades, UNLV was a college football wasteland. But the Rebels are riding three straight seasons of nine or more wins, including a 10-4 SU campaign in 2025-26 (7-7 ATS).

In fact, UNLV was 10-2 in the regular season. But the Rebels lost to Boise State 38-21 catching 5.5 points in the Mountain West title game, then fell to Ohio 17-10 laying 6.5 points in the Frisco Bowl.

Memphis went 8-1 SU and ATS in its first nine games last year, spurring the prospect of a possible Group of 6 College Football Playoff berth. But the Tigers tumbled from there, losing their final three regular-season games.

Then in the Gasparilla Bowl, Memphis got blasted by North Carolina State 31-7 as a 3.5-point 'dog, finishing the season at 8-5 SU and ATS.

BetMGM opened UNLV -3.5 in college football Week 1 odds, and the Rebels are now nearly double that at -6.5 (-105). Early spread play has 62% of bets/64% of cash on UNLV.

The total is down to 56.5 (Over -115) from a 58.5 opener. Early action is light and disparate, with 68% of bets on the Over/87% of money on the Under.

Boise State vs. Oregon Odds

  • Opening point spread: Oregon -24.5
  • Opening moneyline: Oregon -3000/Boise State +1200
  • Opening total: Over/Under 53.5 points scored
  • Time: 3:30 p.m. ET Saturday, Sept. 5 (CBS)

OPENING ODDS UPDATE: Oregon is No. 2 in the AP preseason poll, again expected to contend for the national title. Last season, the Ducks went 13-2 SU/9-6 ATS, reaching the College Football Playoff semifinals.

However, in that round, Oregon was a 3.5-point pup and got pounded by eventual champion Indiana 56-22.

Boise State went 9-5 SU/8-6 ATS last year, winning the Mountain West title in the process. But the Broncos ended on a losing note, falling to Washington 38-10 as 9.5-point underdogs in the LA Bowl.

Then Boise moved into the remade Pac-12, which now includes just two original Pac-12 outfits: Oregon State and Washington State.

Check back for more on Boise State vs. Oregon State College Football Week 1 odds.

Clemson vs. LSU Odds

  • Opening point spread: LSU -10.5
  • Opening moneyline: LSU -400/Clemson +300
  • Opening total: Over/Under 51.5 points scored
  • Time: 7:30 p.m. ET Saturday, Sept. 5 (ABC)

OPENING ODDS UPDATE: There's a new sheriff in town at LSU, with Lane Kiffin jumping from Ole Miss. LSU fired coach Brian Kelly on Oct. 26, in the middle of a season-killing 1-4 SU slide.

The Tigers finished 7-6 SU/4-9 ATS, including a 38-35 loss catching 1.5 points vs. Houston in the Texas Bowl.

Clemson was similarly disappointing last year, going 7-6 SU/5-8 ATS. Dabo Swinney's outfit finished with a 22-10 loss as a 2.5-point favorite vs. Penn State in the Pinstripe Bowl.

In this battle of purple Tigers vs. orange Tigers, LSU opened as a double-digit home favorite. Check back later for more on this matchup in College Football Odds Week 1.

Wisconsin vs. Notre Dame Odds

  • Opening point spread: Notre Dame -20.5
  • Opening moneyline: Notre Dame -2000/Wisconsin +1000
  • Opening total: Over/Under 47.5 points scored
  • Time: 7:30 p.m. ET Sunday, Sept. 6 (NBC)

OPENING ODDS UPDATE: No. 4 Notre Dame was a bride left at the altar in last season's College Football Playoff. The Fighting Irish lost their first two games, then won 10 in a row, but got edged out by Miami for the final spot in the 12-team field.

Notre Dame then opted not to accept a bowl bid, finishing the season 10-2 SU/6-6 ATS.

Wisconsin is coming off a dismal 4-8 SU campaign (6-6 ATS). After winning their first two outings, the Badgers went on a six-game nosedive before going 2-2 SU/3-1 ATS in their final four games.

Wisconsin vs. Notre Dame is a quasi-neutral-site contest at Lambeau Field. Check back for more on College Football Week 1 Odds in this matchup.

Louisville vs. Ole Miss Odds

  • Opening point spread: Ole Miss -6.5
  • Opening moneyline: Ole Miss -278/Louisville +225
  • Opening total: Over/Under 55.5 points scored
  • Time: 7:30 p.m. ET Sunday, Sept. 6 (ABC)

OPENING ODDS UPDATE: Ole Miss made a semi-surprising run at the CFP championship last season, going 13-2 SU/9-6 ATS. Behind QB Trinidad Chambliss, the Rebels got all the way to the semis, then fell just short to Miami 31-27 as 3.5-point 'dogs.

Chambliss returns this season, but coach Lane Kiffin left for LSU even before Mississippi's CFP run. Pete Golding took over as coach for the Rebels, who are No. 9 in the AP presesaon poll.

No. 24 Louisville was in the CFP conversation after a 7-1 start last year. However, a late-season three-game slide ended that discussion. The Cardinals finished 9-4 SU, capped by a 27-22 win over Toledo in the Boca Raton Bowl.

But as was the case much of the season, the Cards (4-9 ATS) failed to cover as 12.5-point favorites.

Louisville vs. Ole Miss odds are slightly impacted by this being another Week 1 neutral-site game, taking place in Nashville. Check back later for more on this Top 25 matchup.

SMU vs. Florida State Odds

  • Opening point spread: SMU -2.5
  • Opening moneyline: SMU -142/Florida State +120
  • Opening total: Over/Under 53.5 points scored
  • Time: 7:30 p.m. ET Monday, Sept. 7 (ESPN)

OPENING ODDS UPDATE: Florida State is coming off two straight lackluster seasons, though last year's 5-7 SU record was a substantial upgrade from 2-10 SU in 2024-25. Still, the Seminoles lost three of their last four, including a 40-21 setback getting 1.5 points at Florida.

That gave the 'Noles a 5-7 ATS mark, as well.

Meanwhile, SMU went 9-4 SU/6-7 ATS last season. The Mustangs wrapped up the year with a 24-19 Holiday Bowl victory laying 2.5 points vs. Arizona.

Either Florida State or SMU will get out of the gate 1-0 in the ACC, with the Mustangs a short road favorite as of Aug. 19. Check back for more on College Football Odds Week 1 as this matchup draws closer.

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Patrick Everson

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson
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