College Football Odds Week 2: Southern Miss vs Florida State Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Florida State vs
Southern Miss
-29.5 (-114)
+29.5 (-106)
o54.5 (-110)
u54.5 (-110)

College football odds for Week 2 are on the board and receiving plenty of attention as we tackle all the major storylines of the weekend. The Southern Miss Golden Eagles and Florida State Seminoles meet at Doak Campbell Stadium in Tallahassee on Saturday, September 9 at 8:30 p.m. ET on the ACC Network.

Here's everything you need to know about the college football odds for the Week 2 game between Southern Miss and Florida State: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Southern Miss vs No. 4 Florida State Odds

  • Opening point spread: Florida State -27.5
  • Opening moneyline: Florida State TBA/Southern Miss TBA
  • Opening total: Over/Under 52.5 points scored
  • Time: 8:30 p.m. ET Saturday (ACC Network)

UPDATE 1:30 P.M. ET FRIDAY: BetMGM's college football odds Week 2 market opened Florida State -28.5 Sunday and by Tuesday was out to Seminoles -31. That's where the line remains this afternoon, with the 'Noles getting a modest majority 55% of tickets/58% of money on the spread.

The total combed from 51.5 to 53 by Tuesday and hasn't moved since. Practically all the tickets and money are on the Over at this point.

UPDATE 2 P.M. ET MONDAY: Florida State played in the biggest game of Week 1, a Sunday night neutral-site showdown in Orlando against LSU. The eighth-ranked Seminoles met the moment, hammering the No. 5 Tigers 45-24 as 1.5-point underdogs.

Southern Miss (1-0 SU and ATS) took care of FCS foe Alcorn State 40-14, covering as a 24.5-point home fave.

Hours before Florida State kicked off against LSU, Caesars Sports opened the Seminoles -27.5 vs. Southern Miss, then went to -28. This morning, the line went straight to 'Noles -29.5. There's no moneyline nor total listed yet.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 2 Report containing spreads, lines, and trends for every Top 25 matchup.