College Football Odds Week 3: Kansas State vs Missouri Lines, Spreads, Betting Trends
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College football odds for Week 3 are on the board and receiving plenty of attention as we tackle all the major storylines of the weekend. The Kansas State Wildcats and Missouri Tigers meet at Faurot Field in Columbia on Saturday, September 16 at 12:00 p.m. ET on SEC Network.
Here's everything you need to know about the college football odds for the Week 3 game between Kansas State vs Missouri: the opening lines, spreads, betting trends and more. Check back regularly for updates.
Kansas State vs. Missouri Odds

- Opening point spread: Kansas State -4.5
- Opening moneyline: Kansas State -220/Missouri +180
- Opening total: Over/Under 46 points scored
- Time: Noon ET Saturday (SEC Network)
UPDATE 2 P.M. ET THURSDAY: Kansas State hit PointsBet's college football odds Week 3 market as a 5.5-point favorite. The Wildcats are now down to -3.5 in this Big 12-SEC clash.
However, early ticket count is 7/1 and early money 9/1 on favored K-State.
The total rose from 46.5 to 48 and is now 47.5, with tickets 2.5/1 on the Over and money 7/1 on the Under.
UPDATE 1 P.M. ET MONDAY: Kansas State (2-0 SU and ATS) takes a step up in class for Week 3, after a couple of easy early opponents. In Week 2, the Wildcats beat Troy 42-13 giving 15.5 points at home.
Missouri (2-0 SU/0-2 ATS) was a favorite of three touchdowns or more in Weeks 1 and 2, and couldn't cover either big number. In Week 2, the Tigers were laying 21 points at home against Middle Tennessee and scratched out a 23-19 victory.
This line is already up a point in Caesars Sports' college football odds Week 3 market, with the Wildcats now -5.5.
Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 3 Report containing spreads, lines, and trends for every Top 25 matchup.
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